Drug Name:
SINOGRAFIN Rx

Generic Name and Formulations:
Diatrizoate meglumine 527mg, iodipamide meglumine 268mg; per mL; soln for intrauterine instillation; contains sodium 0.91mg/mL, organically bound iodine 380mg/mL.
Company:
Bracco Diagnostics
Therapeutic Use:
Indications for SINOGRAFIN:
Hysterosalpingography.
Adult:
See literature for information on administration and radiography. Empty bladder before exam. 3–4mL administered in fractional doses of approx. 1mL are usually adequate to visualize the uterus; an additional 3–4mL will demonstrate the tubes. Total doses of 1.5–10mL have been used.
Children:
Not established.
Contraindications:
Pregnancy. During menstrual period. External genitalia or genital tract infection. Within 30 days of curettage or conization or within 6 months following termination of pregnancy.
Warnings/Precautions:
Should be performed by personnel trained in diagnostic procedures that involve radiopaque diagnostic agents. Carcinoma of the uterus and/or uterine/tubes; possible dispersion of carcinogenic cells during procedure. History of asthma/allergy. Nursing mothers.
Interactions:
May interfere with thyroid tests.
Pharmacological Class:
Radiopaque contrast medium.
Adverse Reactions:
Dizziness, syncope, hypotension, chills, fever, nausea, vomiting, abdominal pain and tenderness, hypersensitivity reactions; rare: bradycardia, hypotension, cardiac arrest, death.
How Supplied:
Single-dose vial (10mL)—10
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