Inverse Relationship Between Sleep Duration and Risk of T2D in Children
Researchers identified strong inverse graded relationships between children's sleep duration, adiposity, and the presence of diabetes risk markers.
HealthDay News — There is an inverse correlation between sleep duration and risk markers of type 2 diabetes (T2D) in childhood, according to a study published online in Pediatrics.
Alicja R. Rudnicka, PhD, from the University of London, and colleagues conducted a cross-sectional study involving 4525 multiethnic UK children aged 9 to 10 years to examine the correlations between self-reported sleep duration and T2D risk markers.
The researchers found that children slept 10.5 hours per night on average. Strong inverse graded relationships were identified between sleep duration, adiposity, and diabetes risk markers. A 1-hour longer sleep duration correlated with 0.19 kg/m² lower BMI, 0.03 kg/m5 lower fat mass index, 2.9% lower homeostasis model assessment of insulin resistance, and 0.24% lower fasting glucose, in adjusted models; no correlations were seen for HbA1c or cardiovascular risk. After adjustment for adiposity markers, associations with insulin and glucose remained.
"The finding of an inverse association between sleep duration and T2D risk markers in childhood is novel," the authors write. "Intervention studies are needed to establish the causality of these associations, which could provide a simple strategy for early T2D prevention."
- Rudnicka AR, Nghtingale CM, Sonin AS, et al. Sleep duration and risk of type 2 diabetes [published online August 15, 2017]. Pediatrics. doi:10.1542/peds.2017-0338
- Glaser N, Styne D. Weighing the causal evidence that associates short sleep duration with obesity [published online August 15, 2017]. Pediatrics. doi:10.1542/peds.2017-2015