SPIRIVA RESPIMAT Rx
Generic Name and Formulations:
Tiotropium (as bromide monohydrate) 1.25mcg, 2.5mcg; per actuation; inh spray; contains benzalkonium chloride.
Boehringer Ingelheim Pharmaceuticals
Indications for SPIRIVA RESPIMAT:
Long-term maintenance treatment of bronchospasm due to COPD, including chronic bronchitis and emphysema. To reduce exacerbations of COPD. Long-term maintenance treatment of asthma in patients ≥6yrs of age.
COPD: 2 inh of Spiriva Respimat 2.5mcg/actuation (5mcg) once daily. Asthma: 2 inh of Spiriva Respimat 1.25mcg/actuation (2.5mcg) once daily; may take up to 4–8 weeks for max benefits. Max: 2 inh/24hrs.
Asthma: <6yrs: not established. ≥6yrs: 2 inh of Spiriva Respimat 1.25mcg/actuation (2.5mcg) once daily; may take up to 4–8 weeks for max benefits. Max: 2 inh/24hrs.
Allergy to ipratropium.
Not for the relief of acute symptoms. Discontinue if immediate hypersensitivity reactions (eg, angioedema) or paradoxical bronchospasm occurs; consider alternative therapy. Monitor for signs/symptoms of worsening narrow-angle glaucoma or worsening urinary retention (esp. GI or GU obstruction). Moderate-to-severe renal impairment; monitor for anticholinergic effects. Allergy to atropine or its derivatives; monitor. HandiHaler: avoid getting powder into eyes; or allergy to milk proteins. Pregnancy. Nursing mothers.
Avoid other anticholinergics.
Upper respiratory tract infection, dry mouth, sinusitis, pharyngitis, bronchitis, cough, headache, non-specific chest pain, UTI, dyspepsia, rhinitis, other anticholinergic effects (eg, urinary retention, constipation, dysuria, tachycardia, blurred vision, glaucoma); paradoxical bronchospasm.
HandiHaler (caps w. inh device)—5, 30, 90; Respimat (cartridge w. inh device)—4g (60 inh)
Endocrinology Advisor Articles
- GLP-1 Agonists Superior to DPP-4 Inhibitors for Reducing HbA1c, Weight in T2D
- Effect of HbA1c and Perioperative Glucose on Postoperative Mortality
- Semaglutide May Be Useful for Treating Obesity in People Without Diabetes
- Once-Daily Oral Contraceptive for Men Shows Promise
- Reducing Total Daily Insulin Dose in T2D: 3-Meal vs 6-Meal Diet
- American College of Physicians Releases 4 Guidelines for HbA1c Targets in T2D
- Dyslipidemia Drug Indications
- No Difference in Weight Loss Outcomes With Low-Fat vs Low-Carbohydrate Diet
- Damaging Effects of Gastric Bypass Surgery on Bone Mass and Microarchitecture
- Gastric Bypass Surgery Linked to Increased Risk for Nonvertebral Fractures
- Effect of High Androgen Levels on Cardiovascular Risk in Postmenopausal Women
- Fertility in Women Negatively Affected by Asthma Medications
- Glucocorticoid Use in COPD Does Not Increase Fracture Risk
- Drug Copayments Often Cost More Than Prescription Drugs
- Closed-Loop Insulin Delivery Offers Best Outcomes for Pregnant Women With T1D