Obesity

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Strategies to Prevent Obesity in Children

Strategies to Prevent Obesity in Children

Of various interventions used in nonclinical settings for the prevention of childhood overweight and obesity, school-based programs that combine nutrition and exercise and include a home-based component appear to be the most effective approaches.

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Obesity Risk in Infants Born to Women With Diabetes

Obesity Risk in Infants Born to Women With Diabetes

Parents and healthcare workers should carefully consider the risk for obesity in infants born to women with diabetes, especially infants born large for gestational age, and should initiate preventive measures where possible.

Oxyntomodulin Augments Glucose Homeostasis

Oxyntomodulin Augments Glucose Homeostasis

In obese subjects with and without type 2 diabetes, oxyntomodulin significantly augments glucose-dependent insulin secretion.

Waist-to-Height Ratio Tied to Anxiety in Middle-Aged Women

Waist-to-Height Ratio Tied to Anxiety in Middle-Aged Women

Researchers conducted secondary analysis of data from a multicenter study of 5580 women from 11 Latin America countries in order to assess the association between waist-to-height ratio and anxiety.

No association of overweight childhood and adult type 2 diabetes risk after weight loss

Compared to men who were never overweight, those overweight at age 7 who returned to a normal body mass index by age 13 had no increased risk for developing type 2 diabetes.

Increased Risk for Abdominal Obesity Found in People Living With HIV

Increased Risk for Abdominal Obesity Found in People Living With HIV

The Copenhagen Co-morbidity in HIV Infection (COCOMO) study assessed the association between risk factors for cardiovascular disease and HIV infection.

Factors Identified for Breastfeeding Behavior in Women With BMI ≥30

Factors Identified for Breastfeeding Behavior in Women With BMI ≥30

Current care should encourage women to plan to breastfeed, provide corrective information for specific beliefs, and address issues relating to body image and social knowledge.

Weight Loss Over Time May Reduce Risk for Diabetes Onset

Weight Loss Over Time May Reduce Risk for Diabetes Onset

The findings from a national sample underscore the importance of developing policies and programs that reduce the prevalence of obesity.

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Eating Pecans May Cut Risk for Cardiovascular Disease, Diabetes

Changes in serum insulin and homeostatic model assessment of insulin resistance and beta cell function were significantly greater compared to the control diet

BMI As Predictor of CVD Risk May Be More Susceptible to Bias

BMI As Predictor of CVD Risk May Be More Susceptible to Bias

The J-shaped correlation seen for body mass index with cardiovascular disease risk is susceptible to confounding due to pre-existing comorbidities.

Overweight, Obesity Contributing to Cancers in Young Adults

Overweight, Obesity Contributing to Cancers in Young Adults

Researchers conducted a comprehensive narrative review to examine the correlation of the obesity pandemic with appearance of cancers in young adults under age 50.

Association Between BMI-Related Metabolites, Gut Microbiota, and Obesity

Association Between BMI-Related Metabolites, Gut Microbiota, and Obesity

Metabolites could be mediators in the connection between gut microbiota and obesity and points to potential future opportunities for targeting the gut microbiota in the prevention of obesity.

Change in BMI During Puberty Tied to Later Heart Failure Risk in Men

Change in BMI During Puberty Tied to Later Heart Failure Risk in Men

Change in body mass index to overweight during puberty significantly increases men's risk of heart failure later in life.

Strategies to Prevent Obesity in Children

Strategies to Prevent Obesity in Children

Of various interventions used in nonclinical settings for the prevention of childhood overweight and obesity, school-based programs that combine nutrition and exercise and include a home-based component appear to be the most effective approaches.

Obesity Linked to Improved Survival in Metastatic Melanoma

Obesity Linked to Improved Survival in Metastatic Melanoma

For men with metastatic melanoma treated with targeted or immune therapy, obesity is associated with improved survival.

BMI Linked to Hepatocellular Carcinoma Risk in Chronic Hepatitis B Virus

BMI Linked to Hepatocellular Carcinoma Risk in Chronic Hepatitis B Virus

For patients with chronic hepatitis B virus, body mass index is significantly associated with increased risk of hepatocellular carcinoma, with the risk more pronounced for women than men.

Cryoablation of Posterior Vagal Trunk Feasible in Obesity

Cryoablation of Posterior Vagal Trunk Feasible in Obesity

Following the success of this preliminary safety and feasibility study, more patients are being recruited for a larger clinical trial of the procedure to test the efficacy and durability of the procedure.

Independent Risk Pathways Shown for Diabetes and Obesity in Adults With Serious Mental Illness

Independent Risk Pathways Shown for Diabetes and Obesity in Adults With Serious Mental Illness

Given the high risk for metabolic disorder and type 2 diabetes, clinicians should select psychotropic medications carefully and monitor metabolic conditions regularly in their patients with serious mental illness.

Recent Years Have Seen Obesity Prevalence Increasing for Adults

Recent Years Have Seen Obesity Prevalence Increasing for Adults

For adults, but not youth, there was an increase in the prevalence of obesity in decade between 2007-2008 and 2015-2016.

Risk for Childhood Obesity Increased With Low Maternal Vitamin D Levels

Risk for Childhood Obesity Increased With Low Maternal Vitamin D Levels

Researchers evaluated the association between low maternal vitamin D status in early pregnancy and the likelihood of childhood obesity in the offspring.

Menopausal Hormone Therapy Linked to Reduced Abdominal Fat

Menopausal Hormone Therapy Linked to Reduced Abdominal Fat

Physicians should be aware that the benefit of menopausal hormone therapy (MHT) on body composition might rapidly disappear after its withdrawal and strongly encourage women to optimize nutrition and increase physical activity when stopping MHT.

Calorie Restriction Linked to Sustained Metabolic Adaptation

Calorie Restriction Linked to Sustained Metabolic Adaptation

Calorie restriction over 2 years is associated with considerable weight loss, and with lower than expected energy expenditure.

Surgical Treatment Better Than Medical Therapy in Severely Obese Adolescents With T2D

Surgical Treatment Better Than Medical Therapy in Severely Obese Adolescents With T2D

Researchers compared glycemic control in cohorts of severely obese adolescents with type 2 diabetes undergoing medical and surgical interventions.

Bariatric Surgery Underused in Adolescents With Severe Obesity

Bariatric Surgery Underused in Adolescents With Severe Obesity

Results comparing the prevalence of obesity amongst adolescents with the rate of bariatric surgeries were presented at ENDO 2018.

Semaglutide May Be Useful for Treating Obesity in People Without Diabetes

Semaglutide May Be Useful for Treating Obesity in People Without Diabetes

In combination with dietary and physical activity counseling, all semaglutide doses from 0.05-0.4 mg daily were tolerated and resulted in dose-related reductions in body weight among people with obesity without diabetes.

Reducing Total Daily Insulin Dose in T2D: 3-Meal vs 6-Meal Diet

Reducing Total Daily Insulin Dose in T2D: 3-Meal vs 6-Meal Diet

In people with obesity and type 2 diabetes, a meal schedule that includes a high-energy breakfast promotes weight loss, improves diabetes, and decreases the need for insulin.

Gastric Bypass Surgery Linked to Increased Risk for Nonvertebral Fractures

Gastric Bypass Surgery Linked to Increased Risk for Nonvertebral Fractures

Roux-en Y gastric bypass increased the likelihood of nonvertebral fractures, including hip, wrist, and pelvic fractures.

Separate Pathways for T2D and Obesity in Patients With Mental Illness

Separate Pathways for T2D and Obesity in Patients With Mental Illness

New research suggests that there are separate pathways for the development of type 2 diabetes and obesity in patients with serious mental illness and demonstrate that there are important effects associated with sex and race or ethnicity.

Weight Changes Influence Risk of Diabetes Over Course of Life

Weight Changes Influence Risk of Diabetes Over Course of Life

Changes in weight influence the risk of diabetes, with lower risk of diabetes for obese individuals who lose weight vs stable obesity.

Obesity May Increase Cardiovascular Morbidity, Mortality

Obesity May Increase Cardiovascular Morbidity, Mortality

Results provide critical perspective on cardiovascular disease associated with overweight and obesity and challenge both the obesity paradox as well as the view that overweight is associated with greater longevity.

No Difference in Weight Loss Outcomes With Low-Fat vs Low-Carbohydrate Diet

No Difference in Weight Loss Outcomes With Low-Fat vs Low-Carbohydrate Diet

There was no significant difference in 12-month weight loss between the healthy low-fat and low-carbohydrate diets, and neither genotype pattern nor baseline insulin secretion was associated with the dietary effects on weight loss.

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