Pregnancy

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D

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Pregnant women with T1D who received MDI therapy had a larger decrease in HbA1c levels and were less likely to report gestational hypertension, neonatal hypoglycemia, and NICU admissions than women who used insulin pump therapy during pregnancy.

Mistaking Legal Recourse for Evidence-Based Medical Practices in Surrogacy

Mistaking Legal Recourse for Evidence-Based Medical Practices in Surrogacy

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Paying a surrogate to carry a fetus shoehorns a fourth, and fifth, party into the already tight therapeutic triangle formed by the biological mom, fetus, and physician.

Treatment of Subclinical Hypothyroidism Not Warranted During Pregnancy

Treatment of Subclinical Hypothyroidism Not Warranted During Pregnancy

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Current trial evidence does not support the treatment of subclinical hypothyroidism diagnosed in pregnancy.

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

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Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.

Risk for Congenital Anomaly With Exposure to Insulin Analogues in the First Trimester

Risk for Congenital Anomaly With Exposure to Insulin Analogues in the First Trimester

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Results suggest that first trimester use of insulin analogues does not increase the risk for a congenital anomaly in women with diabetes compared with the use of human insulin.

Risk for Childhood Obesity Increased With Low Maternal Vitamin D Levels

Risk for Childhood Obesity Increased With Low Maternal Vitamin D Levels

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Researchers evaluated the association between low maternal vitamin D status in early pregnancy and the likelihood of childhood obesity in the offspring.

Metformin May Improve Pregnancy Outcomes in Polycystic Ovary Syndrome

Metformin May Improve Pregnancy Outcomes in Polycystic Ovary Syndrome

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Metformin treatment during pregnancy may improve outcomes in women with polycystic ovary syndrome.

Children Exposed to Metformin In Utero Have Increased Risk of Being Overweight

Children Exposed to Metformin In Utero Have Increased Risk of Being Overweight

Children exposed to metformin had higher BMI and increased prevalence of overweight/obesity at 4 years of age.

Sleeve Gastrectomy May Reduce Rates of Gestational Diabetes, Excessive Fetal Growth

Sleeve Gastrectomy May Reduce Rates of Gestational Diabetes, Excessive Fetal Growth

Researchers conducted a retrospective case-control study of deliveries that happened from 2006 to 2016 to examine associations of laparoscopic sleeve gastrectomy with maternal and perinatal outcomes.

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

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High-quality studies are needed to determine whether tight intrapartum glycemic control is superior to more relaxed glycemic targets intrapartum for women with diabetes in pregnancy.

Pregnancy Outcomes With Levothyroxine in Women Positive for Antithyroperoxidase Antibodies

Pregnancy Outcomes With Levothyroxine in Women Positive for Antithyroperoxidase Antibodies

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Levothyroxine treatment did not appear to improve pregnancy outcomes in women with thyroid autoantibodies undergoing in vitro fertilization and embryo transfer.

Risk for Congenital Malformations With Antithyroid Drugs

Risk for Congenital Malformations With Antithyroid Drugs

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Antithyroid drug exposure during the first trimester was associated with an increased risk for congenital malformations.

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

Women With T1D, T2D Receiving Increased Intervention in Pregnancy

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Higher rates of operative delivery and falling gestational age at delivery suggest that this is either reflected by, or despite, increasing obstetric intervention.

Breastfeeding May Lower Risk of Diabetes

Breastfeeding May Lower Risk of Diabetes

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Findings may have implications for social policies to extend paid maternity leave to achieve higher intensity and longer duration of breastfeeding.

Higher Risk for Adverse Pregnancy Outcomes in Women With Pregestational Diabetes on Metformin

Higher Risk for Adverse Pregnancy Outcomes in Women With Pregestational Diabetes on Metformin

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Higher risks for adverse pregnancy outcomes observed in pregnant women taking metformin for pregestational diabetes are not a result of metformin, but diabetes.

First trimester exposure to antithyroid drugs associated with increased risk of birth defects

First trimester exposure to anytithyroid drugs was associated with a greater risk of congenital malformations, especially for pregnant women who were given prescriptions for methimazole or both methimazole and propylthiouracil.

Longer lactation duration linked to lower risk of diabetes in women

In this 30-year prospective cohort study, self-reported duration of lactation in women of childbearing age was associated with a lower risk of development of diabetes.

Live-birth rates similar among ovulating women undergoing fresh- or frozen-embryo transfer

No differences were observed in live-birth rate, rates of implantation, clinical pregnancy, overall pregnancy loss, or ongoing pregnancy incidents between ovulatory women with infertility who received frozen-embryo or fresh-embryo transfers.

Postpartum Hypertension in Preeclampsia: Do Puerperal NSAIDs Effect Risk?

Postpartum Hypertension in Preeclampsia: Do Puerperal NSAIDs Effect Risk?

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Investigators encourage further research on the use of NSAIDs in women with preeclampsia who develop postpartum hypertension.

Maternal Thyroid-Stimulating Hormone, Free Thyroxine Associated With BMI

Maternal Thyroid-Stimulating Hormone, Free Thyroxine Associated With BMI

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Maternal thyroid function and weight gain in early pregnancy were associated with hypothyroidism, but not hyperthyroidism.

Risk Factors for Preeclampsia and Pregnancy-Associated Stroke in Women

Risk Factors for Preeclampsia and Pregnancy-Associated Stroke in Women

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Pregnancy-associated stroke risk is even higher in women with chronic hypertension, coagulopathies, and prothrombotic conditions.

Preventing Preterm Preeclampsia in At-Risk Women

Preventing Preterm Preeclampsia in At-Risk Women

Researchers examined the efficacy of aspirin in preventing preterm preeclampsia in women at risk.

Examining Health And Economic Burdens of Preeclampsia on Mothers, Children

Examining Health And Economic Burdens of Preeclampsia on Mothers, Children

Financial data for both mothers and children were examined through the first year of life.

Best Practices in Preconception Care in Pregestational Diabetes

Best Practices in Preconception Care in Pregestational Diabetes

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Special considerations are needed when treating women of reproductive age with pregestational diabetes.

Gestational Weight Gain Linked to Adverse Outcomes

Gestational Weight Gain Linked to Adverse Outcomes

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Gestational weight gain above current recommendations was a risk of infants with macrosomia or needing a cesarian delivery.

Hypertension in Pregnancy: Are Antihypertensive Agents Safe?

Hypertension in Pregnancy: Are Antihypertensive Agents Safe?

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According to Journal of the American Heart Association, pregnant women with chronic hypertension using antihypertensive agents reduces the risk of hypertension without added risk to the fetus.

Maternal Overweight, Obesity Linked to Increase in Fetal Birth Defects

Maternal Overweight, Obesity Linked to Increase in Fetal Birth Defects

Researchers suggest that women with overweight or obesity aim to lose weight before becoming pregnant.

Maternal Type 2 and Gestational Diabetes Lead to Increased Asthma Risk for Offspring

Maternal Type 2 and Gestational Diabetes Lead to Increased Asthma Risk for Offspring

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Researchers examined the relationship between maternal diabetes and asthma risk in children.

Risks Associated With Anticoagulant Use in Pregnancy

Risks Associated With Anticoagulant Use in Pregnancy

Vitamin K antagonists and low-molecular weight heparin were associated with the lowest risks of adverse maternal and fetal outcomes.

Increased Risk of Stroke in Preeclampsia With Hypertension, Infection

Increased Risk of Stroke in Preeclampsia With Hypertension, Infection

Women with preeclampsia should heed any neurological symptoms, which may be signs of a stroke.

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