Type 1 Diabetes

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

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Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

For patients with type 1 diabetes, artificial pancreas treatment is efficacious, increasing the proportion of time spent in the near normoglycemic range.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

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Awareness of ASD and its manifestations and comorbidities remain imperative in the treatment of T1D, as both conditions require long-term medical follow-up to continue improving diabetes care and metabolic control outcomes.

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

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The type of sciatic nerve lesions observed in patients with diabetic peripheral neuropathy was found to differ in type 1 and type 2 diabetes.

Pharmacists Can Help With Diabetes Management via Telemedicine

Pharmacists Can Help With Diabetes Management via Telemedicine

Telemedicine could provide real-time feedback loop and allow pharmacists to help patients self-manage.

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

For adults with type 1 diabetes with suboptimal control despite using multiple insulin injections, continuous glucose monitoring seems cost-effective, with improved glucose control.

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Young adults with type 1 diabetes have altered neural responses during working memory processing.

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Researchers conducted a systematic literature review to identify studies on cognitive function in children with type 1 diabetes.

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

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IPITA and EPITA held a workshop to develop consensus for a joint statement on the definition of function and failure of current and future forms of β-cell replacement therapy.

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

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Anti-osteoporotic medications (mainly bisphosphonates) seem to equally prevent bone loss, especially in the lumbar spine, in patients with diabetes compared with patients without diabetes.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

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Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

There are significant improvements in health-related quality of life following islet transplantation in patients with type 1 diabetes complicated by severe hypoglycemia.

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

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Researchers assessed the safety and accuracy of an implantable continuous glucose measurement in adults diagnosed with type 1 and type 2 diabetes.

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

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Study provided evidence of significant differences in median serum concentrations of circulating adipose-related inflammatory biomarkers across the main diabetes types.

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

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The FDA reviewed data for the device through the de novo premarket review pathway, a regulatory pathway for novel, low-to-moderate-risk devices that are not substantially equivalent to an already legally marketed device.

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

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Sanofi announced that the Food and Drug Administration (FDA) has approved Toujeo (insulin glargine 300 Units/mL) Max SoloStar, a long-acting insulin pen that holds 900 Units of Toujeo and provides up to 160 Units/mL per injection.

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

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Researchers assessed whether alcohol intake affects response to glucagon in individuals with type 1 diabetes.

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

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The NDA is based on results from a large placebo-controlled, phase 3 trial that included 1402 patients with type 1 diabetes who were receiving insulin therapy.

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

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Researchers assessed differences in glycemic control, major cardiovascular risk factors, diabetes-related complications, sexual dysfunction prevalence, and endothelial function in young men and women with type 1 diabetes.

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

For pregnant women with type 1 diabetes, a closed-loop system is associated with comparable glucose control and significantly less hypoglycemia than sensor-augmented pump therapy.

MiniMed 670G System Improves Glycemic Outcomes in Children With T1D

MiniMed 670G System Improves Glycemic Outcomes in Children With T1D

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Research findings indicate improved glycemic outcomes in children with T1D using the MiniMed 670G system, similar to those observed for adolescents and adults.

Minority Youths With T1D Have Poor Prognostic Factors, More Complications

Minority Youths With T1D Have Poor Prognostic Factors, More Complications

Researchers assessed racial and ethnic differences in outcomes among patients in the first 3 years following diagnosis of type 1 diabetes.

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

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Study found that the absence of proliferative diabetic retinopathy in those with stage 3b chronic kidney disease is associated with a lower prevalence of cardiovascular disease in patients with long duration of type 1 diabetes.

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

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Study suggests that single-hormone artificial pancreas systems may be sufficient for overnight control even in a high-risk group of hypoglycemia-unaware participants with documented nocturnal hypoglycemia.

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

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High-quality studies are needed to determine whether tight intrapartum glycemic control is superior to more relaxed glycemic targets intrapartum for women with diabetes in pregnancy.

Parental History of T1D May Increase Risk for ADHD in Offspring

Parental History of T1D May Increase Risk for ADHD in Offspring

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Researchers calculated the hazard ratio of ADHD in offspring of patients with type 1 diabetes compared with the general population.

Growth and Development Differences During Puberty in Children With T1D

Growth and Development Differences During Puberty in Children With T1D

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Study showed gender-discordant metabolic impairment during puberty that was correlated with peak growth velocity in boys, but not in girls.

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

For youth with type 1 diabetes, disordered eating behaviors are associated with higher hemoglobin A1c but not with measures of glycemic variability.

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

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Higher rates of operative delivery and falling gestational age at delivery suggest that this is either reflected by, or despite, increasing obstetric intervention.

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