Tool Developed to Assess Long-Term CVD Risk, Benefit of Lipid-Lowering Intervention
The blood levels of non-high density lipoprotein cholesterol were found to have a strong association with the long-term risk for a cardiovascular disease event.
Dyslipidemia
Trial Evaluating Fish Oil-Derived Drug for MACE Risk Reduction Discontinued
AstraZeneca is discontinuing a phase 3 trial evaluating Epanova (omega-3 carboxylic acids) in patients with mixed dyslipidemia who are at high risk of cardiovascular disease (CVD), as findings from the study showed the treatment was unlikely to be beneficial.
Lower Target for LDL-C Levels Reduces Risk for Cardiovascular Events After Stroke
High-intensity statin treatment after ischemic stroke or transient ischemic attack is associated with a reduced risk for subsequent cardiovascular events.
Benefits of Bariatric Surgery for T2D, Dyslipidemia Evident 5 Years Later
Bariatric surgery is associated with weight loss and remission of type 2 diabetes and dyslipidemia at five years postsurgery.
High Lipoprotein(a) Is a Risk Factor for CVD in Type 1 Diabetes
For patients with type 1 diabetes, lipoprotein(a) [Lp(a)] is a significant risk factor for macrovascular disease, albuminuria, and calcified aortic valve disease.
APO(a)-LRX Found to Reduce Lipoprotein(a) Levels
For patients with elevated lipoprotein(a) levels and established cardiovascular disease, hepatocyte-directed antisense oligonucleotide AKCEA-APO(a)-LRX (APO(a)-LRX) reduces lipoprotein(a) levels.
HDL Cholesterol Can Be Used to Monitor Triglycerides, Remnant Cholesterol
Low HDL-C may be used to monitor long-term average triglycerides and remnant cholesterol levels, similar to how high hemoglobin A1c is used to monitor long-term elevated glucose levels.
Icosapent Ethyl Approved to Reduce Risk for CV Events in High-Risk Patients
Increased risk of atrial fibrillation and bleeding with Vascepa observed in cardiovascular outcomes trial.
AHA Recommends a Focus on Healthy Dietary Choices Over Cholesterol Cutoffs
Guidance focused on dietary patterns may be better to improve healthy eating and promote cardiovascular health, according to the American Heart Association.
Non-HDL Cholesterol Levels Linked to Long-Term ASCVD Risk
Fifty percent reduction in non-HDLC concentration linked to reduced risk for CVD event by age 75 years
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