Osilodrostat Effective for Patients With Cushing Disease
Investigators report outcomes from the LINC-4 study that evaluated outcomes following osilodrostat treatment for Cushing disease.
Hypercortisolism
Hair Cortisol Measurement Not Effective for Identifying Autonomous Cortisol Secretion in Adrenal Incidentalomas
A team of investigators measured concentrations of 5 corticosteroid hormones in the keratin matrix of patients with adrenal incidentalomas with or without cortisol autonomy.
Radiologic Phenotyping of Adrenal Adenomas May Identify Autonomous Cortisol Secretion
A team of investigators assessed the ability of computed tomographic-derived, 3-dimensional volumetry to predict autonomous cortisol secretion among patients with adrenal adenomas.
Cushing Syndrome May Be Predicted More Accurately With New Diagnostic Test
The complexity of Cushing syndrome often makes diagnosis difficult. Researchers sought to create a diagnostic tool that could determine which patients may be at risk for developing the disease.
Cortisol Level and Dexamethasone Suppression Test Improve Disease Analysis
Adrenal masses and people who may have Cushing syndrome are often evaluated with a dexamethasone suppression test (DST), but false positives occur. Researchers examined whether free cortisol assessment during DST would aid in diagnosis.
Depression, Anxiety Associated with Osteocalcin, Cortisol in Hyperparathyroidism
Anxiety and depression in people with hyperparathyroidism may be related to levels of 2 key hormones in the body, according to researchers.
Measuring Bone Characteristics and Derangement in Patients With Adrenal Incidentaloma
High-resolution peripheral quantitative computed tomography can be used to assess bone abnormalities in patients with adrenal incidentaloma.
Mifepristone an Effective Alternative to Surgery for Patients With Bilateral Macronodular Adrenal Hyperplasia
Mifepristone may be an effective alternative to adrenalectomy in patients with hypercortisolism caused by primary bilateral macronodular adrenal hyperplasia.
Hypertension Associated With Glucocorticoid Sensitivity and Activity in Women Without Hypercortisolism
Hypertension may be associated with degree of glucocorticoid suppression and peripheral activation in postmenopausal women.
High Prevalence of Diabetes in Patients With Primary Aldosteronism
Prevalence of diabetes is higher in patients with primary aldosteronism and was found to be related to suspected subclinical hypercortisolism.
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