Generic Name and Formulations:
Dorzolamide HCl 2%; oph soln; contains benzalkonium chloride.
Merck & Co., Inc.
Indications for TRUSOPT:
Open-angle glaucoma. Ocular hypertension.
Adults and Children:
1 drop 3 times daily.
Hepatic impairment. Severe renal impairment (CrCl <30mL/min): not recommended. Discontinue if ocular effects (eg, conjunctivitis, lid reactions) occur. Soft contact lenses. Pregnancy (Cat.C). Nursing mothers: not recommended.
Concomitant oral carbonic anhydrase inhibitors: not recommended. May inhibit renal excretion of basic drugs and promote excretion of acidic drugs. May increase salicylate toxicity (acidosis).
Carbonic anhydrase inhibitor (sulfonamide).
Burning, stinging, bitter taste, punctate keratitis, ocular allergic reaction, blurred vision, tearing, dryness, photophobia; possible sulfa-like systemic effects.
Endocrinology Advisor Articles
- Effect of HbA1c and Perioperative Glucose on Postoperative Mortality
- GLP-1 Agonists Superior to DPP-4 Inhibitors for Reducing HbA1c, Weight in T2D
- Effect of Growth Hormone Treatment on BMD in Adults With Prader-Willi Syndrome
- Case for Continuous Glucose Monitoring in Youth-Onset Type 2 Diabetes
- Telemedicine Expands Access to Rural, Low-Income, Isolated Communities
- American College of Physicians Releases 4 Guidelines for HbA1c Targets in T2D
- Dyslipidemia Drug Indications
- No Difference in Weight Loss Outcomes With Low-Fat vs Low-Carbohydrate Diet
- Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture
- Pioglitazone May Reduce Cardiovascular, Noncardiovascular Mortality in T2D
- Once-Daily Oral Contraceptive for Men Shows Promise
- MiniMed 670G System Improves Glycemic Outcomes in Children With T1D
- Semaglutide May Be Useful for Treating Obesity in People Without Diabetes
- Low Sperm Count Linked to Poor Metabolic, Cardiovascular, Bone Health
- Estrogen Improves Eating Behavior, Psychopathology in Oligo-Amenorrheic Athletes