During Ramadan, HbA1c Changes in Type 2 Diabetes

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During Ramadan, HbA1c Changes in Type 2 Diabetes
During Ramadan, HbA1c Changes in Type 2 Diabetes

(HealthDay News) — For patients with type 2 diabetes, during Ramadan, the greatest change among metabolic parameters is seen for glycemia, according to a study published in the Journal of Diabetes Investigation.

Melanie Y.L. Siaw, from the National University of Singapore, and colleagues conducted a retrospective study using a national electronic database to examine trends in HbA1c, systolic blood pressure (BP), LDL cholesterol and triglycerides in patients with type 2 diabetes during Ramadan. 

A total of 5,172 eligible patients were categorized according to their HbA1c control before Ramadan: Group 1, HbA1c of 10% or greater; Group 2, HbA1c, 7.1% to 9.9%; Group 3, HbA1c of 7.0% or lower.

The researchers observed variation in the mean change of HbA1c, from −1.4% to +0.2%, with the greatest decrease seen in Group 1 (P<.001). 

In groups 2 and 3, there was a minimal reduction in systolic BP (2 mm Hg; P<.01). Changes in LDL and triglycerides were insignificant. 

In patients taking oral antidiabetic agents during Ramadan, there was a small (0.1%) reduction in mean HbA1c (P<.001).

"In conclusion, among the known metabolic parameters, the greatest change was observed in glycemia during Ramadan," the researchers wrote. "Patients with a mean baseline HbA1c value of 10% or more experienced the greatest HbA1c reduction."


  1. Siaw MYL et al. J Diabetes Investig. 2015;doi:10.1111/jdi.12374.
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