Effects of Estrogen-Only Treatment in Women With Prior Hysterectomy
For women aged 50 to 59 years with a history of bilateral oophorectomy, estrogen therapy may have beneficial effects in the long-term.
Hormone Replacement Therapy
Effect of Hormone Therapy on Muscle Mass in Postmenopausal Women
Although use of hormone therapy can have some protective effect on muscle mass in postmenopausal women, the benefit is small in the general population.
Type and Timing of Menopausal Hormone Therapy May Affect Breast Cancer Risk
Use of menopausal hormonal therapy for 5 years around the start of menopause may be associated with increased risk for breast cancer.
Bone Loss Likely After Prophylactic Bilateral Salpingo-Oophorectomy
Premenopausal women who undergo prophylactic bilateral salpingo-oophorectomy are especially prone to postoperative bone loss, which may be mitigated by hormone replacement therapy.
Estrogen Preparations Have Varying Effects on Heart Fat Accumulation in Early Menopausal Women
Exogenous estrogen preparations may have different effects on heart fat accumulation and development of coronary artery calcification in early menopausal women.
Testosterone Replacement Therapy May Increase Cardiovascular Risk
For aging men with low testosterone levels, testosterone replacement therapy may increase the risk of cardiovascular events, especially in the first two years of use.
Increase in HDL-C, Adiponectin Levels With Glucocorticoid Replacement Therapy
Glucocorticoid replacement therapy is associated with an increase in serum levels of adiponectin and high-density lipoprotein cholesterol.
Testosterone Replacement in Congenital Hypogonadotropic Hypogonadism Has Limited Effects on Bone Health
Testosterone replacement therapy prevents further bone loss at the lumbar and femoral levels in patients with congenital hypogonadotropic hypogonadism, but it does not reliably elevate bone mineral density out of the osteopenic/osteoporotic range.
Hormone Replacement Therapy May Increase Risk for Alzheimer Disease
Long-term use of systemic hormone replacement therapy may slightly increase the risk of developing Alzheimer disease.
Type of Estrogen Therapy Used Has an Impact on Adult Outcomes in Turner Syndrome
An earlier age of onset of puberty may be beneficial for adult bone density in Turner syndrome and type of hormone therapy may have a varying impact on adult health.
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