Type 1 Diabetes

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Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Chronic Kidney Disease More Common in Type 2 Diabetes Than in Type 1 Diabetes

Investigators examined the prevalence of chronic kidney disease in adults with type 1 diabetes compared with type 2 diabetes.

Preventing Hypoglycemia During Exercise in Type 1 Diabetes on CSII

Preventing Hypoglycemia During Exercise in Type 1 Diabetes on CSII

Reducing basal insulin delivery by 50%-80% 90 minutes before aerobic exercise better prevents hypoglycemia risk vs basal suspension or disconnection at exercise onset.

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

Implantable Continuous Glucose Monitoring Device Safe, Effective for Adolescents

The safety assessment included incidence of insertion or procedure-related removal and device-related serious adverse events through 180 after insertion.

Treatment for Necrobiosis Lipoidica Gets Orphan Drug Designation

Treatment for Necrobiosis Lipoidica Gets Orphan Drug Designation

The FDA has granted Orphan Drug Designation to PCS499 (Processa Pharmaceuticals) for the treatment of necrobiosis lipoidica.

AMA: Federal Government Must Tackle Rising Insulin Prices

AMA: Federal Government Must Tackle Rising Insulin Prices

U.S. officials need to take action to control spiking insulin prices, the American Medical Association says.

Stressful Life Events in Childhood and Development of Type 1 Diabetes

Stressful Life Events in Childhood and Development of Type 1 Diabetes

Children of parents experiencing stressful and severe life events in early childhood may be at risk for type 1 diabetes developing.

T1D Self-Management Varies With Adult Developmental Stages

T1D Self-Management Varies With Adult Developmental Stages

Researchers examined patterns of diabetes self-management behaviors and predictors of glycemic control in 7,153 adults enrolled in the Type 1 Diabetes Exchange clinic registry.

Asymptomatic Hypoglycemia Risk With Frequent Hypoglycemia in T1D

Asymptomatic Hypoglycemia Risk With Frequent Hypoglycemia in T1D

Investigators recorded hypoglycemic symptoms and monitored blood sugar levels by continuous glucose monitoring for 6 days.

Individuals With Type 1 Diabetes See Improvement With Continuous Glucose Monitoring

Individuals With Type 1 Diabetes See Improvement With Continuous Glucose Monitoring

Investigators seek to determine he effects of continuous glucose monitoring on daytime and nocturnal hypoglycemia in patients with type 1 diabetes.

Oral T1D Treatment Zynquista to Be Reviewed by FDA

Oral T1D Treatment Zynquista to Be Reviewed by FDA

The NDA was supported by data from the Phase 3 inTandem clinical trial program which assessed the safety and efficacy of Zynquista in ~3000 adults with inadequately controlled type 1 diabetes.

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Investigators examined glycemic control variations in 8 high-income countries from multicenter registries in children with type 1 diabetes.

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

For physically active adults with type 1 diabetes, the addition of glucagon delivery to a closed-loop system using wearable sensors with automated exercise detection is associated with reduced hypoglycemia.

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

For children and adults with type 1 diabetes, consuming a very low-carbohydrate diet is associated with exceptional glycemic control.

FDA: REMS No Longer Needed for Inhaled Insulin Afrezza

FDA: REMS No Longer Needed for Inhaled Insulin Afrezza

Upon review of the proposed supplemental New Drug Application (sNDA), the FDA has determined that the communication plan is no longer needed as an element of the REMS to ensure the benefits of Afrezza outweigh its risks.

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

Brief structured education in addition to informed support in active insulin dose self-adjustment underpinned by targeted self-monitoring of blood glucose lead to sustained falls in severe hypoglycemia rates in individuals at high risk.

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

The study highlights mitochondrial and autophagic differences in the muscles of young adults with type 1 diabetes with moderate glycemic control who exceed recommended activity levels.

CDC Reports on Diabetes Prevalence by Type in the United States

CDC Reports on Diabetes Prevalence by Type in the United States

The CDC conducted a study to estimate the prevalence of diagnosed diabetes among adults in 2016 by primary type.

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

For patients with type 1 diabetes, artificial pancreas treatment is efficacious, increasing the proportion of time spent in the near normoglycemic range.

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Young Adults With Type 1 Diabetes Show Muscle Metabolic Deficiencies

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle.

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Autism Does Not Affect Metabolic Control in Type 1 Diabetes

Awareness of ASD and its manifestations and comorbidities remain imperative in the treatment of T1D, as both conditions require long-term medical follow-up to continue improving diabetes care and metabolic control outcomes.

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

The type of sciatic nerve lesions observed in patients with diabetic peripheral neuropathy was found to differ in type 1 and type 2 diabetes.

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

For adults with type 1 diabetes with suboptimal control despite using multiple insulin injections, continuous glucose monitoring seems cost-effective, with improved glucose control.

Pharmacists Can Help With Diabetes Management via Telemedicine

Pharmacists Can Help With Diabetes Management via Telemedicine

Telemedicine could provide real-time feedback loop and allow pharmacists to help patients self-manage.

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Young adults with type 1 diabetes have altered neural responses during working memory processing.

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

IPITA and EPITA held a workshop to develop consensus for a joint statement on the definition of function and failure of current and future forms of β-cell replacement therapy.

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Researchers conducted a systematic literature review to identify studies on cognitive function in children with type 1 diabetes.

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Anti-osteoporotic medications (mainly bisphosphonates) seem to equally prevent bone loss, especially in the lumbar spine, in patients with diabetes compared with patients without diabetes.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

There are significant improvements in health-related quality of life following islet transplantation in patients with type 1 diabetes complicated by severe hypoglycemia.

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