TYLENOL w. CODEINE #4 CIII
Generic Name and Formulations:
Codeine phosphate 60mg, acetaminophen 300mg; tabs; contains sulfites.
Janssen Pharmaceuticals, Inc.
Indications for TYLENOL w. CODEINE #4:
Mild to moderately severe pain.
#3: 1–2 tabs every 4 hours. #4: 1 tab every 4 hours.
Post-op pain management in children who have undergone tonsillectomy and/or adenoidectomy.
Risk of respiratory depression and death related to ultra-rapid metabolizers of codeine (esp. in children in post-op tonsillectomy and/or adenoidectomy). Hepatotoxicity (w. acetaminophen >4g/day). Obstructive sleep apnea. Head injury. Increased intracranial pressure. Acute abdomen. Impaired renal, hepatic, thyroid, or adrenocortical function. GI or GU obstruction. Addison's disease. Asthma. Drug abusers. Sulfite sensitivity. Elderly. Debilitated. Labor and delivery. Pregnancy (Cat.C). Nursing mothers.
Potentiation with alcohol, general anesthetics, tranquilizers (eg, chlordiazepoxide, sedative-hypnotics), other CNS depressants, MAOIs, tricyclic antidepressants, anticholinergics.
Opioid + analgesic.
Drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, constipation, urinary retention, rash; overdosage: respiratory depression, hepatotoxicity.
#3—100, 1000; #4—100, 500
Endocrinology Advisor Articles
- Soluble Klotho Levels Predictive of Kidney Failure in Type 2 Diabetes
- Clinicians May Be Overtreating Older Patients With Diabetes
- Comorbid and Pharmacologic Factors Increase Risk for Gastrointestinal Disorders in Diabetes
- Obesity Risk in Infants Born to Women With Diabetes
- Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers
- Diabetes May Decrease Ability to Feel Acid Regurgitation
- Autism Does Not Affect Metabolic Control in Type 1 Diabetes
- Hormonal Contraceptives May Adversely Affect Psychological Health in Adolescent Girls
- Obesity Can Negatively Effect Liver in Children as Young as 8
- Recommendations Developed on Gender Equity in Medicine