Type 2 Diabetes

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

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Researchers analyzed how improvements in metabolic syndrome may impact the risk of developing type 2 diabetes and cardiovascular disease in patients with prediabetes.

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

For patients with severe obesity and type 2 diabetes, bariatric surgery is associated with a lower risk for macrovascular outcomes compared with not undergoing surgery.

Bone-Derived Factors in the Treatment of Diabetes

Bone-Derived Factors in the Treatment of Diabetes

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A growing body of research highlights the important role of bone in glucose metabolism.

Periodic Fasting May Reduce Medication Use in T2D

Periodic Fasting May Reduce Medication Use in T2D

Medically supervised, therapeutic fasting regimens can help reverse type 2 diabetes (T2D) and minimize the need for pharmacological interventions.

Quick Take: Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial

Glucagon-like peptide-1 (GLP-1) potentiates the release of insulin from pancreatic beta cells in a glucose-dependent manner.

Cost a key consideration of WHO guidelines for diabetes treatment intensification

WHO guidelines recommend selecting sulfonylureas as the single best second-line agent for Type 2 Diabetes Mellitus (T2DM) patients.

High Levels of Prolactin in Women Inversely Linked to T2D Risk

High Levels of Prolactin in Women Inversely Linked to T2D Risk

Among U.S. women, a normally high circulating prolactin concentration is associated with a reduced risk for type 2 diabetes.

Fasting Glycemic Variability Indicates Increased Risk for Type 2 Diabetes

Fasting Glycemic Variability Indicates Increased Risk for Type 2 Diabetes

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Greater variation of fasting plasma glucose over time is associated with an increased risk of developing type 2 diabetes.

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

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Osteoarthritis was the most common form of arthritis in patients with diabetes but rheumatoid arthritis had the most pronounced association with diabetes.

Sitagliptin Provides Better Glycemic Control Than Dapagliflozin in T2D With Renal Impairment

Sitagliptin Provides Better Glycemic Control Than Dapagliflozin in T2D With Renal Impairment

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Study results indicated that sitagliptin showed greater glycemic efficacy than dapagliflozin treatment.

Cardiovascular Outcomes for Albiglutide Treatment in T2D

Cardiovascular Outcomes for Albiglutide Treatment in T2D

For patients with type 2 diabetes and existing cardiovascular disease, albiglutide results in fewer cardiovascular events.

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

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For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

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Risk for type 2 diabetes, ischemic heart disease, and peripheral vascular disease was elevated among patients with psoriatic arthritis compared with the general population.

Lixisenatide Reduces Kidney Damage in T2D With Coronary Syndrome

Lixisenatide Reduces Kidney Damage in T2D With Coronary Syndrome

For patients with type 2 diabetes and acute coronary syndrome, lixisenatide can slow or prevent damage to the kidneys.

Lorcaserin Reduces Risk for Incident Diabetes in Patients With Prediabetes

Lorcaserin Reduces Risk for Incident Diabetes in Patients With Prediabetes

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In this new analysis, researchers looked at the long-term effects of the drug on diabetes prevention and remission in these patients.

Updated ADA, EASD Consensus Guidelines for Managing Hyperglycemia in T2D

Updated ADA, EASD Consensus Guidelines for Managing Hyperglycemia in T2D

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Recommendations in the report highlight the importance of patient-centered decision making for glycemic management and improving diet and exercise for patients with T2D.

Obesity Reduces Number of Disease-Free Years Regardless of Lifestyle

Obesity Reduces Number of Disease-Free Years Regardless of Lifestyle

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Obesity is associated with loss of disease-free years irrespective of position in the social hierarchy and lifestyle.

FDA Issues Safety Communication Regarding Pen Needle Use

FDA Issues Safety Communication Regarding Pen Needle Use

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Standard pen needles have an outer cover and removable inner needle cover, while safety pen needles have an outer cover and a fixed inner needle shield that is not removed before an injection.

Basal Insulin Combination Therapies With Vildagliptin or Lixisenatide Equally Effective for T2D

Basal Insulin Combination Therapies With Vildagliptin or Lixisenatide Equally Effective for T2D

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Combination therapies of basal insulin with either vildagliptin or lixisenatide are similarly effective at producing glycemic control improvements.

Genetics May Identify Type 2 Diabetes Subtypes

Genetics May Identify Type 2 Diabetes Subtypes

Clusters of type 2 diabetes loci and traits have been identified.

Sleep Disturbances Affect Glycemic Control in Patients With Type 2 Diabetes

Sleep Disturbances Affect Glycemic Control in Patients With Type 2 Diabetes

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Findings from the study showed a graded association between shorter average sleep duration and higher HbA1c concentrations among participants with diabetes.

Replacing Red Meat With Poultry or Fish Lowers Type 2 Diabetes Risk

Replacing Red Meat With Poultry or Fish Lowers Type 2 Diabetes Risk

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Substituting processed red meat with poultry or fish and replacing total red meat with fish were associated with a lowered risk for type 2 diabetes.

Investigating the Link Between Atrial Fibrillation and Type 2 Diabetes

Investigating the Link Between Atrial Fibrillation and Type 2 Diabetes

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Compared with the general population, patients with type 2 diabetes are at a 35% to 60% greater risk for atrial fibrillation.

CPAP Therapy for Sleep Apnea Does Not Improve Diabetic Macular Edema in T2D

CPAP Therapy for Sleep Apnea Does Not Improve Diabetic Macular Edema in T2D

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Continuous positive airway pressure for obstructive sleep apnea in patients with type 2 diabetes offered no improvement in visual acuity compared with usual care alone.

Effect of Baseline Characteristics on Glycemic Control With Insulin Glargine in T2D

Effect of Baseline Characteristics on Glycemic Control With Insulin Glargine in T2D

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Investigators examined the effects of insulin glargine 300 U/mL vs insulin glargine 100 U/mL on glycated hemoglobin, hypoglycemia, and body weight change.

Time in Range According to CGM Associated With Diabetic Retinopathy

Time in Range According to CGM Associated With Diabetic Retinopathy

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Investigators assessed the time in range according to a continuous glucose monitor and the risk for diabetic retinopathy.

Muscle Cell Profiles Relate to Exercise Response Variation in Type 2 Diabetes

Muscle Cell Profiles Relate to Exercise Response Variation in Type 2 Diabetes

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Researchers aimed to determine whether variations in phosphocreatine recovery rates were marked by distinct epigenomic muscle profiles that could be seen prior to training.

Pharmacotherapy Personalization May Optimize Outcomes for Type 2 Diabetes

Pharmacotherapy Personalization May Optimize Outcomes for Type 2 Diabetes

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Investigators examined patient factors that affect the use of diabetes medication in patients with type 2 diabetes.

Lower Hypoglycemia Risk, Greater Weight Loss With SGLT2 Inhibitor, Sulfonylurea in T2D

Lower Hypoglycemia Risk, Greater Weight Loss With SGLT2 Inhibitor, Sulfonylurea in T2D

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SGLT-2i exhibited superior effects in terms of weight loss and did not increase the risk for hypoglycemia in dual therapy with sulfonylurea.

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