Endocrine Therapy for Hormone Receptor-Positive Breast Cancer in Men
Results of the phase 2 MALE clinical trial comparing 3 treatment regimens in men with hormone-receptor positive breast cancer are reported.
Androgen and Reproductive Disorders
Hormone Replacement Therapy in Menopause Linked to Asthma Development
Airway symptoms may develop in menopausal women with no prior history of asthma following the initiation of hormone replacement therapy.
Platelet Rich Plasma With Gonadotropins Restores Ovarian Function in Early Menopause
This study was designed to investigate whether administering whole dimension platelet-rich plasma with gonadotropin can restore ovarian function in women who are in early menopause.
Women Who Undergo Surgery to Remove Fallopian Tubes and Ovaries Can Experience Declines in Cognitive Function
Risk-reducing bilateral salpingo-oophorectomy can reduce the risk of ovarian cancer for BRCA1 and BRCA2 carriers, but the surgery leads to early menopause. Little is known how undergoing the surgery will affect cognition in women who undergo the procedure. In this featured study, researchers share new findings.
Endocrine Disrupting Chemicals May Influence Hormonal Shifts During Pregnancy and Contribute to Postpartum Depression
Pregnancy, childbirth, and postpartum are periods of dramatic hormonal and physiologic changes that heighten susceptibility to environmental chemicals, including endocrine disrupting chemicals. This study examines whether endocrine disrupting chemicals can influence hormonal shifts during pregnancy as well as contribute to postpartum depression.
Thyroid Imbalance May be Associated With Failed Pregnancies
Thyrotropin regulates the production of thyroid hormones and their levels during gestation can have a significant effect on pregnancy outcomes. In this featured study from JAMA Network Open, researchers show how low and high maternal thyrotropin levels can increase the risk for adverse pregnancy outcomes.
Pilot Clinical Trial Shows Benefits of Hormone Therapy for Nocturia in Postmenopausal Women
Excessive urination at night, or nocturia, is not uncommon in postmenopausal women. There are a number of treatment options available but with varying degrees of success.
Challenges to Standard Prescribing Guidance for Gender-Affirming Hormone Therapy Require Future Research Endeavors
In this clinical practice review correspondence recently published in the Journal of Clinical Endocrine and Metabolism, physicians challenge some of the standard prescribing guidance for gender affirming hormone therapy.
Hormone Therapy May Reduce Nocturia After Menopause
The percentage of postmenopausal women experiencing nocturia two or more times per night was lower among those who selected systemic hormone treatment compared with no treatment.
High Hematocrit Levels Among Trans Men Associated With Testosterone Therapy
Erythrocytosis is a side effect of testosterone therapy that can increase the risk of blood clots. In this featured study, Dutch researchers conducted a 20-year follow-up in adult trans men receiving testosterone therapy finding dangerously high hematocrit levels in some patients.
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