Tesomet Receives Orphan Drug Status for Hypothalamic Obesity
Tesomet is an investigational fixed-dose combination therapy of tesofensine, a triple monoamine reuptake inhibitor, and metoprolol, a beta-1 selective blocker.
Metabolic Disorders
In Pediatric Type 1 Diabetes, Continuous SQ Insulin Infusions Do Not Lower HbA1c More Than MDI
Study authors conducted a retrospective cohort study to compare CSII and MDI treatments on metabolic control, body mass index, and prevalence of severe hypoglycemia in children.
Plasma Selenium Predictive of Thyroid Dysfunction in Postpartum Women
Researchers investigated thyroid function in women 6 months postpartum relative to maternal iodine, selenium, and iron status.
NAFLD in Lean Patients May Be Linked to Metabolic Syndrome, Cardiovascular Risk
Investigators aimed to determine the metabolic and cardiovascular phenotypes of lean patients with NAFLD.
FDA: More Data Needed to Support Arimoclomol in Niemann-Pick Disease Type C
Arimoclomol is an investigational oral drug candidate that is designed to amplify and sustain the cellular production of heat shock proteins.
Obesity Treatments
A comparative list of medications by pharmacological class for the treatment of obesity.
Digital Therapeutics Platform Effective for Weight Loss, BMI Reduction
The use of a digital therapeutics platform in people with obesity and metabolic syndrome can lead to a reduction in both weight and body mass index (BMI), thereby reducing risk for comorbidities, according to study results presented at the 30th Annual Scientific and Clinical Congress of the American Association of Clinical Endocrinologists (ENVISION 2021). Digital…
Repeated Fecal Microbiota Transplantations in Patients With Obesity and Diabetes
Researchers studied whether combining FMT with lifestyle modifications could enhance the engraftment of favorable microbiota in patients with obesity and T2DM.
Pediatric Cancer Survivors and Diabetes: What Are the Risks?
Diabetes and metabolic syndrome represent two of the most common long-term complications in survivors of childhood cancer.
Low-Fat Dairy Consumption Linked to Decreased Risk of Incident Metabolic Syndrome in Children, Adolescents
A team of investigators assessed the impact of the consumption of dairy products on the incidence of metabolic syndrome among children and adolescents.
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