Xyosted carries a Boxed Warning regarding blood pressure increases that may potentially increase the risk for major adverse cardiovascular events.
A number of adverse events or side effects have been reported, but this is the first report of hyperprolactinemia as the result of ingestion of kratom.
Testosterone therapy is recommended in men with hypogonadism to correct symptoms of testosterone deficiency. Men who are otherwise healthy do not need to be screened for hypogonadism.
Researchers tested whether semen quality and reproductive function could be a marker of general health in men.
Patients attending VA clinics may experience variability in testosterone prescribing practices for hypogonadism.
At 12 years of testosterone treatment, HbA1c decreased to 5.5±0.3%.
Low adherence to topical testosterone therapy has been linked to lowered total testosterone values and poor outcomes.
There has been growing concern that testosterone replacement therapy is associated with adverse cardiovascular outcomes.
Researchers have pinpointed harmonized references ranges for total testosterone levels in men.
Men treated with implantable testosterone pellets have a statistically significant increase in mean hematocrit, but it is unlikely to be clinically relevant.
Once-daily testosterone solution 2% (T-sol) is safe and improves sex drive and energy in men with androgen deficiency.
Once-daily 2% testosterone solution (T-sol) is safe and effective for sex drive and energy in hypogonadal men.
Men using testosterone gel experienced improvements in sex drive, sexual activity, and erectile function.
Results showed a decreased prevalence of anemia and components of metabolic syndrome after 54 weeks of treatment.
Both low testosterone and sarcopenia tied to increased mortality, with low testosterone being a better predictor.
Daily topical testosterone restored normal testosterone levels in hypogonadal men
Sexual function and mood and depressive symptoms were improved in older men who received testosterone therapy.
Selective estrogen receptor modulators may offer a viable treatment option for men with secondary hypogonadism.
Researchers found an increased odds of low testosterone with exposure as well as an increased odds with increasing age and comorbidities.
Acerus announced that its agreement with an affiliate of Endo International plc regarding the commercialization of Natesto (testosterone) nasal gel in the U.S. and Mexico will be terminated as of June 30, 2016.
Eating more protein may lower testosterone levels in women.
American Association of Clinical Endocrinologists issues position statement on CV risks of testosterone therapy.
Experts suggest that more studies are necessary to evaluate testosterone therapy in men with age-related hypogonadism.
Researchers observed no impact on rate of change of intima-media thickness, coronary artery calcium score.
Prostate cancer is more likely to be found in men with low testosterone vs. those with normal levels.
Quality studies are still needed to answer crucial questions about TRT and prostate cancer, cardiovascular risk.
These findings are based on data from more than 30,000 American men aged 40 years and older.
Undergoing testosterone replacement therapy didn't improve ejaculatory dysfunction in men with testosterone deficiency.
More than half have depression or depressive symptoms, and 25% are taking antidepressants.
Findings in older men with high cholesterol and low testosterone.
Endocrinology Advisor Articles
- Diet Quality and Glycemic Control in Women With Gestational Diabetes
- Most Foods Containing Fructose Do Not Have Harmful Effect on Glycemic Control
- Hypothyroidism Treatment No Longer Available
- Endocrine-Disrupting Chemicals in Personal Care Products Linked to Early Puberty
- Normalized HbA1c Levels Facilitate Improved Neuropathy Outcomes in T2D
- Hypertensive Disorders in Pregnancy, Postpartum BMI Linked to T2D Risk
- Sleep Quality, Duration Affect Risk for Falls and Fractures in Older Women
- Physician Burnout Linked to Stress in Using Health Information Technology
- Type 2 Diabetes Linked to Colorectal Cancer Risk in Men
- Urinary Incontinence Drug May Reduce Frequency of Hot Flashes