Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.
Results suggest that first trimester use of insulin analogues does not increase the risk for a congenital anomaly in women with diabetes compared with the use of human insulin.
Researchers evaluated the association between low maternal vitamin D status in early pregnancy and the likelihood of childhood obesity in the offspring.
Metformin treatment during pregnancy may improve outcomes in women with polycystic ovary syndrome.
Children exposed to metformin had higher BMI and increased prevalence of overweight/obesity at 4 years of age.
Researchers conducted a retrospective case-control study of deliveries that happened from 2006 to 2016 to examine associations of laparoscopic sleeve gastrectomy with maternal and perinatal outcomes.
High-quality studies are needed to determine whether tight intrapartum glycemic control is superior to more relaxed glycemic targets intrapartum for women with diabetes in pregnancy.
Levothyroxine treatment did not appear to improve pregnancy outcomes in women with thyroid autoantibodies undergoing in vitro fertilization and embryo transfer.
Antithyroid drug exposure during the first trimester was associated with an increased risk for congenital malformations.
Higher rates of operative delivery and falling gestational age at delivery suggest that this is either reflected by, or despite, increasing obstetric intervention.
Findings may have implications for social policies to extend paid maternity leave to achieve higher intensity and longer duration of breastfeeding.
Higher risks for adverse pregnancy outcomes observed in pregnant women taking metformin for pregestational diabetes are not a result of metformin, but diabetes.
First trimester exposure to anytithyroid drugs was associated with a greater risk of congenital malformations, especially for pregnant women who were given prescriptions for methimazole or both methimazole and propylthiouracil.
In this 30-year prospective cohort study, self-reported duration of lactation in women of childbearing age was associated with a lower risk of development of diabetes.
No differences were observed in live-birth rate, rates of implantation, clinical pregnancy, overall pregnancy loss, or ongoing pregnancy incidents between ovulatory women with infertility who received frozen-embryo or fresh-embryo transfers.
Investigators encourage further research on the use of NSAIDs in women with preeclampsia who develop postpartum hypertension.
Maternal thyroid function and weight gain in early pregnancy were associated with hypothyroidism, but not hyperthyroidism.
Pregnancy-associated stroke risk is even higher in women with chronic hypertension, coagulopathies, and prothrombotic conditions.
Researchers examined the efficacy of aspirin in preventing preterm preeclampsia in women at risk.
Financial data for both mothers and children were examined through the first year of life.
Special considerations are needed when treating women of reproductive age with pregestational diabetes.
Gestational weight gain above current recommendations was a risk of infants with macrosomia or needing a cesarian delivery.
According to Journal of the American Heart Association, pregnant women with chronic hypertension using antihypertensive agents reduces the risk of hypertension without added risk to the fetus.
Researchers suggest that women with overweight or obesity aim to lose weight before becoming pregnant.
Researchers examined the relationship between maternal diabetes and asthma risk in children.
Vitamin K antagonists and low-molecular weight heparin were associated with the lowest risks of adverse maternal and fetal outcomes.
Women with preeclampsia should heed any neurological symptoms, which may be signs of a stroke.
Women at high risk for preeclampsia should take low-dose aspirin as a preventive therapy.
Miscarriage risk before 20 weeks of gestation is higher among women with untreated subclinical hypothyroidism.
The relative risk for developing preeclampsia, determined using waist-to-hip ratio, was 3.317 vs 2.418 using BMI.
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