Children with autism spectrum disorder (ASD) have increased odds of overweight/obesity compared with general population controls after adjustment for child co-occurring conditions.
Measures that quantified weight regain as a percentage of maximum weight lost had the strongest association and best fit with clinical outcomes.
The SAVE study was a multicenter, international clinical trial that tested the efficacy of continuous positive airway pressure and normal care in patients with sleep apnea.
Obesity rates are nearly 40% among US adults, but traditional treatment methods are found to contribute to weight stigma, creating a population that's unhealthier than ever.
Gastric banding and metformin resulted in similar improvements in insulin sensitivity in moderately obese adults with impaired glucose tolerance or mild T2D over a 2-year period.
From 2005 through 2014, an estimated 14,178 metabolic and bariatric surgery (MBS) procedures were performed among pediatric patients aged 20 years and younger with severe obesity.
The randomized, double-blind, placebo-controlled, parallel-group study (N = 9340) evaluated the time from randomization to first occurrence of major adverse CV events (MACE) (non-fatal heart attack, non-fatal stroke, CV death) in patients treated with liraglutide 1.8mg once daily or placebo.
High childhood body mass index is strongly correlated with slipped capital femoral epiphysis.
Obesity was not associated with more aggressive clinicopathologic features of thyroid cancer.
The United States will have the largest drop in life expectancy rankings of all high-income countries by 2040.
Children with asthma had a 66% higher risk for incident obesity compared with children without asthma.
For patients with severe obesity and type 2 diabetes, bariatric surgery is associated with a lower risk for macrovascular outcomes compared with not undergoing surgery.
Dietary supplements often include active pharmaceuticals, even after warnings from the U.S. Food and Drug Administration.
Heritability of BMI was significantly higher in children living in high-risk obesogenic environments compared with those living in low-risk environments.
Greater weight gain in early childhood often carries over to overweight and obesity in adolescence.
Girls with obesity in adolescence are associated with lower educational attainment and income-related outcomes compared with girls without adolescent obesity.
Investigators examine the effect of a low-fat, plant-based diet on insulin resistance and body composition.
Breastfeeding is inversely associated with body mass index z scores measured at 12 months, and the association is attenuated with formula supplementation by six months.
In this new analysis, researchers looked at the long-term effects of the drug on diabetes prevention and remission in these patients.
Obesity is associated with loss of disease-free years irrespective of position in the social hierarchy and lifestyle.
Roux-en-Y gastric bypass is associated with bone density and skeletal microarchitecture deterioration, leading to substantial cumulative bone loss.
Lorcaserin facilitates sustained weight loss without increasing the rate of major cardiovascular events among overweight or obese patients.
To understand the associations between exposure to gestational diabetes and the risk for maternal glucose metabolism and childhood adiposity, researchers followed a cohort of mothers and children for a median of 11.4 years.
For overweight/obese veterans with prediabetes, participation is higher for online Diabetes Prevention Programs, but weight loss is similar for online and in-person DPPs.
Lifestyle interventions focusing on diet and physical activity result in less excess gestational weight gain (GWG) among women with overweight and obesity.
Untreated gestational diabetes is associated with development of subsequent glucose metabolism disorders in mothers, but is not significantly associated with the composite outcome of childhood overweight/obesity in long-term follow-up of offspring.
Altered serum levels of nicotinamide phosphoribosyltransferase, omentin-1, and caspase-cleaved cytokeratin 18 fragment M30 in children with type 1 diabetes may signify metabolic differences that do not stabilize with insulin treatment.
The USPSTF recommends that clinicians refer adults with a body mass index of 30 or higher to intensive, multicompetent behavioral interventions.
Supplementation with n-3 long chain polyunsaturated fatty acids in pregnancy leads to higher body mass index (BMI) in offspring at age 6 years.
Significant negative correlations were seen between visceral fat area and bronchial lumen diameter and lumen area, and significant positive correlations were seen between subcutaneous fat area and bronchial wall area and total area.
The prevalence of obesity may be lower among drug-dependent individuals, particularly in those dependent on opioids, compared with the general population.
Investigators examined the weight loss effects of semaglutide compared with liraglutide in patients with obesity who do not have diabetes.
Investigators sought to determine whether geographic distribution of childhood obesity can inform and design the delivery of interventions.
Investigators examined the long-term associated between mortality risk and carbohydrate intake.
While antipsychotic treatments can improve behavioral symptoms, risk of hyperglycemia and weight gain should inform careful consideration of antipsychotic use in young patients.
Investigators assessed the effect of exercise modality during dietary-induced on bone health.
A low-energy diet for weight loss had different effects between men and women after weight reduction.
In the absence of obesity, patients with PTSD are not at an increased risk for type 2 diabetes.
Higher body mass index is likely to cause worse cardiovascular health in youth.
Investigators examined the effect of bariatric surgery and the incidence of microvascular complications in type 2 diabetes.
The American Society for Metabolic and Bariatric Surgery Pediatric Committee has updated their 2012 evidence-based guidelines.
Maternal prepregnancy obesity without pregestational diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) was associated with a slightly increased risk of having a child with a neurodevelopmental or psychiatric disorder.
American Heart Association science advisory recommends healthy eating patterns instead.
The lifestyle physical activity program included weight education, control, self-monitoring, behavioral change techniques, and maintenance of behavior change.
A 36-month multicomponent behavioral intervention does not change BMI trajectory.
The researchers noted that these findings highlight the complexity of obesity as a disease that shares a common etiology with some psychiatric and addictive disorders.
Exercising, eating less were top weight loss methods; more women than men attempted weight loss.
Higher body fat percentage, higher waist circumference, and obesity were associated with a greater risk for RA in women.
Investigators examine the influence of gender, sex hormones, and obesity on the composition of gut microbiota in women with PCOS.
Childhood obesity continues to be a public health issue that requires improved policies and interventions at both the individual and population level.
Patterns of self-regulation of toddlers and risk for obesity and whether they differ between boys and girls were examined.
Maternal adherence to a healthy lifestyle throughout children's childhood and adolescent years may result in a reduced risk for obesity.
Adherence to a healthy lifestyle among mothers during their offspring's childhood is associated with reduced risk of childhood obesity.
The AMA supports evidence-based strategies such as excise taxes and adding warning labels.
From 1988-1994 to 2009-2014 there has been an increase in prevalence of overweight/obesity, but a decrease in weight loss efforts.
Obesity has a substantial effect on general health parameters, but its role in rheumatoid arthritis is much more complex.
Psychiatric diagnoses may not be a contraindication to weight loss surgery.
Consumers with obesity report favoring taste and value rather than health and nutrition.
Increased obesity for men, women living in medium, small versus large metropolitan statistical areas
Investigators conducted a retrospective observational study to assess the impact of psychostimulant medication on BMI and height in a group of children and adolescents with ADHD.
Researchers assessed the effect of formula supplementation vs breastfeeding on the gut microbiome and risk of infant overweight.
The prevalence of obesity is higher among those living in non-metropolitan counties versus metropolitan counties.
Many working Americans obtain food and beverages from work, and these foods often do not align with dietary guidelines.
The researchers found that on a given day, 85 percent of infants and toddlers had any consumption of added sugar.
Researchers assessed current patterns of physical activity and duration among adolescents and young adults, as well as the direction and magnitude of associations between physical activity and income, race/ethnicity, and sex among participants in the National Health and Nutrition Examination Survey.
Increased adherence to healthy dietary patterns could result in health care savings from improved health outcomes.
Regardless of long-term metabolic health maintenance, obesity remains a risk factor for cardiovascular disease.
If current trends continue, one-third of children and one-half of adolescents will be obese or overweight by 2030.
Specifically, the new labeling includes updated data on the global rate of occurrence related to these adverse events.
Body mass index and body fat distribution may influence smoking behaviors.
Investigators assessed the effects of diazoxide on lipid and glucose metabolism in obese men with diabetes.
Physical activity modifies the association between the body mass index genetic risk score and BMI.
Investigators examined changes in weight from childhood to early adulthood and the risk for developing type 2 diabetes.
Endocrinologist Kevin M. Pantalone, DO, and psychiatrist Christian Kohler, MD, discuss the risk associated with the use of antipsychotic medications in individuals with type 2 diabetes.
Severe obesity is associated with more rapid progression of disability in rheumatoid arthritis.
Baseline obesity is associated with an increased risk for late-life mobility limitations in women undergoing joint replacement for OA.
In 2014, health care provider counseling for weight loss for adults with arthritis and overweight or obesity was 45.5 percent, up 10.4 percent from 2002.
Eesearchers found that baseline metabolically healthy obesity was not significantly associated with incident cardiovascular disease, compared with metabolically healthy normal weight.
Maternal caffeine intake >200 mg/day during pregnancy was associated with high weight gain velocity beginning from the first months of life and higher BMI throughout childhood.
Severely obese rheumatoid arthritis patients also had worse disability at baseline than overweight patients.
Researchers sought to determine the predictive value of tibiofemoral MRI, patellofemoral MRI, and KLG1 for the incidence of clinical or radiographic knee OA.
Based on findings from a systematic review of the literature, recommendations have been developed for improving the evidence for natural experiments in obesity.
Improved research methods needed to determine effectiveness of anti-obesity public health initiatives
Researchers found that amongst nearly 300 studies reporting the impact of policies, programs, or changes in built environment on controlling and preventing obesity, most natural experiments had high risk of bias and poor handling of dropouts and withdrawals.
Researchers assessed the weight stigma experiences of 1,513 men, examining the characteristics of men who experienced weight stigma versus men who did not.
Targeted diabetes screening based only on age and weight criteria will identify approximately half of US adults with dysglycemia.
Results suggest that circadian preference and meal timing are novel and possibly modifiable risk factors for obesity in type 2 diabetes.
A soda tax does influence daily consumption of regular soda, energy drinks, and bottled water.
Further clinical trials are needed to explore the potential beneficial effect of vitamin D supplementation, via fortified foods and/or dietary supplements, on insulin resistance, and possibly on weight management.
Ethnicity,race, markers of insulin resistance, and genetic factors might help identify obese youth at risk for developing fatty liver.
Researchers examined the relationship between early to mid-childhood adiposity measures and mid-childhood alanine aminotransferase levels.
For overweight or obese adults with T2D, a long-term weight loss intervention is associated with a reduction in long-term disability.
Parents and healthcare workers should carefully consider the risk for obesity in infants born to women with diabetes, especially infants born large for gestational age, and should initiate preventive measures where possible.
In obese subjects with and without type 2 diabetes, oxyntomodulin significantly augments glucose-dependent insulin secretion.
Researchers conducted secondary analysis of data from a multicenter study of 5580 women from 11 Latin America countries in order to assess the association between waist-to-height ratio and anxiety.
Compared to men who were never overweight, those overweight at age 7 who returned to a normal body mass index by age 13 had no increased risk for developing type 2 diabetes.
The Copenhagen Co-morbidity in HIV Infection (COCOMO) study assessed the association between risk factors for cardiovascular disease and HIV infection.
Current care should encourage women to plan to breastfeed, provide corrective information for specific beliefs, and address issues relating to body image and social knowledge.
The findings from a national sample underscore the importance of developing policies and programs that reduce the prevalence of obesity.
Changes in serum insulin and homeostatic model assessment of insulin resistance and beta cell function were significantly greater compared to the control diet
The J-shaped correlation seen for body mass index with cardiovascular disease risk is susceptible to confounding due to pre-existing comorbidities.
Endocrinology Advisor Articles
- Normalized HbA1c Levels Facilitate Improved Neuropathy Outcomes in T2D
- Hypothyroidism Treatment No Longer Available
- Endocrine-Disrupting Chemicals in Personal Care Products Linked to Early Puberty
- Serious Adverse Events Linked to SGLT2 Inhibitors
- Parental Perception of Child Weight Status Predicted by Child BMI z Scores
- Elevated Triglyceride Levels Affect Glycemic Control in Type 2 Diabetes
- ADA Issues Position Statement on Comprehensive Care for Pediatric T2D
- Type 1 Diabetes Confers Extra Risk for Autoimmune Diseases
- Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D
- Endocrine-Disrupting Chemicals in Personal Care Products Linked to Early Puberty
- A Risk Prediction Tool for Hip Fracture in Type 2 Diabetes
- Reduced Fertility in Obese Women May Be Related to Dysfunctional Insulin Pathway
- Prenatal Exposure to Famine Increases Risk for Early Menopause
- Most Insured Patients Not Using Online Portals
- Omegaven Available for Pediatric Parenteral Nutrition-Associated Cholestasis