Type and Timing of Menopausal Hormone Therapy May Affect Breast Cancer Risk
Use of menopausal hormonal therapy for 5 years around the start of menopause may be associated with increased risk for breast cancer.
Hormone Replacement Therapy
Bone Loss Likely After Prophylactic Bilateral Salpingo-Oophorectomy
Premenopausal women who undergo prophylactic bilateral salpingo-oophorectomy are especially prone to postoperative bone loss, which may be mitigated by hormone replacement therapy.
Estrogen Preparations Have Varying Effects on Heart Fat Accumulation in Early Menopausal Women
Exogenous estrogen preparations may have different effects on heart fat accumulation and development of coronary artery calcification in early menopausal women.
Testosterone Replacement Therapy May Increase Cardiovascular Risk
For aging men with low testosterone levels, testosterone replacement therapy may increase the risk of cardiovascular events, especially in the first two years of use.
Increase in HDL-C, Adiponectin Levels With Glucocorticoid Replacement Therapy
Glucocorticoid replacement therapy is associated with an increase in serum levels of adiponectin and high-density lipoprotein cholesterol.
Testosterone Replacement in Congenital Hypogonadotropic Hypogonadism Has Limited Effects on Bone Health
Testosterone replacement therapy prevents further bone loss at the lumbar and femoral levels in patients with congenital hypogonadotropic hypogonadism, but it does not reliably elevate bone mineral density out of the osteopenic/osteoporotic range.
Hormone Replacement Therapy May Increase Risk for Alzheimer Disease
Long-term use of systemic hormone replacement therapy may slightly increase the risk of developing Alzheimer disease.
Type of Estrogen Therapy Used Has an Impact on Adult Outcomes in Turner Syndrome
An earlier age of onset of puberty may be beneficial for adult bone density in Turner syndrome and type of hormone therapy may have a varying impact on adult health.
Impact of Women’s Health Initiative on Menopausal Hormone Therapy Trends
Initiation and continuation trends in menopausal hormone therapy may have been influenced by the premature cessation of the 2002 Women’s Health Initiative trial, which was halted due to safety concerns.
Hormone Therapy Linked to Reduced Symptomatic Knee OA in Postmenopausal Women
Hormone therapy in postmenopausal women may be protective against knee OA.
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