USPSTF Issues Recommendation for Vitamin D, Calcium Supplementation for Fracture Prevention
The USPSTF has released recommendations for vitamin D and calcium supplementation for the primary prevention of fractures in community-dwelling adults.
Osteoporosis
Greater Bone Formation With Teriparatide vs Zoledronic Acid in Osteoporosis
Researchers have determined that treatment for osteoporosis with teriparatide is associated with greater bone formation than treatment with zoledronic acid.
Low Sperm Count Linked to Poor Metabolic, Cardiovascular, Bone Health
Researchers tested whether semen quality and reproductive function could be a marker of general health in men.
Gastric Bypass Surgery Linked to Increased Risk for Nonvertebral Fractures
Roux-en Y gastric bypass increased the likelihood of nonvertebral fractures, including hip, wrist, and pelvic fractures.
Effect of Growth Hormone Treatment on BMD in Adults With Prader-Willi Syndrome
Researchers investigated the effects of growth hormone vs placebo, as well as the effects of sex steroid replacement therapy on bone mineral density in growth hormone-treated young adults with Prader-Willi syndrome who had attained adult height.
Osteoporotic Fracture Risk Predicted by Vertebral Trabecular Attenuation on Routine CT
Researchers showed that decreased L1 trabecular attenuation is associated with increased risk for future osteoporotic fractures in adult patients aged ≥65 years undergoing abdominopelvic CT scans for other indications.
Romosozumab Followed by Alendronate Decreases Fracture Risk in Women With Osteoporosis
In postmenopausal women at high risk for fracture, treatment with romosozumab for 12 months, followed by alendronate, was associated with significantly fewer hip fractures than treatment with alendronate alone.
Fracture Risk in Postmenopausal Women With Osteoporosis May Improve With Growth Hormone Therapy
A recent literature review and meta-analysis indicates that growth hormone therapy may reduce the risk for fracture in patients with osteoporosis.
Teriparatide More Effective Than Risedronate in Osteoporotic Fractures
Teriparatide is associated with a lower risk for new vertebral and clinical fractures compared with risedronate in post-menopausal women being treated for severe osteoporosis.
Risks Associated With Denosumab Discontinuation
Risk of vertebral fractures may be increased with discontinuation of denosumab therapy.
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