Pediatric Endocrinology

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Growth and Development Differences During Puberty in Children With T1D

Growth and Development Differences During Puberty in Children With T1D

Study showed gender-discordant metabolic impairment during puberty that was correlated with peak growth velocity in boys, but not in girls.

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Burosumab May Benefit Children With X-Linked Hypophosphatemia

Burosumab May Benefit Children With X-Linked Hypophosphatemia

Subcutaneous burosumab decreases mean Thacher rickets severity total score from dosing every two weeks or every four weeks.

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

Routine screening for neonatal hypoglycemia after pregnancies complicated by gestational diabetes (GD) reveals high incidence of both mild and severe hypoglycemia for both diet-controlled and insulin-treated GD and across the full range of birth weight centiles.

Vitamin D Insufficiency Associated With Insulin Resistance Independent of Obesity in Children

Vitamin D Insufficiency Associated With Insulin Resistance Independent of Obesity in Children

Further clinical trials are needed to explore the potential beneficial effect of vitamin D supplementation, via fortified foods and/or dietary supplements, on insulin resistance, and possibly on weight management.

Obesity Risk in Infants Born to Women With Diabetes

Obesity Risk in Infants Born to Women With Diabetes

Parents and healthcare workers should carefully consider the risk for obesity in infants born to women with diabetes, especially infants born large for gestational age, and should initiate preventive measures where possible.

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Risk Factors for Cardiovascular Disease in Youth With Type 1 Diabetes

Early treatment of cardiovascular disease risk factors such as dyslipidemia and hypertension will have long-term benefits with low risk and cost and should be more widely used in pediatric type 1 diabetes care.

Incidence of Diabetes Insipidus in Children Following Transsphenoidal Surgery

Incidence of Diabetes Insipidus in Children Following Transsphenoidal Surgery

Findings demonstrated a high incidence of sodium alterations in children following transsphenoidal surgery, with a 38% combined incidence of diabetes insipidus and syndrome of inappropriate antidiuretic hormone secretion.

Repeat Blood Pressure Readings in Children Prevents Unnecessary Follow-up

Repeat Blood Pressure Readings in Children Prevents Unnecessary Follow-up

Only approximately half of pediatric patients with a blood pressure reading ≥95th percentile would be correctly classified based on their initial blood pressure reading.

Trends in CVD, Risk Factors, and Medications in Children With T1D

Trends in CVD, Risk Factors, and Medications in Children With T1D

Children with T1D had statistically significantly higher prevalence rates of hypertension, hypercholesterolemia, and used more CV medication compared with a matched diabetes-free reference cohort in the period after the onset of diabetes.

Systemic Corticosteroid Use May Increase Fracture Risk in Pediatric Asthma

Systemic Corticosteroid Use May Increase Fracture Risk in Pediatric Asthma

Increased odds of fractures in pediatric patients with asthma may be associated with systemic corticosteroid use, but not with inhaled corticosteroid use.

Trabecular Bone Morphology Changes May Predict Bone Strength in Girls

Trabecular Bone Morphology Changes May Predict Bone Strength in Girls

Study investigated the correlations between age and body composition with trabecular morphology in a cohort of healthy girls age 9 to 18.

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