Evinacumab Lowers LDL Cholesterol in Refractory Hypercholesterolemia
In this phase 2 trial, patients with hypercholesterolemia and clinical atherosclerotic cardiovascular disease were recruited from 85 sites across 20 countries.
Dyslipidemia
Inclisiran Approval Held Up by Inspection-Related Issues
Inclisiran is a chemically synthesized small interfering RNA that targets proprotein convertase subtilisin-kexin type 9 (PCSK9) messenger RNA.
Remnant Cholesterol Concentration an Independent Predictor of Poor CV Outcomes
Poor cardiovascular outcomes are more likely in patients with elevated remnant cholesterol or triglycerides.
Statin Use for Primary Prevention of CVD Lower for Sexual Minorities
The lesbian, gay, and bisexual (LGB) population has a lower prevalence of statin use for primary prevention of cardiovascular disease.
LDL-C Polygenic Risk Score and ASCVD in Monogenic Familial Hypercholesterolemia
Elevated LDL-C polygenic scores associated with higher LDL-C levels and increased risk for ASCVD in patients with monogenic familial hypercholesterolemia.
Elevated LDL-C Linked to Higher Risk for ASCVD in People Aged 70 to 100 Years
Elevated LDL-C levels in people ages 70 to 100 years were found to be associated with a higher absolute risk for myocardial infarction and atherosclerotic cardiovascular disease.
Mediterranean Diet May Reduce Type 2 Diabetes in Women
Higher adherence to a Mediterranean diet is associated with a 30 percent risk reduction in type 2 diabetes in women.
Should Older Adults With High LDL Receive Statin Therapy?
Older adults have an increased risk for myocardial infarction and ASCVD in association with elevated levels of LDL cholesterol; and LDL-lowering therapies are effective for reducing cardiovascular events in older adults.
Endocrine Society Issues Practice Guideline for Lipid Management in Endocrine Disorders
A clinical practice guideline was released by the Endocrine Society providing guidance for the treatment of dyslipidemia in those with endocrine diseases.
The Lipid Paradox and CVD Risk in Rheumatoid Arthritis
Mechanistic and outcomes studies are warranted to elucidate the lipid paradox and CVD risk in rheumatoid arthritis (RA).
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