Pediatric Endocrinology

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"Is It Just a Phase?" What to Do When Transgender Youths Ask to Transition

"Is It Just a Phase?" What to Do When Transgender Youths Ask to Transition

In the last 5 years, many clinicians have faced tough questions about how best to serve transgender youth while doing no harm.

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Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

Safety and Mortality Outcomes Following Pediatric Growth Hormone Therapy

Primary cancer rates and mortality risk were no higher for pediatric patients treated with growth hormone therapy.

Higher Risk for Meningioma Linked to GH Treatment, Radiotherapy During Childhood

Higher Risk for Meningioma Linked to GH Treatment, Radiotherapy During Childhood

The risk for meningioma was not significantly higher in patients who did not receive radiotherapy.

Grote Clinical Decision Rule May Be Best for Monitoring Growth in Children

Grote Clinical Decision Rule May Be Best for Monitoring Growth in Children

Investigators sought to improve growth-monitoring programs by examining existing algorithms and examined the effect of using WHO vs national growth charts on algorithm performance.

Following Approval, Triptorelin 6-Month Injection Now Available to Treat Central Precocious Puberty

Following Approval, Triptorelin 6-Month Injection Now Available to Treat Central Precocious Puberty

Gonadotropin-releasing hormone (GnRH) agonist Triptodur treats central precocious puberty via intramuscular injection.

FDA: Triptorelin Slows Central Precocious Puberty

FDA: Triptorelin Slows Central Precocious Puberty

Data from a phase 3 clinical trial found that triptorelin achieved positive results in patients age 2 and older with central precocious puberty.

Growth Hormone Does Not Impact Glucose Homeostasis in Turner Syndrome

Growth Hormone Does Not Impact Glucose Homeostasis in Turner Syndrome

Treatment with growth hormone did not affect insulin sensitivity or insulin secretion in girls with Turner syndrome.

Precocious Puberty More Common in Girls Than Boys

Precocious Puberty More Common in Girls Than Boys

Ovarian cyst and McCune-Albright syndrome were most responsible for the increased risk of non-congenital adrenal hyperplasia gonadotropin-independent precocious puberty.

Metformin Linked to Increased Height in Children, Teens

Metformin Linked to Increased Height in Children, Teens

In larger doses, the diabetes drug may increase height in children and adolescents.

Longer-Term Histrelin Safe, Effective for Central Precocious Puberty

Longer-Term Histrelin Safe, Effective for Central Precocious Puberty

Long-term treatment with the histrelin implant safely and effectively sustained gonadotropin suppression and improved predicted adult height in central precocious puberty.

Ferring to Launch Pediatric Endo Products Zomacton and Zoma-Jet Soon

Ferring to Launch Pediatric Endo Products Zomacton and Zoma-Jet Soon

Ferring announced that the FDA has approved the name changes of its newly acquired products to be marketed as Zomacton (somatropin [rDNA origin]; formerly Tev-Tropin) for injection, and the needle-free delivery system as Zoma-Jet (formerly Tjet).

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