Serum Estradiol Levels Predictive of Fractures During Menopausal Transition
Measuring serum estradiol during the menopausal transition might help identify women at higher risk for fractures.
Menopause
Osphena Approved for Moderate to Severe Vaginal Dryness Due to Menopause
The expanded approval was based on safety and efficacy data from a confirmatory Phase 3 randomized, double-blind, placebo-controlled multicenter study evaluating Osphena in patients with moderate to severe vaginal dryness.
Mindfulness, Stress Linked to Menopausal Symptoms
Higher mindfulness and lower stress are independently associated with lower menopausal symptom scores among midlife women.
Impact of Women’s Health Initiative on Menopausal Hormone Therapy Trends
Initiation and continuation trends in menopausal hormone therapy may have been influenced by the premature cessation of the 2002 Women’s Health Initiative trial, which was halted due to safety concerns.
Topical Methyl Estradiolpropanoate Safe, Effective for Treating Estrogen-Deficient Skin
A study was conducted to assess the safety, tolerability, and efficacy of methyl estradiolpropanoate, a topical soft estrogen cosmeceutical for the treatment of estrogen-deficient skin.
Higher Risk for Venous Thromboembolism With Oral vs Transdermal HRT
Oral preparations of hormone replacement therapy for the treatment of menopausal symptoms are associated with a greater risk for VTE compared with transdermal formulations.
Vaginal Estrogen Use Not Associated With Elevated Chronic Disease Risk
Vaginal estrogen use or nonuse did not carry different risks for cardiovascular outcomes, cancer outcomes, or hip fracture.
Edentulism Associated With Risk for Hypertension After Menopause
Postmenopausal women with edentulism are at an increased risk for developing hypertension.
Menopause Symptoms Associated With Intimate Partner Violence, Sexual Assault
Intimate partner violence, sexual assault, and symptoms of posttraumatic stress disorder may be associated with menopause symptoms.
Prenatal Exposure to Famine Increases Risk for Early Menopause
Fetal exposure to famine is associated with an increased risk for early menopause.
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