Mild Traumatic Brain Injury May Be Associated With Growth Hormone, Pituitary Deficiencies
Researchers discussed challenges and preventive strategies for clinicians to detect and manage patients with mild TBI-induced growth hormone deficiency.
Growth Hormone Deficiency
Study Finds Infants Born Small for Gestational Age Achieve Adequate Catch-Up Growth Without Growth Hormone Therapy
A team of investigators sought to determine the incidence of infants born small for gestational age and assess the timing of their catch-up growth.
Growth Hormone in Children Born Small for Gestational Age May Be Effective Regardless of Age of Treatment
Study authors assessed the long-term effectiveness and safety of GH in real-life clinical practice and whether age mattered at the time of treatment initiation.
Medication Misuse: Growth Hormone for Athletic Performance and Anti-Aging
There has been a significant surge in the use of growth hormone to improve athletic ability and combat aging despite no clear supporting evidence.
Diagnosis and Management of Pituitary Incidentaloma
Patient evaluation, follow-up testing, and treatment differ based on lesion size and presence of hormone abnormalities with pituitary incidentalomas.
How Does the Switch From Daily to Weekly Dosing Affect Growth Hormone Therapy Outcomes?
Switching from daily human growth hormone to once-weekly TransCon growth hormone treatment resulted in similar safety and efficacy outcomes in pediatric patients.
Long-Acting Therapy for Growth Hormone Deficiency Receives Orphan Designation
The FDA has granted Orphan Drug designation to TransCon hGH (lonapegsomatropin; Ascendis Pharma), a long-acting prodrug of somatropin, for the treatment for growth hormone deficiency.
Once-Weekly Treatment for Adult GH Deficiency Effective in Phase 3 Trial
A once-weekly growth hormone replacement therapy demonstrated superiority over placebo for patients with adult growth hormone deficiency.
Irisin Levels May Be Metabolic Biomarker for GH Replacement Therapy
Growth hormone replacement can raise irisin levels in children with growth hormone deficiency.
Normal Height Velocity Maintained With Reduced Growth Hormone Dose
Normal height velocity can be maintained in prepubertal children during the catch-up growth period by reducing growth hormone dosage by 50%.
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