Lipids and Cholesterol

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Metabolic Syndrome Highly Prevalent in Patients With Plaque Psoriasis

Metabolic Syndrome Highly Prevalent in Patients With Plaque Psoriasis

Metabolic syndrome and psoriatic arthritis were highly prevalent comorbidities in patients with plaque psoriasis.

Ezetimibe Plus Statins Modestly Reduce Cardiovascular Disease Event Risk

Ezetimibe Plus Statins Modestly Reduce Cardiovascular Disease Event Risk

Ezetimibe combined with statin therapy showed modest or moderate benefits in reducing major CVD event risk.

AHA: Statin Benefits Outweigh Risks

AHA: Statin Benefits Outweigh Risks

The data showed a <0.1% risk of statin-induced muscle injury, including rhabdomyolysis, and a ~0.001% risk of serious hepatotoxicity. Statin-induced newly diagnosed diabetes mellitus was a ~0.2% risk per year of treatment, depending on baseline risk in the patients studied.

Elevated Triglyceride Levels Affect Glycemic Control in Type 2 Diabetes

Elevated Triglyceride Levels Affect Glycemic Control in Type 2 Diabetes

Reducing triglyceride levels in patients with type 2 diabetes may help them attain more optimal glycemic control.

Statin Use May Improve Bone Microstructure in Women With Osteoporosis

Statin Use May Improve Bone Microstructure in Women With Osteoporosis

Statin use is associated with better cortical bone characteristics in older women with osteoporosis, but results are dependent upon the potency of the statins.

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

The addition of ezetimibe to simvastatin reduced ischemic risk compared with placebo, with consistent relative risk reductions in patients with and without polyvascular disease.

Digital Obesity Treatment in Primary Care May Help Disadvantaged Patients

Digital Obesity Treatment in Primary Care May Help Disadvantaged Patients

Socioeconomically challenged patients with obesity and elevated cardiovascular risk may benefit from digital obesity treatment combined with health system resources.

Omega-3 Fatty Acids Reduce Major CV Events in Mild Hypertriglyceridemia

Omega-3 Fatty Acids Reduce Major CV Events in Mild Hypertriglyceridemia

In high-risk patients with mild hypertriglyceridemia, omega-3 fatty acids improved triglyceride levels and reduced major adverse cardiovascular events, according to a new meta-analysis.

Simvastatin Improves Inflammation, Platelet Activation Markers in Primary Hypercholesterolemia

Simvastatin Improves Inflammation, Platelet Activation Markers in Primary Hypercholesterolemia

In patients with primary hypercholesterolemia, short-term treatment with simvastatin improved the lipid profile and exerted a beneficial effect on a wide range of proatherogenic and prothrombotic parameters.

Alirocumab Well Tolerated and Effective in Patients With Statin Intolerance

Alirocumab Well Tolerated and Effective in Patients With Statin Intolerance

Researcher observed a much lower rate of discontinuations due to skeletal muscle events with alirocumab in the open-label extension trial compared with the double-blind parent study (3.2% vs 15.9%).

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