Pediatric Endocrinology

Adipokines Associated With Clinical Course Alteration in Pediatric Patients With T1D

Adipokines Associated With Clinical Course Alteration in Pediatric Patients With T1D

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Altered serum levels of nicotinamide phosphoribosyltransferase, omentin-1, and caspase-cleaved cytokeratin 18 fragment M30 in children with type 1 diabetes may signify metabolic differences that do not stabilize with insulin treatment.

Executive Function Predicts T1D Management Into Emerging Adulthood

Executive Function Predicts T1D Management Into Emerging Adulthood

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Individuals with higher executive function performance at baseline experienced slower increases in HbA1c.

Child Participation in Medicaid, CHIP Up From 2013 to 2016

Child Participation in Medicaid, CHIP Up From 2013 to 2016

From 2013 to 2016 there was an increase in children's participation in Medicaid and the Children's Health Insurance Program.

Higher Risk for Meningioma Linked to GH Treatment, Radiotherapy During Childhood

Higher Risk for Meningioma Linked to GH Treatment, Radiotherapy During Childhood

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The risk for meningioma was not significantly higher in patients who did not receive radiotherapy.

"Is It Just a Phase?" What to Do When Transgender Youths Ask to Transition

"Is It Just a Phase?" What to Do When Transgender Youths Ask to Transition

In the last 5 years, many clinicians have faced tough questions about how best to serve transgender youth while doing no harm.

Effect of Birth Weight and Rapid Weight Gain During Infancy on Insulin Sensitivity

Effect of Birth Weight and Rapid Weight Gain During Infancy on Insulin Sensitivity

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Investigators sought to determine the effect of birth weight, weight gain from 0 to 2 years, and adiposity on insulin resistance and sensitivity in early adolescence.

Grote Clinical Decision Rule May Be Best for Monitoring Growth in Children

Grote Clinical Decision Rule May Be Best for Monitoring Growth in Children

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Investigators sought to improve growth-monitoring programs by examining existing algorithms and examined the effect of using WHO vs national growth charts on algorithm performance.

Counseling Needed for Pediatric Patients With Impaired Fertility

Counseling Needed for Pediatric Patients With Impaired Fertility

Counseling about impaired fertility and sexual function for at-risk pediatric populations in developmentally appropriate ways is essential.

ASMBS Pediatric Committee Updates Guidelines on Bariatric Surgery in Teens

ASMBS Pediatric Committee Updates Guidelines on Bariatric Surgery in Teens

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The American Society for Metabolic and Bariatric Surgery Pediatric Committee has updated their 2012 evidence-based guidelines.

Appetite Awareness Training May Enhance Behavioral Strategies in Childhood Obesity

Appetite Awareness Training May Enhance Behavioral Strategies in Childhood Obesity

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The lifestyle physical activity program included weight education, control, self-monitoring, behavioral change techniques, and maintenance of behavior change.

Two-Screen Program More Effective for Identifying Congenital Hypothyroidism

Two-Screen Program More Effective for Identifying Congenital Hypothyroidism

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There are 14 states that perform a routine second screening in infants at approximately 2 weeks of age.

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

ADA Releases Updated Guidelines for Managing Pediatric Type 1 Diabetes

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It is critical for us to remember that children are not little adults. Pediatric-onset diabetes is different from adult-onset diabetes due to its distinct epidemiology, pathophysiology, developmental considerations, and response to therapy.

Smoothing the Care Team Transition for Youth With Type 1 Diabetes

Smoothing the Care Team Transition for Youth With Type 1 Diabetes

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The transition from pediatric to adult care for type 1 diabetes should be a gradual process, with a plan to make the change when the patient is ready, not at a pre-determined time.

Idiopathic Short Stature: Expert Perspectives

Idiopathic Short Stature: Expert Perspectives

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Guidelines from The Endocrine Society, updated in 2017, advocate a shared decision-making approach regarding growth hormone therapy and advise against routine treatment for all children with idiopathic short stature.

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

ISPAD Issues Consensus Statement on Diabetic Ketoacidosis and Hyperglycemia

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ISPAD recommends adjustments for fluid management regarding rehydration rates in children and adolescents with diabetes ketoacidosis.

MiniMed 670G System Approved for Use in Younger Patients With T1D

MiniMed 670G System Approved for Use in Younger Patients With T1D

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The MiniMed 670G system measures glucose levels every 5 minutes and automatically adjusts insulin delivery to avoid highs and lows.

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

Safety and Performance of Omnipod HCL for Children With Type 1 Diabetes

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In children with type 1 diabetes, the Omnipod hybrid closed-loop personal model system was safe and performed well.

Metabolic Health Predicative of Cognitive Development in Children

Metabolic Health Predicative of Cognitive Development in Children

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Researchers assessed whether current metabolic parameters are inversely associated with cognitive functioning.

Effect of Infant Feeding Practices and Gut Microbiota on Overweight in First Year

Effect of Infant Feeding Practices and Gut Microbiota on Overweight in First Year

Researchers assessed the effect of formula supplementation vs breastfeeding on the gut microbiome and risk of infant overweight.

Burosumab May Benefit Children With X-Linked Hypophosphatemia

Burosumab May Benefit Children With X-Linked Hypophosphatemia

Subcutaneous burosumab decreases mean Thacher rickets severity total score from dosing every two weeks or every four weeks.

Increased Risk for Type 2 Diabetes in Adolescents, Young Adults With ADHD

Increased Risk for Type 2 Diabetes in Adolescents, Young Adults With ADHD

These findings can inform clinical practice in that type 2 diabetes should be considered in ADHD even in the absence of other known risk factors.

Childhood Overweight Increases Risk for Type 2 Diabetes in Adulthood

Childhood Overweight Increases Risk for Type 2 Diabetes in Adulthood

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Investigators examined changes in weight from childhood to early adulthood and the risk for developing type 2 diabetes.

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

Glycemic Control Variations for Children, Adolescents With T1D in High-Income Countries

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Investigators examined glycemic control variations in 8 high-income countries from multicenter registries in children with type 1 diabetes.

Effect of Maternal Caffeine Intake on Childhood Growth

Effect of Maternal Caffeine Intake on Childhood Growth

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Maternal caffeine intake >200 mg/day during pregnancy was associated with high weight gain velocity beginning from the first months of life and higher BMI throughout childhood.

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

Exceptional Glycemic Control With Very Low-Carbohydrate Diet

For children and adults with type 1 diabetes, consuming a very low-carbohydrate diet is associated with exceptional glycemic control.

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

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Routine screening for neonatal hypoglycemia after pregnancies complicated by gestational diabetes (GD) reveals high incidence of both mild and severe hypoglycemia for both diet-controlled and insulin-treated GD and across the full range of birth weight centiles.

Childhood Insulin Resistance Associated With Later Psychosis

Childhood Insulin Resistance Associated With Later Psychosis

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The authors advised clinicians to carefully consider which antipsychotics they prescribe their patients with metabolic dysfunction, as some are known to be diabetogenic.

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

Mitochondrial, Muscle Ultrastructural Abnormalities Observed in Skeletal Muscle of Young Adults With T1D

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The study highlights mitochondrial and autophagic differences in the muscles of young adults with type 1 diabetes with moderate glycemic control who exceed recommended activity levels.

Risk for Iodine Deficiency and Hypothyroidism High in Children on Parenteral Nutrition

Risk for Iodine Deficiency and Hypothyroidism High in Children on Parenteral Nutrition

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Study is the first to reveal a higher prevalence of iodine deficiency and hypothyroidism in children receiving chronic parenteral nutrition.

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

Risk for Fetal Loss Early in Pregnancy Not Greater With Noninsulin vs Insulin Therapy

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Compared to standard insulin treatment, noninsulin antidiabetic agents did not present an increased risk for fetal losses or major malformations when used in the first trimester of pregnancy.

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