Type 1 Diabetes

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Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

Distinct Mechanisms Underlie Nerve Damage in Peripheral Neuropathy in T1D vs T2D

The type of sciatic nerve lesions observed in patients with diabetic peripheral neuropathy was found to differ in type 1 and type 2 diabetes.

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

Continuous Glucose Monitoring Cost-Effective in Type 1 Diabetes

For adults with type 1 diabetes with suboptimal control despite using multiple insulin injections, continuous glucose monitoring seems cost-effective, with improved glucose control.

Pharmacists Can Help With Diabetes Management via Telemedicine

Pharmacists Can Help With Diabetes Management via Telemedicine

Telemedicine could provide real-time feedback loop and allow pharmacists to help patients self-manage.

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Altered Neural Responses in Memory Processing With Type 1 Diabetes

Young adults with type 1 diabetes have altered neural responses during working memory processing.

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

IPITA and EPITA held a workshop to develop consensus for a joint statement on the definition of function and failure of current and future forms of β-cell replacement therapy.

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Glycemic Extremes in T1D Effect Cognitive Skills in Children

Researchers conducted a systematic literature review to identify studies on cognitive function in children with type 1 diabetes.

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Diabetes Does Not Alter Anti-Osteoporotic Treatment Response

Anti-osteoporotic medications (mainly bisphosphonates) seem to equally prevent bone loss, especially in the lumbar spine, in patients with diabetes compared with patients without diabetes.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

Islet Transplantation Improves Quality of Life in Type 1 Diabetes

There are significant improvements in health-related quality of life following islet transplantation in patients with type 1 diabetes complicated by severe hypoglycemia.

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

Accuracy of Novel Implantable Continuous Glucose Monitoring Device Assessed

Researchers assessed the safety and accuracy of an implantable continuous glucose measurement in adults diagnosed with type 1 and type 2 diabetes.

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Low-Grade Inflammatory Markers May Help Differentiate Diabetes Diagnoses in Adults

Study provided evidence of significant differences in median serum concentrations of circulating adipose-related inflammatory biomarkers across the main diabetes types.

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

Dexcom G6 Integrated Continuous Glucose Monitoring System Gets FDA Approval

The FDA reviewed data for the device through the de novo premarket review pathway, a regulatory pathway for novel, low-to-moderate-risk devices that are not substantially equivalent to an already legally marketed device.

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Toujeo Max SoloStar Gets FDA Approval for Patients With Diabetes

Sanofi announced that the Food and Drug Administration (FDA) has approved Toujeo (insulin glargine 300 Units/mL) Max SoloStar, a long-acting insulin pen that holds 900 Units of Toujeo and provides up to 160 Units/mL per injection.

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

Physiologic Response to Glucagon in Type 1 Diabetes After Alcohol Consumption

Researchers assessed whether alcohol intake affects response to glucagon in individuals with type 1 diabetes.

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

Sotagliflozin NDA Submitted to FDA for Type 1 Diabetes

The NDA is based on results from a large placebo-controlled, phase 3 trial that included 1402 patients with type 1 diabetes who were receiving insulin therapy.

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Influence of Gender on Cardiovascular Risk and Glycemic Control in T1D

Researchers assessed differences in glycemic control, major cardiovascular risk factors, diabetes-related complications, sexual dysfunction prevalence, and endothelial function in young men and women with type 1 diabetes.

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D

For pregnant women with type 1 diabetes, a closed-loop system is associated with comparable glucose control and significantly less hypoglycemia than sensor-augmented pump therapy.

MiniMed 670G System Improves Glycemic Outcomes in Children With T1D

MiniMed 670G System Improves Glycemic Outcomes in Children With T1D

Research findings indicate improved glycemic outcomes in children with T1D using the MiniMed 670G system, similar to those observed for adolescents and adults.

Minority Youths With T1D Have Poor Prognostic Factors, More Complications

Minority Youths With T1D Have Poor Prognostic Factors, More Complications

Researchers assessed racial and ethnic differences in outcomes among patients in the first 3 years following diagnosis of type 1 diabetes.

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Proliferative Diabetic Retinopathy Independently Associated With CVD in T1D

Study found that the absence of proliferative diabetic retinopathy in those with stage 3b chronic kidney disease is associated with a lower prevalence of cardiovascular disease in patients with long duration of type 1 diabetes.

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

Study suggests that single-hormone artificial pancreas systems may be sufficient for overnight control even in a high-risk group of hypoglycemia-unaware participants with documented nocturnal hypoglycemia.

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

High-quality studies are needed to determine whether tight intrapartum glycemic control is superior to more relaxed glycemic targets intrapartum for women with diabetes in pregnancy.

Parental History of T1D May Increase Risk for ADHD in Offspring

Parental History of T1D May Increase Risk for ADHD in Offspring

Researchers calculated the hazard ratio of ADHD in offspring of patients with type 1 diabetes compared with the general population.

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

Disordered Eating Affects HbA1c in Adolescents With Type 1 Diabetes

For youth with type 1 diabetes, disordered eating behaviors are associated with higher hemoglobin A1c but not with measures of glycemic variability.

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Higher rates of operative delivery and falling gestational age at delivery suggest that this is either reflected by, or despite, increasing obstetric intervention.

Genetic Variants Linked to Phenotypic Heterogeneity of Type 1 Diabetes

Genetic Variants Linked to Phenotypic Heterogeneity of Type 1 Diabetes

Transcription factor 7 like 2 genetic variants contribute to phenotypic heterogeneity of type 1 diabetes.

T1D, T2D May Have Protective Effects on Risk for Migraine

T1D, T2D May Have Protective Effects on Risk for Migraine

Results from a study investigating diabetes and migraine in the Norwegian population show that type 1 and type 2 diabetes were significantly associated with a decreased risk for migraine.

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Type 1 Diabetes Associated With Higher Rates of Serious Infection

Patients with diabetes had higher rates for all 19 infection categories with the highest incidence rate ratios seen for bone and joint infections, sepsis, and cellulitis.

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

No Difference in Hydrolyzed vs Conventional Formula Among Infants at Risk for T1D

Weaning to a hydrolyzed formula did not reduce the risk of type 1 diabetes in children with an increased disease risk.

Trends in CVD, Risk Factors, and Medications in Children With T1D

Trends in CVD, Risk Factors, and Medications in Children With T1D

Children with T1D had statistically significantly higher prevalence rates of hypertension, hypercholesterolemia, and used more CV medication compared with a matched diabetes-free reference cohort in the period after the onset of diabetes.

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