Type 1 Diabetes

FDA Committee Votes on Oral T1D Treatment Sotagliflozin

FDA Committee Votes on Oral T1D Treatment Sotagliflozin

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The FDA takes the advice of the panel into consideration when making decisions, however it is not bound by their recommendations.

Is the MiniMed 670G System Safe for Children With Type 1 Diabetes?

Is the MiniMed 670G System Safe for Children With Type 1 Diabetes?

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The MiniMed 670G system is effective and safe for in-home use by children with type 1 diabetes.

Diabetic Ketoacidosis May Affect Brain Development in Children With T1D

Diabetic Ketoacidosis May Affect Brain Development in Children With T1D

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In young children with type 1 diabetes, even a single episode of moderate/severe diabetic ketoacidosis can have long-term effects on the developing brain.

Maternal Thyroid Function in Pregnancy Linked to Childhood Risk for Disease

Maternal Thyroid Function in Pregnancy Linked to Childhood Risk for Disease

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Maternal Graves disease and Hashimoto disease during pregnancy increases childhood risk for type 1 diabetes and schizophrenia, respectively.

Cerebral Small Vessel Disease More Common in Individuals With T1D vs General Population

Cerebral Small Vessel Disease More Common in Individuals With T1D vs General Population

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Cerebral small vessel disease (SVD) is more commonly observed in individuals with type 1 diabetes (T1D) compared with the general population.

RAAS Activation Linked to Vascular Stiffening in T1D With Proliferative Retinopathy

RAAS Activation Linked to Vascular Stiffening in T1D With Proliferative Retinopathy

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In patients with long-standing T1D and proliferative diabetic retinopathy, renin-angiotensin-aldosterone system activation may be associated with vascular stiffening.

Head-to-Head Comparison of Professional vs Personal CGM Systems in T1D

Head-to-Head Comparison of Professional vs Personal CGM Systems in T1D

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Professional and personal continuous glucose monitoring systems exhibit similar accuracy in both inpatient and home settings, with both having lower sensor performance during hypoglycemic episodes.

ADA's 2019 Standards of Medical Care in Diabetes Focus on Patient-Centered Care

ADA's 2019 Standards of Medical Care in Diabetes Focus on Patient-Centered Care

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The ADA published its 2019 Standards of Medical Care in Diabetes, an evidence-based document intended to provide clinicians, patients, and other stakeholders in the diabetes treatment landscape with up-to-date recommendations.

Clinical Indicators of Risk for Addison Disease in Patients With T1D

Clinical Indicators of Risk for Addison Disease in Patients With T1D

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Treatment of thyroid disease, severe infections, glucagon prescriptions, and diabetic retinopathy occur more frequently in individuals with type 1 diabetes who are subsequently diagnosed with Addison disease.

Fear Impacts Quality of Life for Young Adults With Type 1 Diabetes

Fear Impacts Quality of Life for Young Adults With Type 1 Diabetes

Fear of complications and frustration at the amount of time required to manage type 1 diabetes impact the quality of life of young adults with the disease.

Cost-Related Insulin Underuse in Patients With Diabetes

Cost-Related Insulin Underuse in Patients With Diabetes

About one in four patients report cost-related insulin underuse, which is associated with poor glycemic control.

Endocrine Society: Policy and Practice Changes Necessary to Improve Access to Insulin

Endocrine Society: Policy and Practice Changes Necessary to Improve Access to Insulin

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The rising cost of insulin has made it increasingly difficult for patients with diabetes to receive affordable, life-saving medication, especially patients from low-income backgrounds, patients with high deductibles, and uninsured patients.

Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases

Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases

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Type 1 diabetes predisposes children and adults to autoimmune diseases, which can impair glucose metabolism and interfere with insulin therapy.

Exposure to Maternal Diabetes Increases Risk for ADHD in Offspring

Exposure to Maternal Diabetes Increases Risk for ADHD in Offspring

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The 3 main types of diabetes during pregnancy were associated with offspring ADHD risk in a hierarchical order.

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

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Pregnant women with T1D who received MDI therapy had a larger decrease in HbA1c levels and were less likely to report gestational hypertension, neonatal hypoglycemia, and NICU admissions than women who used insulin pump therapy during pregnancy.

Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes

Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes

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After 52 weeks, dapagliflozin was well tolerated and led to a clinically relevant improvement in glycemic control and weight loss without additional risk for hypoglycemia.

Hypoglycemia Following Antifungal Treatment in Patient With Type 1 Diabetes

Hypoglycemia Following Antifungal Treatment in Patient With Type 1 Diabetes

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"This is the first report of decreased insulin requirements in a patient with [T1D] correlating with micafungin administration," noted the authors.

Diabetes Education Week 2018: Patient Resources for Your Practice

Diabetes Education Week 2018: Patient Resources for Your Practice

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In recognition of National Diabetes Education Week, Endocrinology Advisor compiled a list of resources to assist clinicians when educating patients with diabetes about their condition.

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

Dose-Dependent Relationship Between Smoking and Cardiovascular Complications in T1D

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There is a dose-dependent association between smoking and coronary heart disease in patients with type 1 diabetes.

Bacillus Calmette-Guerin Vaccination Lowers HbA1c in Type 1 Diabetes

Bacillus Calmette-Guerin Vaccination Lowers HbA1c in Type 1 Diabetes

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Bacillus Calmette-Guerin vaccination impacted blood sugar levels in T1D by causing a systemic shift in glucose metabolism from oxidative phosphorylation to aerobic glycolysis.

Bone-Derived Factors in the Treatment of Diabetes

Bone-Derived Factors in the Treatment of Diabetes

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A growing body of research highlights the important role of bone in glucose metabolism.

Maternal Gluten Intake Associated With Risk for Type 1 Diabetes in Offspring

Maternal Gluten Intake Associated With Risk for Type 1 Diabetes in Offspring

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There was an association between high maternal intake of gluten and an elevated risk for type 1 diabetes for the child.

Exercise After Overnight Fasting Stabilizes Glucose Levels in Type 1 Diabetes

Exercise After Overnight Fasting Stabilizes Glucose Levels in Type 1 Diabetes

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The effect of high-intensity interval training with a bout of moderate-intensity continuous training on glucose levels was examined in T1D.

Positive Results for Empagliflozin in Type 1 Diabetes Trials

Positive Results for Empagliflozin in Type 1 Diabetes Trials

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The EASE Phase 3 program included 2 double-blind, placebo-controlled trials investigating the efficacy and safety of empagliflozin as an adjunct to insulin therapy in adults with type 1 diabetes.

Elevated HbA1c After Onset of T1D Predicts Psychiatric Comorbidity

Elevated HbA1c After Onset of T1D Predicts Psychiatric Comorbidity

High average glycated hemoglobin levels during the first two years after type 1 diabetes onset predict higher risk for psychiatric diagnoses.

Better Glycemic Control With Closed-Loop Insulin Delivery

Better Glycemic Control With Closed-Loop Insulin Delivery

For patients with suboptimally controlled type 1 diabetes, day-and-night hybrid closed-loop insulin delivery improves glucose control compared with sensor-augmented pump therapy.

FDA Issues Safety Communication Regarding Pen Needle Use

FDA Issues Safety Communication Regarding Pen Needle Use

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Standard pen needles have an outer cover and removable inner needle cover, while safety pen needles have an outer cover and a fixed inner needle shield that is not removed before an injection.

Effects of Fixed-Ratio Pramlintide and Insulin on Postprandial Hyperglycemia in T1D

Effects of Fixed-Ratio Pramlintide and Insulin on Postprandial Hyperglycemia in T1D

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Coadministration of 24 hours of fixed-ratio pramlintide and regular human insulin improves postprandial hyperglycemia and glycemic variability in patients with type 1 diabetes.

Investigating the Link Between Atrial Fibrillation and Type 2 Diabetes

Investigating the Link Between Atrial Fibrillation and Type 2 Diabetes

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Compared with the general population, patients with type 2 diabetes are at a 35% to 60% greater risk for atrial fibrillation.

Estimated Prevalence of Diabetes in the United States

Estimated Prevalence of Diabetes in the United States

The prevalence of type 1 and type 2 diabetes is 0.5 and 8.5 percent, respectively, among U.S. adults.

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