Subclinical Cardiac Pathology Common in Women With HIV
In women with ART-treated HIV, there is a 3-fold increase in intramyocardial triglyceride content and reduced diastolic function, leading to higher CVD risk.
Cardiovascular and Metabolic Disorders
Bempedoic Acid Plus Ezetimibe Lowers LDL-C When Added to Maximally Tolerated Statin Therapy
Fixed-dose bempedoic acid with ezetimibe lowered LDL-C vs placebo when added to maximally tolerated statin therapy in patients with high CVD risk and hypercholesterolemia.
Do Serum Sex Hormone-Binding Globulin, Testosterone Levels Affect CVD Risk in Men?
Men with elevated serum sex hormone-binding globulin or lower total testosterone levels might be at greater risk for cardiovascular disease.
Statin Discontinuation Linked to CV Admissions in Elderly Patients
For elderly patients taking statins for primary prevention, statin discontinuation is associated with an increased risk for admission for any cardiovascular event.
Evinacumab Effective in Homozygous Familial Hypercholesterolemia Trial
Results from a phase 3 trial evaluating the efficacy of evinacumab (Regeneron) in the treatment of patients with homozygous familial hypercholesterolemia (HoFH) showed that the investigational angiopoietin-like 3 (ANGPTL3) antibody reduced low-density lipoprotein (LDL) cholesterol by 49%.
Estrogen Preparations Have Varying Effects on Heart Fat Accumulation in Early Menopausal Women
Exogenous estrogen preparations may have different effects on heart fat accumulation and development of coronary artery calcification in early menopausal women.
Variability of BMI, HDL-C in Childhood May Predict Risk for Diabetes in Adulthood
Increased variations of body mass index and high-density lipoprotein cholesterol during childhood are independent risk factors for the development of diabetes.
High-Intensity Lipid Lowering May Benefit Very Elderly Patients After ACS
Benefit of simvastatin-ezetimibe combo after acute coronary syndrome greatest for patients ≥75 years
Dyslipidemia Treatment in the Elderly: A Pharmacologic Overview
Investigators evaluated various drug therapies for dyslipidemia in elderly patients.
Mediterranean Diet in Pregnancy May Reduce Risk for Gestational Weight Gain, Diabetes
Women consuming a Mediterranean-style diet during pregnancy gained less weight and had lower risk for gestational diabetes compared with usual care.
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