Zoledronic acid, an annual intravenous therapy for osteoporosis, sometimes causes acute-phase reactions such as fever, myalgia, and flu-like symptoms after infusion. Researchers wondered if these initial transient reactions could be used as a predictor of the drug’s efficacy in people at risk for fractures.
Researchers assessed changes in bone turnover and bone mineral density in patients with rheumatoid arthritis receiving treatment with glucocorticoids after discontinuing denosumab for 12 months.
Researchers assessed and compared the clinical efficacy of romosozumab in patients with rheumatoid arthritis osteoporosis and primary osteoporosis.
Many observational studies in medical literature support the overall benefits of vitamin D supplementation. However, whether this is actually true is the subject of a renewed debate, particularly in muscle health.
Alendronate (Alen), a bisphosphonate used to treat and prevent osteoporosis, was coupled with nanodiamonds (NDs) as part of an experiment to discover if the combination could be used as a potential osteoporosis therapy and provide greater bone-targeted drug delivery than oral osteoporosis medications.
In a poster presented at ASBMR 2021, researchers compared fracture rates and treatment adherence in women with osteoporosis who received risedronate gastro-resistant vs oral immediate-release bisphosphonates.
In a plenary poster presentation at ASBMR 2021, researchers determined whether muscle strength and performance measures improved fracture risk prediction in men.
Investigators studied the bones of adults who had thyroid cancer as children to find out if treatment for the disease carried consequences into adulthood.
Researchers identified trajectories of depression and comorbidity in patients with knee osteoarthritis, and described the characteristics of distinctive trajectories.
Primary or age-related sarcopenia is recognized as an independent disease, and advanced glycation end products (AGEs) have been associated in the pathogenesis of primary sarcopenia and other diseases related to aging. Researchers are looking for novel, less invasive ways to predict its severity and course.
