Most Osteoporosis Guidelines Do Not Discuss Patient Beliefs, Preferences
Less than 40 percent of osteoporosis clinical practice guidelines include any mention of patients’ beliefs, values, or preferences.
Bone Health
Treatments for Preventing Fracture in Postmenopausal Women Compared
Overall, treatments that were associated with the greatest relative risk reduction in fragility fractures included teriparatide, abaloparatide, denosumab, romosozumab and most bisphosphonate.
Greater Improvements in Genetic Rickets With Burosumab vs Conventional Therapy
Burosumab was found to be superior to conventional therapy of oral phosphate and active vitamin D in children with X-linked hypophosphatemia.
Bypass Surgery Reduces Micronutrients Related to Bone Metabolism in Obese Patients
Roux-en-Y gastric bypass worsens the inadequacy of micronutrients related to bone metabolism and is associated with secondary hyperparathyroidism and low bone mineral density values, particularly in adolescent patients.
Elderly Men Undertreated for Osteoporosis
Elderly men are significantly undertreated for osteoporosis.
Prior Bisphosphonate Treatment Does Not Prevent Fractures After Denosumab Discontinuation
The discontinuation of denosumab is associated with increased bone turnover markers and bone loss, but prior treatment with bisphosphonates did not seem to prevent the development of these complications.
Biomechanical CT More Cost-Effective Than DXA for Osteoporosis Screening
A biomechanical computed tomography program used to screen for osteoporosis appears to be a cost-effective alternative to standard care for adults age ≥65 years.
Zoledronate, Teriparatide Do Not Negatively Affect Carotid Intima-Media Thickness
Treatment with zoledronate or teriparatide for a year did not affect intima-media thickness of the carotid arteries in postmenopausal women with osteoporosis.
Insulin Resistance Does Not Increase Fracture Risk in Patients Without Diabetes
There is no association between insulin resistance and fracture risk in older adults without diabetes.
Bone Health in Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa
Adolescents with atypical anorexia nervosa have higher bone mass density on average than adolescents with anorexia nervosa, but still experience significant deficits in fat mass index.
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