Thyroid

Denosumab May Increase BMD in Women With Primary Hyperparathyroidism

Denosumab May Increase BMD in Women With Primary Hyperparathyroidism

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Study assessed the effect of denosumab on bone mineral density and incident fractures in older adults with primary hyperparathyroidism who could not undergo or refused surgery.

Unexplained Infertility Linked to Higher Thyroid-Stimulating Hormone in Women

Unexplained Infertility Linked to Higher Thyroid-Stimulating Hormone in Women

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Study raises the question of whether treatment with thyroid hormone replacement for individuals with TSH levels >2.5 mIU/L may be an economical first step in treating unexplained infertility.

BMD and Parathyroid Hormone Levels in Pseudohypoparathyroidism 1B

BMD and Parathyroid Hormone Levels in Pseudohypoparathyroidism 1B

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Study showed that parathyroid hormone was a significant predictor of lumbar spine bone mineral density Z-score for pseudohypoparathyroidism 1B patients.

Antithyroid Drugs Increase Risk of Congenital Malformations

Antithyroid Drugs Increase Risk of Congenital Malformations

Exposure to anti-thyroid drugs during the first trimester of pregnancy is associated with increased risk of congenital malformations.

First trimester exposure to antithyroid drugs associated with increased risk of birth defects

First trimester exposure to anytithyroid drugs was associated with a greater risk of congenital malformations, especially for pregnant women who were given prescriptions for methimazole or both methimazole and propylthiouracil.

Thyroid hormone supplementation may be a promising treatment for idiopathic pulmonary fibrosis [PreClinical]

An enzyme involved in thyroid hormone activation was found to be elevated in patients with pulmonary fibrosis.

Evaluating Surgery Performance and Care Quality in Thyroidectomy

Evaluating Surgery Performance and Care Quality in Thyroidectomy

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Investigators aimed to determine strategies for improvement to reduce complications after thyroidectomy.

Thyroid Cancer Less Likely to Progress in Pediatrics, Young Adults

Thyroid Cancer Less Likely to Progress in Pediatrics, Young Adults

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An observational study was conducted by investigators to evaluate the progression of thyroid cancer in young individuals by ultrasonography.

Validation of Ultrasound Risk Stratification Systems for Pediatric Thyroid Nodules

Validation of Ultrasound Risk Stratification Systems for Pediatric Thyroid Nodules

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Investigators assessed the utilization of ATA risk stratification and TI-RADS ultrasound based systems for the assessment of pediatric thyroid nodules.

Imaging Studies in Hypothyroidism Evaluation Linked to Unnecessary Risks

Imaging Studies in Hypothyroidism Evaluation Linked to Unnecessary Risks

Thyroid ultrasonography, which may lead to the discovery of incidental nodules, anxiety, and high cost, is not required in evaluation for hypothyroidism.

Transoral Endoscopic Thyroidectomy Vestibular Approach: Safety and Outcomes

Transoral Endoscopic Thyroidectomy Vestibular Approach: Safety and Outcomes

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The transoral endoscopic thyroidectomy vestibular approach can be a safe procedure in select patients, with outcomes similar to those of open thyroidectomy.

Wide Variation Noted in Total, Partial Thyroidectomy Rates by US Region

Wide Variation Noted in Total, Partial Thyroidectomy Rates by US Region

A 6.2-fold variation in thyroidectomy rates was noted throughout the US.

Predicting Hypocalcemia in Children Following Thyroidectomy: Is PTH Level Useful?

Predicting Hypocalcemia in Children Following Thyroidectomy: Is PTH Level Useful?

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While parathyroid hormone levels may be used to anticipate calcium decline, a "normal" PTH level does not always correctly predict postoperative calcium level.

Safety, Efficacy of Early Thyroidectomy in Pediatric MEN2

Safety, Efficacy of Early Thyroidectomy in Pediatric MEN2

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Early thyroidectomy was preventative in a majority of pediatric patients with MEN2.

Proper Treatment in Children With Congenital Hypothyroidism Can Aid Behavior

Proper Treatment in Children With Congenital Hypothyroidism Can Aid Behavior

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Both over- and undertreatment of congenital hypothyroidism can result in negative behavioral outcomes.

Central Congenital Hypothyroidism Detection in Neonates

Central Congenital Hypothyroidism Detection in Neonates

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Screening programs that measure T4 with reflex TSH in newborns with T4 below a specified cutoff have the potential to detect central congenital hypothyroidism (CCH) and have shown a higher prevalence of CCH than previously thought.

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

AAP Shares List of 5 Unnecessary Pediatric Tests and Procedures

The American Academy of Pediatrics urges careful consideration between parents and clinicians prior to ordering these tests.

Watch and Wait: Examining Rates of Tumor Growth in Active Thyroid Surveillance

Watch and Wait: Examining Rates of Tumor Growth in Active Thyroid Surveillance

No regional or distant metastases developed during active surveillance in low-risk patients.

Does Thyroxine Tx in Hypothyroidism Cause Thyroid Cancer?

Does Thyroxine Tx in Hypothyroidism Cause Thyroid Cancer?

Irregular users of thyroxine were less likely to develop thyroid cancer compared to regular users.

Impaired Vascular Dysfunction in Primary Hyperparathyroidism May Impact Cognition

Impaired Vascular Dysfunction in Primary Hyperparathyroidism May Impact Cognition

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It has been previously reported that parathyroidectomy can reverse cognitive dysfunction associated with primary hyperparathyroidism.

Thyroid Dysfunction Not a Risk Factor for Carotid Plaque Development

Thyroid Dysfunction Not a Risk Factor for Carotid Plaque Development

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Subclinical thyroid dysfunction did not influence the cumulative incidence of new carotid plaques in healthy individuals aged 20 or older.

Radioiodine Therapy and Hemorrhagic Stoke: Are Risk Levels Increased?

Radioiodine Therapy and Hemorrhagic Stoke: Are Risk Levels Increased?

Stroke risk with I-131 therapy for thyroid cancer was examined via 2 cohorts using 1:1 propensity score matching.

Maternal Thyroid-Stimulating Hormone, Free Thyroxine Associated With BMI

Maternal Thyroid-Stimulating Hormone, Free Thyroxine Associated With BMI

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Maternal thyroid function and weight gain in early pregnancy were associated with hypothyroidism, but not hyperthyroidism.

Manic Relapse in Bipolar Disorder Linked to Thyroid Disease

Manic Relapse in Bipolar Disorder Linked to Thyroid Disease

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Relapse risk was highest among patients with hypothyroidism.

Parathyroidectomy for Secondary, Tertiary Hyperparathyroidism Increases Morbidity and Mortality

Parathyroidectomy for Secondary, Tertiary Hyperparathyroidism Increases Morbidity and Mortality

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After parathyroidectomy, morbidity and mortality rates were considerably higher in patients with secondary and tertiary vs primary hyperparathyroidism.

Sleep Disordered Breathing Impacted by Hypothyroidism, Obesity

Sleep Disordered Breathing Impacted by Hypothyroidism, Obesity

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Adult patients with obesity and hypothyroidism have lower-than-average sleep oxygen saturation.

Active Ophthalmopathy Benefits From Teprotumumab Treatment

Active Ophthalmopathy Benefits From Teprotumumab Treatment

Patients given teprotumumab were more likely to experience a response at 24 weeks vs placebo.

Efficacy of Daily vs Weekly Levothyroxine for Hypothyroidism

Efficacy of Daily vs Weekly Levothyroxine for Hypothyroidism

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Researchers examined the safety and efficacy of daily vs weekly levothyroxine therapy for hypothyroidism in young and middle aged adults.

TSH Lab Results With Brand vs Generic Levothyroxine

TSH Lab Results With Brand vs Generic Levothyroxine

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Synthroid was associated with an 11% lower likelihood of having out-of-range TSH lab values vs generic levothyroxine.

USPSTF: No Thyroid Cancer Screening in Asymptomatic Adults

USPSTF: No Thyroid Cancer Screening in Asymptomatic Adults

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Thyroid cancer screening in asymptomatic adults was given a D recommendation because of the negative effects of screening outweighing any benefits.

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