Hypogonadism

New Testosterone Replacement Therapy Approved for At-Home Self-Administration

New Testosterone Replacement Therapy Approved for At-Home Self-Administration

By

Xyosted carries a Boxed Warning regarding blood pressure increases that may potentially increase the risk for major adverse cardiovascular events.

Case Report Reveals Another Possible Side Effect of Kratom

Case Report Reveals Another Possible Side Effect of Kratom

By

A number of adverse events or side effects have been reported, but this is the first report of hyperprolactinemia as the result of ingestion of kratom.

Updated Clinical Practice Guidelines on Testosterone Therapy in Men With Hypogonadism

Updated Clinical Practice Guidelines on Testosterone Therapy in Men With Hypogonadism

By

Testosterone therapy is recommended in men with hypogonadism to correct symptoms of testosterone deficiency. Men who are otherwise healthy do not need to be screened for hypogonadism.

Low Sperm Count Linked to Poor Metabolic, Cardiovascular, Bone Health

Low Sperm Count Linked to Poor Metabolic, Cardiovascular, Bone Health

By

Researchers tested whether semen quality and reproductive function could be a marker of general health in men.

Testosterone Therapy Prescribing Practices in VA Setting

Testosterone Therapy Prescribing Practices in VA Setting

By

Patients attending VA clinics may experience variability in testosterone prescribing practices for hypogonadism.

Long-Term Testosterone Treatment Reduced HbA1c in Men With Hypogonadism and Type 2 Diabetes

Long-Term Testosterone Treatment Reduced HbA1c in Men With Hypogonadism and Type 2 Diabetes

By

At 12 years of testosterone treatment, HbA1c decreased to 5.5±0.3%.

Adherence to Topical Testosterone Therapy in Primary and Secondary Hypogonadism

Adherence to Topical Testosterone Therapy in Primary and Secondary Hypogonadism

By

Low adherence to topical testosterone therapy has been linked to lowered total testosterone values and poor outcomes.

Testosterone Replacement Therapy May Protect Against Stroke, Heart Attack in Hypogonadism

Testosterone Replacement Therapy May Protect Against Stroke, Heart Attack in Hypogonadism

By

There has been growing concern that testosterone replacement therapy is associated with adverse cardiovascular outcomes.

Harmonized Testosterone Reference Ranges Established for Men

Harmonized Testosterone Reference Ranges Established for Men

By

Researchers have pinpointed harmonized references ranges for total testosterone levels in men.

Implantable Testosterone Pellets Associated With Small Hematocrit Increase

Implantable Testosterone Pellets Associated With Small Hematocrit Increase

Men treated with implantable testosterone pellets have a statistically significant increase in mean hematocrit, but it is unlikely to be clinically relevant.

Once-Daily Testosterone Solution Beneficial in Androgen Deficiency

Once-Daily Testosterone Solution Beneficial in Androgen Deficiency

Once-daily testosterone solution 2% (T-sol) is safe and improves sex drive and energy in men with androgen deficiency.

Testosterone Solution Found Safe, Effective for Hypogonadal Men

Testosterone Solution Found Safe, Effective for Hypogonadal Men

Once-daily 2% testosterone solution (T-sol) is safe and effective for sex drive and energy in hypogonadal men.

Testosterone Gel Moderately Improved Sexual Function in Older Men

Testosterone Gel Moderately Improved Sexual Function in Older Men

Men using testosterone gel experienced improvements in sex drive, sexual activity, and erectile function.

Testosterone Undecanoate May Reduce Anemia in Men With Hypogonadism

Testosterone Undecanoate May Reduce Anemia in Men With Hypogonadism

Results showed a decreased prevalence of anemia and components of metabolic syndrome after 54 weeks of treatment.

Low Testosterone, Sarcopenia Predicted Mortality in Advanced Liver Disease

Low Testosterone, Sarcopenia Predicted Mortality in Advanced Liver Disease

Both low testosterone and sarcopenia tied to increased mortality, with low testosterone being a better predictor.

Topical Testosterone Effectively Restores Normal Testosterone Levels in Men

Topical Testosterone Effectively Restores Normal Testosterone Levels in Men

Daily topical testosterone restored normal testosterone levels in hypogonadal men

T Trial: Testosterone Therapy May Have Modest Benefits for Older Men

T Trial: Testosterone Therapy May Have Modest Benefits for Older Men

By

Sexual function and mood and depressive symptoms were improved in older men who received testosterone therapy.

Secondary Hypogonadism: Causes and Potential Treatment

Secondary Hypogonadism: Causes and Potential Treatment

By

Selective estrogen receptor modulators may offer a viable treatment option for men with secondary hypogonadism.

Opioid Exposure May Increase Odds for Low Testosterone

Opioid Exposure May Increase Odds for Low Testosterone

Researchers found an increased odds of low testosterone with exposure as well as an increased odds with increasing age and comorbidities.

Potential Discontinuation of Testosterone Nasal Gel Supply in 2016

Potential Discontinuation of Testosterone Nasal Gel Supply in 2016

By

Acerus announced that its agreement with an affiliate of Endo International plc regarding the commercialization of Natesto (testosterone) nasal gel in the U.S. and Mexico will be terminated as of June 30, 2016.

High Protein Intake May Lower Testosterone in Premenopausal Women

High Protein Intake May Lower Testosterone in Premenopausal Women

By

Eating more protein may lower testosterone levels in women.

AACE Questions Link Between Testosterone Therapy, Cardiovascular Risks

AACE Questions Link Between Testosterone Therapy, Cardiovascular Risks

By

American Association of Clinical Endocrinologists issues position statement on CV risks of testosterone therapy.

Experts: More Study of CV Safety of Testosterone Therapy Necessary

Experts: More Study of CV Safety of Testosterone Therapy Necessary

Experts suggest that more studies are necessary to evaluate testosterone therapy in men with age-related hypogonadism.

Testosterone Not Associated With Atherosclerosis in Older Men

Testosterone Not Associated With Atherosclerosis in Older Men

Researchers observed no impact on rate of change of intima-media thickness, coronary artery calcium score.

Low Testosterone May Be Risk Factor for Prostate Cancer Detection

Low Testosterone May Be Risk Factor for Prostate Cancer Detection

By

Prostate cancer is more likely to be found in men with low testosterone vs. those with normal levels.

Review: Hypogonadism Guidelines Require Updating

Review: Hypogonadism Guidelines Require Updating

By

Quality studies are still needed to answer crucial questions about TRT and prostate cancer, cardiovascular risk.

Testosterone Therapy Not Linked to Increased VTE Risk

Testosterone Therapy Not Linked to Increased VTE Risk

These findings are based on data from more than 30,000 American men aged 40 years and older.

Testosterone Therapy Failed to Improve Ejaculatory Dysfunction

Testosterone Therapy Failed to Improve Ejaculatory Dysfunction

By

Undergoing testosterone replacement therapy didn't improve ejaculatory dysfunction in men with testosterone deficiency.

More Men With Borderline Testosterone Have Depression

More Men With Borderline Testosterone Have Depression

More than half have depression or depressive symptoms, and 25% are taking antidepressants.

Testosterone Plus Fenofibrate Yields Strongest Cardiometabolic Benefit

Testosterone Plus Fenofibrate Yields Strongest Cardiometabolic Benefit

Findings in older men with high cholesterol and low testosterone.

Sign Up for Free e-Newsletters



CME Focus