Researchers investigated effects of eplerenone on insulin sensitivity, inflammatory indices, and other metabolic parameters in HIV.
Findings highlight the importance of screening for metabolic syndrome (MS) and the potential for MS to influence alanine aminotransferase and its interpretation in the context of HBV treatment decisions.
In patients with insulin-treated diabetes and sepsis, increased highest glucose levels and glycemic variability have a significant illness severity-adjusted association with decreasing in-hospital mortality.
The Copenhagen Co-morbidity in HIV Infection (COCOMO) study assessed the association between risk factors for cardiovascular disease and HIV infection.
More research is needed to better capture the interplay between prediabetes/diabetes and antiretroviral therapy in people with HIV.
Among a large US cohort of patients treated for HCV, patients who achieved sustained virologic response demonstrated a substantially lower risk for development of type 2 diabetes than patients with treatment failure.
For patients with chronic hepatitis B virus, body mass index is significantly associated with increased risk of hepatocellular carcinoma, with the risk more pronounced for women than men.
Early treatment and elimination of hepatitis C virus with direct-antiviral agents in patients with related cirrhosis may improve glucose tolerance and reduce the risk for diabetes development.
Even modest gains in abdominal fat in HIV-positive men undergoing long-term viral treatment are associated with the development of diabetes.
Patients with type 2 diabetes treated with sulfonylureas may be at a higher risk of contracting tuberculosis, compared with patients treated with metformin.
Patients with diabetes had higher rates for all 19 infection categories with the highest incidence rate ratios seen for bone and joint infections, sepsis, and cellulitis.
Researchers examined the benefits and risks associated with delaying ART initiation to slow bone mineral density loss.
Bone mineral density of the femoral neck, a significant predictor of fracture risk, declined nearly twice as quickly in HIV-infected women compared with HIV-infected men.
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