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Physiologic Approaches to Optimizing Glycemic Control: A CME Symposium on Long-Acting Insulins

Physiologic Approaches to Optimizing Glycemic Control: A CME Symposium on Long-Acting Insulins


Patient Case Study

Time to Complete

1.50 hours


April 24, 2017


April 24, 2018
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Maximum Credits

1.50 / AMA PRA Category 1 CreditTM
1.50 / CPEU for Registered Dietitians/Registered Dietetic Technicians

Accredited Provider

Provided by Haymarket Medical Education

Commercial Supporter

Supported by an educational grant from Sanofi US

Program Description

Timely initiation and appropriate use of basal insulin can be critical elements in the care of patients with type 2 diabetes mellitus (T2DM). This activity focuses on use of the newer basal insulins whose pharmacokinetic and pharmacodynamic profiles better replicate endogenous patterns of insulin secretion compared with older agents in this class. The newer basal insulins are also associated with substantially lower risk for hypoglycemia, particularly nocturnal hypoglycemia.

Intended Audience

Internal medicine physicians and other healthcare providers who manage the care of patients with type 2 diabetes mellitus

Educational Objectives

At the conclusion of this activity, participants should be better able to:

  • Identify patients with type 2 diabetes mellitus (T2DM) who are candidates for basal insulin use
  • Implement strategies to overcome patient and provider reluctance to initiate and advance insulin therapy
  • Differentiate among basal insulins with regard to their pharmacokinetic and pharmacodynamic profiles and how closely they can replicate insulin secretion in healthy individuals
  • Develop individualized treatment plans that minimize hypoglycemia risk in T2DM

Conflict Of Interest Disclosure Policy

In accordance with the ACCME Standards for Commercial Support, HME requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. HME resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational activities.


Javier Morales, MD, FACP, FACE (Chair)
Clinical Associate Professor of Medicine
Hofstra Northwell School of Medicine at Hofstra University
Hempstead, NY
Vice President
Advanced Internal Medicine Group, PC
East Hills, NY

Dr. Morales receives consulting fees from and is on the speakers’ bureaus for Abbott Laboratories, Eli Lilly and Company, Janssen Pharmaceuticals, and Novo Nordisk Inc.

Daniel Einhorn, MD, FACP, FACE
Medical Director
Scripps Whittier Diabetes Institute
San Diego, CA
Clinical Professor of Medicine
University of California, San Diego
Clinical Endocrinologist
Diabetes and Endocrine Associates
La Jolla, CA

Dr. Einhorn receives consulting fees from Abbott Laboratories, Adocia, Eli Lilly and Company, Epitracker, GlySens Incorporated, Halozyme Therapeutics, Intarcia Therapeutics, Inc., Janssen Pharmaceuticals, Novo Nordisk Inc., Sanofi US, and Takeda Pharmaceutical Company. He also receives research grants from AstraZeneca, Bristol-Myers Squibb, Eisai Co., Ltd., Eli Lilly and Company, Janssen Pharmaceuticals, Mylan, Inc., Novo Nordisk Inc., and Sanofi US. Dr. Einhorn has ownership interests in Epitracker, GlySens Incorporated, Halozyme Therapeutics, and Nexus BioPharma, Inc.

Jeremy Pettus, MD
Assistant Professor of Medicine
Division of Endocrinology
University of California, San Diego
Director, Type 1 Diabetes
Taking Control of Your Diabetes
San Diego, CA

Dr. Pettus receives consulting fees from Dexcom, Inc., Insulet Corporation, MannKind Corporation, Novo Nordisk Inc., Sanofi US, and Valeritas, Inc., and is on the speakers’ bureau for Sanofi US.

Accredited Provider Disclosure

Haymarket Medical Education staff involved in the planning and content review of this activity have no relevant financial relationships to disclose.




AMA PRA Category 1 Credit(s)TM

Accreditation Statement

Haymarket Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation Statement

Haymarket Medical Education designates this enduring material for a maximum of 1.50 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.




CPEU Credit

Accreditation Statement

The following activity has been approved by the ACCME, whose approval is recognized by the Commission on Dietetic Registration and, as such, RDs/DTRs will be able to receive 1.50 CPEU.

Disclosure of Unlabeled Use

This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient's medical condition.


The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Haymarket Medical Education and Sanofi US. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

If you have any questions relating to the accreditation of this activity, please contact


To obtain credit, a score of 70% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.

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Hardware and Software Requirements
  • A computer with an internet connection
  • Internet Browser: Internet Explorer 7.x or higher, Firefox 4.x or higher, Safari 2.x or higher, or any other W3C standards compliant browser
  • Additional Software: Adobe Flash Player and/or an HTML 5 capable browser maybe required for video or audio playback. PowerPoint or Adobe Acrobat Reader may occasionally be required
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