Short-Acting Testosterone Replacement Therapy Better for Spermatogenesis
Study authors hypothesized that longer-acting testosterone replacement therapy will have significant impact on suppressing HPG axis compared with short-acting TRT preparations.
Hormone Replacement Therapy
Growth Hormone in Children Born Small for Gestational Age May Be Effective Regardless of Age of Treatment
Study authors assessed the long-term effectiveness and safety of GH in real-life clinical practice and whether age mattered at the time of treatment initiation.
Levothyroxine Deprescribing Framework Needed for Thyroid Replacement Hormone Tapering
Researchers set out to summarize clinical outcomes experienced by patients who discontinue thyroid hormone replacement therapy.
Long-Acting Therapy for Growth Hormone Deficiency Receives Orphan Designation
The FDA has granted Orphan Drug designation to TransCon hGH (lonapegsomatropin; Ascendis Pharma), a long-acting prodrug of somatropin, for the treatment for growth hormone deficiency.
Menopausal Age, Type Not Related to Cardiovascular Risk Factors Later in Life
The age at and cause of period cessation were not found to be associated with conventional cardiovascular risk factors across middle age and later life.
First Testosterone Undecanoate Softgel Approved by FDA for Hypogonadism
Jatenzo® (testosterone undecanoate; Clarus Therapeutics), an oral testosterone replacement therapy, is now available for the treatment of hypogonadism.
ACP Issues Guidelines for Use of Testosterone Therapy in Age-Related Low Testosterone
The American College of Physicians has issued a set of recommendations to clarify the potential benefits and harms of testosterone therapy in men with age-related low testosterone.
Breast Cancer Rates Differ With Use of Estrogen Alone vs Estrogen Plus Progestin
For postmenopausal women, conjugated equine estrogen alone is associated with a long-term decrease in breast cancer incidence, while CEE plus medroxyprogesterone acetate is associated with increased incidence.
Waist Circumference Affects Coronary Plaque Accumulation in Testosterone Therapy
Older men receiving testosterone treatment with higher waist-to-hip ratio experience greater increases in noncalcified coronary plaque volume.
Testosterone Replacement May Improve Body Composition in Male Cancer Survivors
Testosterone replacement therapy may improve body composition in young male cancer survivors with borderline-low testosterone levels.
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