High Prevalence of Diabetes in Patients With Primary Aldosteronism
Prevalence of diabetes is higher in patients with primary aldosteronism and was found to be related to suspected subclinical hypercortisolism.
Adrenal
Gestational Age, Birth Weight Cutoff Values May Improve Diagnosis of Congenital Adrenal Hyperplasia
Adjusting threshold levels of 17-OHP to reflect gestational age and birth weight might be a safe and efficient strategy to improve screening for CAH in newborns.
New Data for Potential Cushing Syndrome Treatment Levoketoconazole Announced
Researchers reported that mean urinary-free cortisol (mUFC) normalization with Recorlev was similar in patients with and without diabetes.
Endocrine Society Updates Congenital Adrenal Hyperplasia Clinical Practice Guidelines
The guideline highlights shared decision making among patients, their families, and physicians for the management of congenital adrenal hyperplasia.
Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk
Higher levels of aldosterone are associated with insulin resistance and incident type 2 diabetes among multiethnic individuals.
Nonfunctioning Adrenal Incidentaloma Associated With Metabolic Syndrome
Investigators sought to determine the frequency of metabolic syndrome in patients with nonfunctioning adrenal incidentalomas.
Positive Results for Recorlev in Phase 3 Cushing Syndrome Trial
Results from this single-arm, open-label study found that 30% of patients achieved normalization of mean urinary free cortisol (UFC) after 6 months of maintenance treatment with levoketoconazole, without a dose increase (P<.25).
Azedra Approved to Treat Rare Tumors of the Adrenal Gland
Azedra should be used by or under the control of physicians who are qualified by specific training and experience in the safe use and handling of radiopharmaceuticals.
Glucocorticoid Replacement Improves Circadian Rhythm in Adrenal Insufficiency
Administering glucocorticoid leads to entrainment of molecular clocks in human peripheral blood mononuclear cells by regulating BMAL-1 and PER2-3.
Age-Related Differences in Manifestation of Cushing Disease Identified
Researchers assessed disease presentation and clinical outcomes in an older population of individuals with Cushing disease.
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