Increased PT Only: A Prolonged PT with a Normal PTT
Initiation of Coumadin therapy or a very low dose of Coumadin
Inadequate intake of foods rich in vitamin K, such as cauliflower, broccoli, chick peas, other leafy vegetables
A stimulus for disseminated intravascular coagulation (DIC)
Evidence of liver disease from clinical or laboratory parameters
Family history of bleeding that could be associated with factor VII deficiency
Suggested Additional Lab Testing
Get liver function tests to assess whether the patient has liver disease and decreased synthesis of coagulation factors from the liver
Get a D-dimer or FDP as an assessment of DIC
If the test is positive, follow up with platelet count and measurement of fibrinogen.
In patients with DIC, these can be decreased or show decreasing values in two consecutive specimens at least several hours apart.
If DIC, Coumadin therapy, and vitamin K deficiency have been ruled out, measure the factor VII level and assess the possibility of an isolated factor VII deficiency.
Copyright © 2017, 2013 Decision Support in Medicine, LLC. All rights reserved.
No sponsor or advertiser has participated in, approved or paid for the content provided by Decision Support in Medicine LLC. The Licensed Content is the property of and copyrighted by DSM.
Endocrinology Advisor Articles
- FDA Approves Marketing of 2 Devices to Detect Parathyroid Tissue in Real Time
- Long-Term Efficacy and Safety of Dapagliflozin for Type 1 Diabetes
- Diabetes Education Week 2018: Patient Resources for Your Practice
- Measuring Time in Range During CGM May Be Useful Outcome Metric for Clinical Trials
- Cardiometabolic Disease Patterns Related to Race, Ethnicity in Midlife Women
- HHS: Updated Physical Activity Guidelines for Americans Released
- HbA1c Variability in General Population Increases Risk for Cardiovascular Events, All-Cause Mortality
- Multiple Daily Injections vs Insulin Pump Therapy in Pregnant Women With T1D
- Pathogenesis of Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass in T2D
- Progress Toward Goals in Global Health Is Slowing