Optimal Hydrocortisone Delivery Mode in Adrenal Crisis During Major Stress
The most clinically appropriate mode of hydrocortisone administration during major stress in patients with adrenal insufficiency is continuous intravenous hydrocortisone.
Adrenal
Novel Therapy for Cushing Disease Receives FDA Approval
The Food and Drug Administration (FDA) has approved Isturisa® (osilodrostat; Recordati) for the treatment of adults with Cushing disease for whom pituitary surgery is not an option or has not been curative.
Screening for Adrenal Insufficiency in Children With Eosinophilic Esophagitis
Gastroenterologists who are members of an EoE consortia are much more likely to routinely screen for adrenal insufficiency in children with eosinophilic esophagitis who are being treated with topical corticosteroids.
No Clear Distinguishing Factors for Primary Aldosteronism Plus Subclinical Cushing Syndrome
No reference criteria can definitively distinguish patients with primary aldosteronism and subclinical Cushing syndrome from those with these conditions alone.
Pheochromocytoma, Paraganglioma May Contribute to Secondary Osteoporosis
Pheochromocytomas and paragangliomas may be an important cause of secondary osteoporosis.
Management of Cushing Disease After Transsphenoidal Surgery
The clinical approach to management of Cushing disease is often complex and education on a clear approach is paramount.
Link Between Inhaled Corticosteroids in Pediatric Asthma and Hypocortisolism
A significantly lower hair cortisol concentration was observed in patients with asthma compared with healthy controls, suggesting that this measurement may be used to detect individuals at risk for hypocortisolism.
Levoketoconazole Effectively Treats Endogenous Cushing Syndrome in Phase 3 Trial
According to results of the phase 3 SONICS trial, levoketoconazole is a safe and effective treatment option for patients with Cushing syndrome.
Sex Affects Clinical Presentation of ACTH-Dependent Cushing Syndrome
Researchers examined sex differences in clinical presentation and patient outcomes in ACTH-dependent Cushing syndrome.
Increase in HDL-C, Adiponectin Levels With Glucocorticoid Replacement Therapy
Glucocorticoid replacement therapy is associated with an increase in serum levels of adiponectin and high-density lipoprotein cholesterol.
