Adjusting threshold levels of 17-OHP to reflect gestational age and birth weight might be a safe and efficient strategy to improve screening for CAH in newborns.
Researchers reported that mean urinary-free cortisol (mUFC) normalization with Recorlev was similar in patients with and without diabetes.
The guideline highlights shared decision making among patients, their families, and physicians for the management of congenital adrenal hyperplasia.
Higher levels of aldosterone are associated with insulin resistance and incident type 2 diabetes among multiethnic individuals.
Investigators sought to determine the frequency of metabolic syndrome in patients with nonfunctioning adrenal incidentalomas.
Results from this single-arm, open-label study found that 30% of patients achieved normalization of mean urinary free cortisol (UFC) after 6 months of maintenance treatment with levoketoconazole, without a dose increase (P<.25).
Azedra should be used by or under the control of physicians who are qualified by specific training and experience in the safe use and handling of radiopharmaceuticals.
Administering glucocorticoid leads to entrainment of molecular clocks in human peripheral blood mononuclear cells by regulating BMAL-1 and PER2-3.
Researchers assessed disease presentation and clinical outcomes in an older population of individuals with Cushing disease.
On laboratory tests, the authors identified an unusual endocrine hormonal profile, including pituitary hormones below reference intervals and gonadal and adrenal hormones above reference intervals.
