Type 1 Diabetes

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

For youth with type 1 diabetes, disordered eating behaviors are associated with higher hemoglobin A1c but not with measures of glycemic variability.

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

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Higher rates of operative delivery and falling gestational age at delivery suggest that this is either reflected by, or despite, increasing obstetric intervention.

Improved islet encapsulation device for the treatment of type 1 diabetes [PreClinical]

A device for islet transplantation for type 1 diabetes was designed and demonstrated to be safe and retrievable in animal models. When tested in mice and dogs, this device successfully reduced glucose levels.

Genetic Variants Linked to Phenotypic Heterogeneity of Type 1 Diabetes

Genetic Variants Linked to Phenotypic Heterogeneity of Type 1 Diabetes

Transcription factor 7 like 2 genetic variants contribute to phenotypic heterogeneity of type 1 diabetes.

T1D, T2D May Have Protective Effects on Risk for Migraine

T1D, T2D May Have Protective Effects on Risk for Migraine

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Results from a study investigating diabetes and migraine in the Norwegian population show that type 1 and type 2 diabetes were significantly associated with a decreased risk for migraine.

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Patients with diabetes had higher rates for all 19 infection categories with the highest incidence rate ratios seen for bone and joint infections, sepsis, and cellulitis.

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

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Weaning to a hydrolyzed formula did not reduce the risk of type 1 diabetes in children with an increased disease risk.

Trends in CVD, Risk Factors, and Medications in Children With T1D

Trends in CVD, Risk Factors, and Medications in Children With T1D

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Children with T1D had statistically significantly higher prevalence rates of hypertension, hypercholesterolemia, and used more CV medication compared with a matched diabetes-free reference cohort in the period after the onset of diabetes.

Safety of Novel Soluble Glucagon Analog for Severe Hypoglycemia in T1D Evaluated

Safety of Novel Soluble Glucagon Analog for Severe Hypoglycemia in T1D Evaluated

Dasiglucagon is well-tolerated and is associated with an early pharmacodynamic response similar to that of GlucaGen for severe hypoglycemia.

Alum-Formulated Glutamate Decarboxylase Injections Safe for Prediabetic Children

Alum-Formulated Glutamate Decarboxylase Injections Safe for Prediabetic Children

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Study evaluated the safety and efficacy of autoantigen-specific therapy with alum-formulated glutamate decarboxylase in nondiabetic children with multiple islet autoantibodies.

Cumulative Risk of ESRD Decreased Over Time for T1D

Cumulative Risk of ESRD Decreased Over Time for T1D

The cumulative risk of end-stage renal disease among patients with type 1 diabetes has declined over time in Finland.

Depression and Severe Dysglycemia Associated Bidirectionally in T1D

Depression and Severe Dysglycemia Associated Bidirectionally in T1D

For patients with type 1 diabetes, there is a bidirectional association between depression and severe hypoglycemia and hyperglycemia.

Increased Risk of Type 1 Diabetes in Children With Asthma

Increased Risk of Type 1 Diabetes in Children With Asthma

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A previous diagnosis of asthma increases the risk for subsequent type 1 diabetes by 41%, but a previous diagnosis of type 1 diabetes decreases the risk of subsequent asthma by 18%.

Does Genetic Susceptibility Lead to Late-Onset Type 1 Diabetes?

Does Genetic Susceptibility Lead to Late-Onset Type 1 Diabetes?

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In older adults, in whom T1D is rare, patients with diabetes who are positive for autoantibodies are as likely to be false positive with T2D as true positive with T1D.

Corticosteroids Linked With Risk for Fracture, VTE, Sepsis in Diabetes

Corticosteroids Linked With Risk for Fracture, VTE, Sepsis in Diabetes

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Corticosteroids should be used with caution in patients with diabetes and mitigating factors should be considered.

Vascular Endothelial Dysfunction Involved in Hypertension Development in T1D

Vascular Endothelial Dysfunction Involved in Hypertension Development in T1D

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A life-course study evaluated the contribution of vascular endothelial dysfunction and inflammation to the development of hypertension in type 1 diabetes.

Effect of SGLT2 Inhibitors on Early Metabolic Decompensation in T1D

Effect of SGLT2 Inhibitors on Early Metabolic Decompensation in T1D

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Patients with T1D are not susceptible to accelerated lipolysis and ketogenesis, despite the reduction in overnight basal insulin doses during SGLT2i treatment.

Real-Time Continuous Glucose Monitoring Beneficial But Challenges Remain

Real-Time Continuous Glucose Monitoring Beneficial But Challenges Remain

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Although sharing of real-time continuous glucose monitoring data can create tension between patients with type 1 diabetes and family members, it can also facilitate greater empowerment and perceptions of safety among both patients and their caregivers.

Identifying Risk for Microalbuminuria in Children With Type 1 Diabetes

Identifying Risk for Microalbuminuria in Children With Type 1 Diabetes

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Study sought to evaluate whether baseline autonomic dysfunction was predictive of future increases in urine albumin-creatinine ratio in pediatric patients with type 1 diabetes.

Oral Insulin Not a Reliable Preventive Strategy for Type 1 Diabetes

Oral Insulin Not a Reliable Preventive Strategy for Type 1 Diabetes

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Investigators sought to delay or prevent the onset of type 1 diabetes by administering a once-daily oral insulin tablet.

Psychosocial Benefits of a Bihormonal Bionic Pancreas System in T1D

Psychosocial Benefits of a Bihormonal Bionic Pancreas System in T1D

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Participants reported improvements in many psychosocial variables associated with using an automated bihormonal bionic pancreas system relative to self-management of diabetes using their own insulin pump.

New Report Standardizes Clinically Meaningful T1D Outcomes Beyond HbA1c Testing

New Report Standardizes Clinically Meaningful T1D Outcomes Beyond HbA1c Testing

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Representatives from multiple associations and societies have issued a new report standardizing clinically meaningful outcome measures for type 1 diabetes, beyond using HbA1c testing.

Effects of Peer Influence in Adolescents With Type 1 Diabetes

Effects of Peer Influence in Adolescents With Type 1 Diabetes

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Study underscores the need to focus on the peer context to understand the functioning of youths with type 1 diabetes.

Improving Daily Glucose Monitoring in Adolescents With Incentive-Based Approach

Improving Daily Glucose Monitoring in Adolescents With Incentive-Based Approach

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Incentive-based approaches developed to improve daily adherence to a single behavioral process, such as blood glucose monitoring in adolescents, may not be as effective as multicomponent interventions that address emotional, social, and family processes of diabetes self-management.

Remotely Connected Diabetes System Improves Glycemic Control in Insulin-Treated Diabetes

Remotely Connected Diabetes System Improves Glycemic Control in Insulin-Treated Diabetes

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A remotely connected diabetes management system increased patent satisfaction and improved glycemic control in patients with insulin-treated diabetes.

Effect of Prior Glucose Monitoring on Glycemic Outcomes With a Hybrid Closed-Loop System

Effect of Prior Glucose Monitoring on Glycemic Outcomes With a Hybrid Closed-Loop System

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Patients with prior experience using a continuous glucose monitoring system may benefit from the MiniMed 670G HCL system therapy.

Utilizing Trend Arrow Data in CGM Systems to Manage Diabetes in Children

Utilizing Trend Arrow Data in CGM Systems to Manage Diabetes in Children

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Recommendations for utilizing trend arrow data in a mobile continuous glucose monitoring system were recently issued for pediatric patients with type 1 diabetes.

Leptin Levels Associated With Risk for Preeclampsia in Women With T1D

Leptin Levels Associated With Risk for Preeclampsia in Women With T1D

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Investigators believe that circulating adipokines may be associated with the development of preeclampsia in women with type 1 diabetes in the first trimester.

Improved Neonatal Outcomes With Continuous Glucose Monitoring in T1D

Improved Neonatal Outcomes With Continuous Glucose Monitoring in T1D

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Investigators assess maternal hyperglycemia exposure to fetus with neonatal health outcomes.

Childhood Antibiotic Use Not Linked to Islet or Celiac Disease Autoimmunity

Childhood Antibiotic Use Not Linked to Islet or Celiac Disease Autoimmunity

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Islet and celiac disease autoimmunity were defined as a positive test result for islet or tissue transglutaminase autoantibodies at 2 clinic visits at least 3 months apart.

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