Type 2 Diabetes Archive

ADA's 2019 Standards of Medical Care in Diabetes Focus on Patient-Centered Care

ADA's 2019 Standards of Medical Care in Diabetes Focus on Patient-Centered Care

The ADA published its 2019 Standards of Medical Care in Diabetes, an evidence-based document intended to provide clinicians, patients, and other stakeholders in the diabetes treatment landscape with up-to-date recommendations.

SGLT2 Inhibitors and Urinary Tract Infections: What's the Link?

SGLT2 Inhibitors and Urinary Tract Infections: What's the Link?

For this study, the authors identified randomized controlled trials (RCTs) that compared SGLT2 inhibitors with placebo, no treatment, or another antidiabetic agent and reported on UTI outcome.

Metabolic Syndrome Highly Prevalent in Patients With Plaque Psoriasis

Metabolic Syndrome Highly Prevalent in Patients With Plaque Psoriasis

Metabolic syndrome and psoriatic arthritis were highly prevalent comorbidities in patients with plaque psoriasis.

T2D Linked to Decline in Verbal Memory, Fluency in Older Adults

T2D Linked to Decline in Verbal Memory, Fluency in Older Adults

Type 2 diabetes is associated with declines in verbal memory and fluency among older community-dwelling adults.

Low-Risk Patients With T2D May Be Self-Testing Blood Glucose Too Often

Low-Risk Patients With T2D May Be Self-Testing Blood Glucose Too Often

Patients with stable type 2 diabetes may be unnecessarily self-monitoring blood glucose levels despite this practice being recognized as a low-value service.

Liraglutide significantly reduces risk for major cardiac events in elderly patients with diabetes

A significant reduction in major cardiac events among elderly patients was seen in the liraglutide treatment group.

A Risk Prediction Tool for Hip Fracture in Type 2 Diabetes

A Risk Prediction Tool for Hip Fracture in Type 2 Diabetes

A hip fracture risk tool for patients with type 2 diabetes performed well in predicting incident hip fractures using readily available variables.

Hypertensive Disorders in Pregnancy, Postpartum BMI Linked to T2D Risk

Hypertensive Disorders in Pregnancy, Postpartum BMI Linked to T2D Risk

Postpartum women with an elevated BMI score and a history of hypertensive disorders during pregnancy have an increased risk of developing type 2 diabetes.

Type 2 Diabetes Linked to Colorectal Cancer Risk in Men

Type 2 Diabetes Linked to Colorectal Cancer Risk in Men

Type 2 diabetes (T2D) is associated with an increased risk for colorectal cancer (CRC), with the association significant for men only.

Normalized HbA1c Levels Facilitate Improved Neuropathy Outcomes in T2D

Normalized HbA1c Levels Facilitate Improved Neuropathy Outcomes in T2D

Normalized HbA1c levels facilitated improvement in neuropathy and nephropathy in type 2 diabetes of a short duration.

Serious Adverse Events Linked to SGLT2 Inhibitors

Serious Adverse Events Linked to SGLT2 Inhibitors

Compared with GLP-1 receptor agonists, the use of SGLT2 inhibitors is associated with an increased risk for diabetic ketoacidosis and lower limb amputation.

Skin Autofluorescence Predicts T2D, Heart Disease, Mortality

Skin Autofluorescence Predicts T2D, Heart Disease, Mortality

Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease (CVD), and mortality in the general population.

Impaired Glucose Metabolism May Affect Mood Stabilizer Response in Bipolar Disorder

Impaired Glucose Metabolism May Affect Mood Stabilizer Response in Bipolar Disorder

High blood sugar levels may put patients with bipolar disorder at risk of not responding to lithium and other mood stabilizer treatments.

Unhealthy Lifestyle and Rotating Night Shifts Put Nurses at Higher Risk for T2D

Unhealthy Lifestyle and Rotating Night Shifts Put Nurses at Higher Risk for T2D

Female nurses who frequently work rotating night shifts and adhere to an unhealthy lifestyle are at significantly greater risk of developing type 2 diabetes.

Cost-Related Insulin Underuse in Patients With Diabetes

Cost-Related Insulin Underuse in Patients With Diabetes

About one in four patients report cost-related insulin underuse, which is associated with poor glycemic control.

Endocrine Society: Policy and Practice Changes Necessary to Improve Access to Insulin

Endocrine Society: Policy and Practice Changes Necessary to Improve Access to Insulin

The rising cost of insulin has made it increasingly difficult for patients with diabetes to receive affordable, life-saving medication, especially patients from low-income backgrounds, patients with high deductibles, and uninsured patients.

Plasma Acylcarnitines May Indicate Risk for Type 2 Diabetes

Plasma Acylcarnitines May Indicate Risk for Type 2 Diabetes

Among individuals at a high risk for cardiovascular disease, a panel of short- and long-chain acylcarnitines was significantly associated with the incidence of type 2 diabetes.

Elevated Triglyceride Levels Affect Glycemic Control in Type 2 Diabetes

Elevated Triglyceride Levels Affect Glycemic Control in Type 2 Diabetes

Reducing triglyceride levels in patients with type 2 diabetes may help them attain more optimal glycemic control.

Sharp Increase in Projected Global Insulin Use From 2018 to 2030

Sharp Increase in Projected Global Insulin Use From 2018 to 2030

From 2018 to 2030, the insulin required to treat type 2 diabetes is expected to increase more than 20 percent.

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

The addition of ezetimibe to simvastatin reduced ischemic risk compared with placebo, with consistent relative risk reductions in patients with and without polyvascular disease.

ACC Releases Recommendations for Treatment of Patients With T2D and ASCVD

ACC Releases Recommendations for Treatment of Patients With T2D and ASCVD

The American College of Cardiology published an expert consensus statement regarding decision considerations for novel cardiovascular risk reduction therapies in patients with type 2 diabetes and atherosclerotic cardiovascular disease.

Lixisenatide Associated With Beneficial Renal Outcomes in Patients With T2D

Lixisenatide Associated With Beneficial Renal Outcomes in Patients With T2D

In patients with T2D and acute coronary syndrome, treatment with the short-acting glucagon-like peptide-1 (GLP-1) receptor agonist lixisenatide reduced urinary albumin-to-creatinine ratio.

Ketogenic Diet for the Management of T2D and Associated Long-Term Complications

Ketogenic Diet for the Management of T2D and Associated Long-Term Complications

With obesity reaching epidemic proportions, and its known association with many metabolic disorders such as type 2 diabetes, dyslipidemia, hypertension, and atherosclerosis, it is worthwhile to look at nutritional approaches to managing these chronic conditions.

Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

Linagliptin added to usual care compared with placebo added to usual care resulted in a noninferior risk for a composite cardiovascular or renal outcome over a median 2.2 years.

Exposure to Maternal Diabetes Increases Risk for ADHD in Offspring

Exposure to Maternal Diabetes Increases Risk for ADHD in Offspring

The 3 main types of diabetes during pregnancy were associated with offspring ADHD risk in a hierarchical order.

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

High Circulating Prolactin Concentrations May Lower Risk for Type 2 Diabetes

High circulating total prolactin concentrations may be linked with a lower risk for type 2 diabetes in women.

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

Dapagliflozin Lowers Heart Failure Hospitalization Rates in High-Risk Patients With Diabetes

Dapagliflozin was not associated with either a higher or lower rate of MACE compared with placebo in patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease.

Direct-Acting Antiviral Therapy Reduced Risk for Incident T2D in Patients With Hepatitis C Infection

Direct-Acting Antiviral Therapy Reduced Risk for Incident T2D in Patients With Hepatitis C Infection

The study compared US administrative claims data of HCV patients with ≥12 weeks of dispensed DAA therapy (N = 17,848) to untreated HCV patients with follow-up data (N = 108,350).

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

ADA Issues Position Statement on Comprehensive Care for Pediatric T2D

The American Diabetes Association issued a position statement outlining the recognition, management, and prevention of T2D in the pediatric population.

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Peer Support Reduces Hospitalizations in People With Diabetes and Depression

Patients with diabetes and depressive symptoms who received community-based peer support for diabetes management reported less frequent acute care visits and hospitalizations than patients with diabetes without depressive symptoms.

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D

Postprandial hypoglycemia may occur after Roux-en-Y gastric bypass in patients with type 2 diabetes, independent from diabetes remission.

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization in T2D

Empagliflozin Effectively Reduces Risk for Heart Failure Hospitalization in T2D

Approximately 50% of deaths in people with type 2 diabetes worldwide, and approximately two-thirds of deaths in people with type 2 diabetes in the US are caused by cardiovascular disease.

Acute and Persistent Prothrombic Effects Observed With Antecedent Hypoglycemia in T2D

Acute and Persistent Prothrombic Effects Observed With Antecedent Hypoglycemia in T2D

Hypoglycemia was associated with early and late prothrombotic changes in the fibrin network in individuals with type 2 diabetes.

Insulins

Insulin products chart with pharmacokinetic properties.

Insulin Administration

Insulin preparations categorized by rapid-, short-, intermediate- and long-acting. Information such as the route, administration as well as the mixing of insulins is provided.

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

Patients With T2D and Sickle-Cell Trait at Higher Risk for Complications

Diabetic complications were more prevalent in patients with both sickle-cell trait and T2D than in patients with T2D alone.

AHA, ADA Announce Joint Education Initiative to Reduce CVD Deaths in T2D

AHA, ADA Announce Joint Education Initiative to Reduce CVD Deaths in T2D

The ADA and the AHA launch a long-term awareness and education initiative for the prevention of deaths due to cardiovascular complications in patients with T2D.

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Type 2 Diabetes May Have Adverse Effect on Parkinson Disease Symptoms, Outcomes

Patients with both Parkinson disease and type 2 diabetes were more likely to have cardiovascular comorbidities than those with only Parkinson disease.

Risk for T2D Increases Following Total or Partial Colectomy

Risk for T2D Increases Following Total or Partial Colectomy

Patients who have the entire or left side of the colon removed show increased risk for developing type 2 diabetes in the 18 years following surgery.

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

Plant-Based Diets Beneficial for Adults With Type 2 Diabetes

For adults with type 2 diabetes, plant-based diets can improve psychological health, quality of life, hemoglobin A1c levels, and weight.

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Lipidome Profiles Stratify Risk for Type 2 Diabetes

Early detection of lipidome characteristics could help identify the early onset of type 2 diabetes.

Diabetes Education Week 2018: Patient Resources for Your Practice

Diabetes Education Week 2018: Patient Resources for Your Practice

In recognition of National Diabetes Education Week, Endocrinology Advisor compiled a list of resources to assist clinicians when educating patients with diabetes about their condition.

Intensive BP, Lipid Control in T2D May Increase Risk for Adverse Kidney Events

Intensive BP, Lipid Control in T2D May Increase Risk for Adverse Kidney Events

Intensive BP control and fenofibrate use in patients with T2D who are at high risk for CVD may increase the risk for adverse kidney events.

Another Antihypertensive Recalled Due to Potentially Carcinogenic Impurity

Another Antihypertensive Recalled Due to Potentially Carcinogenic Impurity

The impurity was identified following laboratory testing conducted by the Food and Drug Administration (FDA); this is the first non-valsartan product that the Agency has found to contain NDEA.

Exposure to Ready-to-Eat Food Outlets Associated With Risk for Type 2 Diabetes

Exposure to Ready-to-Eat Food Outlets Associated With Risk for Type 2 Diabetes

Access to ready-to-eat outlets that sell food for instant consumption is associated with greater risk for type 2 diabetes.

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

Bardoxolone Methyl Leads to Weight Loss in T2D with Concurrent Chronic Kidney Disease

Treatment with bardoxolone methyl resulted in significant weight loss and showed no evidence of muscle wasting in patients with type 2 diabetes and stage IV chronic kidney disease.

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

Canagliflozin Approved to Reduce Risk for Cardiovascular Events in T2D

The effect of Invokana on CV risk was evaluated in the CANVAS (CANagliflozin cardioVascular Assessment Study) Program in >10,000 adults with T2D who had established CV disease or were at risk for CV disease with ≥2 risk factors.

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, Obesity, Hypertriglyceridemia Negatively Related to CAN in T2D

Hyperglycemia, obesity, and hypertriglyceridemia in type 2 diabetes are negatively related to indices of cardiovascular autonomic neuropathy.

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Early Natural Menopause Linked to Life Expectancy, Years With T2D

Compared with women who experience normal or late menopause, women who experience early natural menopause have a shorter life expectancy and spend fewer years without type 2 diabetes.

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

Dual GIP, GLP-1 Receptor Agonist Effective for Weight Loss, Glucose Control in T2D

LY3298176, a dual GIP and GLP-1 receptor agonist, showed significantly better efficacy than dulaglutide with regard to glucose control and weight loss in type 2 diabetes.

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

Type 2 Diabetes an Independent Risk Factor for Coronary Artery Disease

Type 2 diabetes is an independent risk factor for sudden cardiac arrest and death in patients with coronary artery disease with preserved ejection fraction.

Biomarkers of Dairy Fat Consumption Inversely Associated With Type 2 Diabetes Risk

Biomarkers of Dairy Fat Consumption Inversely Associated With Type 2 Diabetes Risk

Researchers found that higher levels of fatty acid biomarkers 15:0, 17:0, and trans-16:1n7 were inversely associated with risk for T2D.

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

Gastric Banding vs Metformin for Improved Insulin Sensitivity in Mild T2D

Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.

Incretin-Based Therapies Not Associated With New-Onset Depression, Self-Harm in T2D

Incretin-Based Therapies Not Associated With New-Onset Depression, Self-Harm in T2D

There was not a clinically relevant association between DPP-4 inhibitors or GLP-1 receptor agonists and depression or self-harm in type 2 diabetes.

Glucose Dysregulation Begins Years Before Diabetes Diagnosis

Glucose Dysregulation Begins Years Before Diabetes Diagnosis

Individuals who develop diabetes or prediabetes have elevated fasting plasma glucose (FPG) at least 10 years before diagnosis.

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Severity of Metabolic Syndrome Indicates Risk for T2D, CVD in Prediabetes Treatment

Researchers analyzed how improvements in metabolic syndrome may impact the risk of developing type 2 diabetes and cardiovascular disease in patients with prediabetes.

Bone-Derived Factors in the Treatment of Diabetes

Bone-Derived Factors in the Treatment of Diabetes

A growing body of research highlights the important role of bone in glucose metabolism.

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

For patients with severe obesity and type 2 diabetes, bariatric surgery is associated with a lower risk for macrovascular outcomes compared with not undergoing surgery.

Periodic Fasting May Reduce Medication Use in T2D

Periodic Fasting May Reduce Medication Use in T2D

Medically supervised, therapeutic fasting regimens can help reverse type 2 diabetes (T2D) and minimize the need for pharmacological interventions.

Cost a key consideration of WHO guidelines for diabetes treatment intensification

WHO guidelines recommend selecting sulfonylureas as the single best second-line agent for Type 2 Diabetes Mellitus (T2DM) patients.

Fasting Glycemic Variability Indicates Increased Risk for Type 2 Diabetes

Fasting Glycemic Variability Indicates Increased Risk for Type 2 Diabetes

Greater variation of fasting plasma glucose over time is associated with an increased risk of developing type 2 diabetes.

Sitagliptin Provides Better Glycemic Control Than Dapagliflozin in T2D With Renal Impairment

Sitagliptin Provides Better Glycemic Control Than Dapagliflozin in T2D With Renal Impairment

Study results indicated that sitagliptin showed greater glycemic efficacy than dapagliflozin treatment.

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

Diabetes Associated With Elevated Risk for Arthritis, Osteoporosis

Osteoarthritis was the most common form of arthritis in patients with diabetes but rheumatoid arthritis had the most pronounced association with diabetes.

Cardiovascular Outcomes for Albiglutide Treatment in T2D

Cardiovascular Outcomes for Albiglutide Treatment in T2D

For patients with type 2 diabetes and existing cardiovascular disease, albiglutide results in fewer cardiovascular events.

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

Empagliflozin Treatment Positively Impacts Life Expectancy in T2D With CVD

For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

Risk for Type 2 Diabetes, Cardiovascular Disease Elevated in Patients With Psoriatic Arthritis

Risk for type 2 diabetes, ischemic heart disease, and peripheral vascular disease was elevated among patients with psoriatic arthritis compared with the general population.

Lorcaserin Reduces Risk for Incident Diabetes in Patients With Prediabetes

Lorcaserin Reduces Risk for Incident Diabetes in Patients With Prediabetes

In this new analysis, researchers looked at the long-term effects of the drug on diabetes prevention and remission in these patients.

Updated ADA, EASD Consensus Guidelines for Managing Hyperglycemia in T2D

Updated ADA, EASD Consensus Guidelines for Managing Hyperglycemia in T2D

Recommendations in the report highlight the importance of patient-centered decision making for glycemic management and improving diet and exercise for patients with T2D.

FDA Issues Safety Communication Regarding Pen Needle Use

FDA Issues Safety Communication Regarding Pen Needle Use

Standard pen needles have an outer cover and removable inner needle cover, while safety pen needles have an outer cover and a fixed inner needle shield that is not removed before an injection.

Obesity Reduces Number of Disease-Free Years Regardless of Lifestyle

Obesity Reduces Number of Disease-Free Years Regardless of Lifestyle

Obesity is associated with loss of disease-free years irrespective of position in the social hierarchy and lifestyle.

Basal Insulin Combination Therapies With Vildagliptin or Lixisenatide Equally Effective for T2D

Basal Insulin Combination Therapies With Vildagliptin or Lixisenatide Equally Effective for T2D

Combination therapies of basal insulin with either vildagliptin or lixisenatide are similarly effective at producing glycemic control improvements.

Genetics May Identify Type 2 Diabetes Subtypes

Genetics May Identify Type 2 Diabetes Subtypes

Clusters of type 2 diabetes loci and traits have been identified.

Sleep Disturbances Affect Glycemic Control in Patients With Type 2 Diabetes

Sleep Disturbances Affect Glycemic Control in Patients With Type 2 Diabetes

Findings from the study showed a graded association between shorter average sleep duration and higher HbA1c concentrations among participants with diabetes.

Replacing Red Meat With Poultry or Fish Lowers Type 2 Diabetes Risk

Replacing Red Meat With Poultry or Fish Lowers Type 2 Diabetes Risk

Substituting processed red meat with poultry or fish and replacing total red meat with fish were associated with a lowered risk for type 2 diabetes.

Investigating the Link Between Atrial Fibrillation and Type 2 Diabetes

Investigating the Link Between Atrial Fibrillation and Type 2 Diabetes

Compared with the general population, patients with type 2 diabetes are at a 35% to 60% greater risk for atrial fibrillation.

CPAP Therapy for Sleep Apnea Does Not Improve Diabetic Macular Edema in T2D

CPAP Therapy for Sleep Apnea Does Not Improve Diabetic Macular Edema in T2D

Continuous positive airway pressure for obstructive sleep apnea in patients with type 2 diabetes offered no improvement in visual acuity compared with usual care alone.

Time in Range According to CGM Associated With Diabetic Retinopathy

Time in Range According to CGM Associated With Diabetic Retinopathy

Investigators assessed the time in range according to a continuous glucose monitor and the risk for diabetic retinopathy.

Effect of Baseline Characteristics on Glycemic Control With Insulin Glargine in T2D

Effect of Baseline Characteristics on Glycemic Control With Insulin Glargine in T2D

Investigators examined the effects of insulin glargine 300 U/mL vs insulin glargine 100 U/mL on glycated hemoglobin, hypoglycemia, and body weight change.

Pharmacotherapy Personalization May Optimize Outcomes for Type 2 Diabetes

Pharmacotherapy Personalization May Optimize Outcomes for Type 2 Diabetes

Investigators examined patient factors that affect the use of diabetes medication in patients with type 2 diabetes.

Muscle Cell Profiles Relate to Exercise Response Variation in Type 2 Diabetes

Muscle Cell Profiles Relate to Exercise Response Variation in Type 2 Diabetes

Researchers aimed to determine whether variations in phosphocreatine recovery rates were marked by distinct epigenomic muscle profiles that could be seen prior to training.

High Prevalence of Obstructive Sleep Apnea Syndrome May Favor Screening in Diabetes

High Prevalence of Obstructive Sleep Apnea Syndrome May Favor Screening in Diabetes

The high prevalence of obstructive sleep apnea syndrome in both type 1 and type 2 diabetes may favor screening in these patients.

Update on the T2D-Dementia Link: Interview With Experts

Update on the T2D-Dementia Link: Interview With Experts

Endocrinology Advisor interviewed experts to explore mechanisms, clinical implications, and research needs pertaining to the diabetes-dementia link.

Estimated Prevalence of Diabetes in the United States

Estimated Prevalence of Diabetes in the United States

The prevalence of type 1 and type 2 diabetes is 0.5 and 8.5 percent, respectively, among U.S. adults.

Lower Hypoglycemia Risk, Greater Weight Loss With SGLT2 Inhibitor, Sulfonylurea in T2D

Lower Hypoglycemia Risk, Greater Weight Loss With SGLT2 Inhibitor, Sulfonylurea in T2D

SGLT-2i exhibited superior effects in terms of weight loss and did not increase the risk for hypoglycemia in dual therapy with sulfonylurea.

LVAD in Heart Failure Linked to Improved Glycemic Control

LVAD in Heart Failure Linked to Improved Glycemic Control

HbA1c levels following left ventricular assist device implantation were statistically significantly lower than before surgery.

Collaborative Care Improves Depression but Not Incident Diabetes

Collaborative Care Improves Depression but Not Incident Diabetes

Investigators examined the effects of a 12-month collaborative care program for patients with late-life depression on the 9-year incidence of diabetes in older individuals.

Association Between Urine Complement Proteins and Kidney Disease, Mortality in T2D

Association Between Urine Complement Proteins and Kidney Disease, Mortality in T2D

Researchers suggest complement pathway activation plays a role in diabetic kidney disease progression in people with proteinuria.

Rates of Incident Type 2 Diabetes in Chronic Kidney Disease

Rates of Incident Type 2 Diabetes in Chronic Kidney Disease

Investigators examined the rates and risk factors for type 2 diabetes in individuals with chronic kidney disease.

Availability and Affordability of Diabetes Medication Worldwide

Availability and Affordability of Diabetes Medication Worldwide

The affordability and availability of diabetes medications across multiple regions of the word were examined, along with the effects on the use of medications.

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive Blood Pressure Therapy Lowers Cardiovascular Risk in Diabetes

Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher levels of aldosterone are associated with insulin resistance and incident type 2 diabetes among multiethnic individuals.

Early Treatment Intensification and Faster Glycemic Control in T2D

Early Treatment Intensification and Faster Glycemic Control in T2D

Individuals with type 2 diabetes intensifying within 12 months of the index date had a significantly shorter median time from intensification to glycemic control.

Comparing Second-Generation Basal Insulin Analogs for Type 2 Diabetes

Comparing Second-Generation Basal Insulin Analogs for Type 2 Diabetes

Researchers concluded noninferiority between two basal insulin analogs after comparing safety and efficacy end points.

Comparing Antidiabetic Drug Classes for Risk of Heart Failure

Comparing Antidiabetic Drug Classes for Risk of Heart Failure

The authors searched for randomized placebo-controlled trials (December 1, 2008 to November 24, 2017) involving 3 pharmacologic classes of antidiabetic medications to compare the effects of these agents on the risk of hospitalization for HF in T2DM patients.

Widespread Statin Use Not Recommended in Old, Very Old

Widespread Statin Use Not Recommended in Old, Very Old

Statin use is not associated with reduced risk of atherosclerotic cardiovascular disease or all-cause mortality among older adults without type 2 diabetes.

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

Investigators used data from the National Health Interview Survey and follow-up mortality data to estimate trends and disparities in CVD.

Comparing Efficacies of Second-Line Treatments in Type 2 Diabetes

Comparing Efficacies of Second-Line Treatments in Type 2 Diabetes

Researchers conducted a retrospective analysis to determine whether second-line treatment options sulfonylureas, DPP-4 inhibitors, and thiazolidinediones were associated with reduced HbA1c levels.

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