Hypoglycemia

Lorcaserin Facilitates Weight Loss in Patients Who Are Overweight, Obese

Lorcaserin Facilitates Weight Loss in Patients Who Are Overweight, Obese

Lorcaserin facilitates sustained weight loss without increasing the rate of major cardiovascular events among overweight or obese patients.

Mini-Dose Glucagon Helps Prevent Exercise-Induced Hypoglycemia in T1D

Mini-Dose Glucagon Helps Prevent Exercise-Induced Hypoglycemia in T1D

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Mini-dose glucagon was as effective as glucose tablets for preventing hypoglycemia and may result in less post intervention hyperglycemia.

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

Fewer Major Adverse Cardiovascular Events With New Antihyperglycemic Drugs With Lower Hypoglycemic Risk

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Investigators proposed that reduction in MACE may be proportional to the magnitude of HbA1c reduction seen with newer antihyperglycemic agents.

Asymptomatic Hypoglycemia Risk With Frequent Hypoglycemia in T1D

Asymptomatic Hypoglycemia Risk With Frequent Hypoglycemia in T1D

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Investigators recorded hypoglycemic symptoms and monitored blood sugar levels by continuous glucose monitoring for 6 days.

Individuals With Type 1 Diabetes See Improvement With Continuous Glucose Monitoring

Individuals With Type 1 Diabetes See Improvement With Continuous Glucose Monitoring

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Investigators seek to determine he effects of continuous glucose monitoring on daytime and nocturnal hypoglycemia in patients with type 1 diabetes.

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

Dual-Hormone System May Lower Time in Hypoglycemia in T1D

For physically active adults with type 1 diabetes, the addition of glucagon delivery to a closed-loop system using wearable sensors with automated exercise detection is associated with reduced hypoglycemia.

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

Effects of Maternal Gestational Diabetes on Neonatal Hypoglycemia: Diet vs Insulin Treatment

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Routine screening for neonatal hypoglycemia after pregnancies complicated by gestational diabetes (GD) reveals high incidence of both mild and severe hypoglycemia for both diet-controlled and insulin-treated GD and across the full range of birth weight centiles.

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

Brief Educational Intervention Improves Awareness in Severe Hypoglycemia in T1D

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Brief structured education in addition to informed support in active insulin dose self-adjustment underpinned by targeted self-monitoring of blood glucose lead to sustained falls in severe hypoglycemia rates in individuals at high risk.

Childhood Insulin Resistance Associated With Later Psychosis

Childhood Insulin Resistance Associated With Later Psychosis

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The authors advised clinicians to carefully consider which antipsychotics they prescribe their patients with metabolic dysfunction, as some are known to be diabetogenic.

Clinicians May Be Overtreating Older Patients With Diabetes

Clinicians May Be Overtreating Older Patients With Diabetes

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Future research should further investigate the process and influences on clinician decision-making regarding individualizing glucose targets for high-risk geriatric patients, including the influence of training and practice environment.

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

Consensus Report Defines Treatment Success in β-Cell Replacement Therapy

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IPITA and EPITA held a workshop to develop consensus for a joint statement on the definition of function and failure of current and future forms of β-cell replacement therapy.

New 'Smart' CGM System Provides Predictive Alerts to Patients With Diabetes

New 'Smart' CGM System Provides Predictive Alerts to Patients With Diabetes

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Users also have access to the Company's Sugar.IQ app, which uses IBM's Watson Health platform, to identify glucose patterns based on factors that may affect them (ie, food intake, insulin dosages, daily routines).

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

Tresiba Label Updated With Data on Severe Hypoglycemia, CV Outcomes

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The Tresiba label was updated to reflect safety outcomes from the DEVOTE trial.

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

Preventing Nocturnal Hypoglycemia: Single- vs Dual-Hormone Artificial Pancreas System

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Study suggests that single-hormone artificial pancreas systems may be sufficient for overnight control even in a high-risk group of hypoglycemia-unaware participants with documented nocturnal hypoglycemia.

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

Effect of Glycemic Control During Labor on Neonatal Hypoglycemia Examined

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High-quality studies are needed to determine whether tight intrapartum glycemic control is superior to more relaxed glycemic targets intrapartum for women with diabetes in pregnancy.

Safety of Novel Soluble Glucagon Analog for Severe Hypoglycemia in T1D Evaluated

Safety of Novel Soluble Glucagon Analog for Severe Hypoglycemia in T1D Evaluated

Dasiglucagon is well-tolerated and is associated with an early pharmacodynamic response similar to that of GlucaGen for severe hypoglycemia.

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

Severe Hypoglycemia Associated With Increased Mortality Risk in T2D

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A study confirms whether severe hypoglycemia increases risk for all-cause mortality in patients with type 2 diabetes.

In-Hospital Tramadol Use Increases Hypoglycemia Risk in T1D, T2D

In-Hospital Tramadol Use Increases Hypoglycemia Risk in T1D, T2D

Results indicate that blood glucose monitoring should be conducted in hospitalized patients with diabetes.

Glucagon Response to Hypoglycemia Altered in Diabetes Secondary to Chronic Pancreatitis

Glucagon Response to Hypoglycemia Altered in Diabetes Secondary to Chronic Pancreatitis

Patients with type 2 diabetes and those with diabetes secondary to chronic pancreatitis have similarly impaired α-cell responses to oral glucose ingestion and hypoglycemia.

Management of Hypoglycemia: Insulin Degludec vs Insulin Glargine

Management of Hypoglycemia: Insulin Degludec vs Insulin Glargine

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Expert Q&A compares the effects of insulin degludec and insulin glargine U100 in patients with type 1 and type 2 diabetes.

Hypoglycemia Effectivey Managed With New Nasal Glucagon Device

Hypoglycemia Effectivey Managed With New Nasal Glucagon Device

Hypoglycemic episodes, moderate or severe, can effectively and efficiently be managed by nasal glucagon in adult patients with type 1 diabetes.

Reduced Awareness of Hypoglycemia in T1D With High-Intensity Interval Training

Reduced Awareness of Hypoglycemia in T1D With High-Intensity Interval Training

A single session of HIIT can "rapidly reduce" awareness of hypoglycemia in patients with type 1 diabetes.

Case Report: Insulin Autoimmune Syndrome Following Rituximab Therapy

Case Report: Insulin Autoimmune Syndrome Following Rituximab Therapy

A 37-year-old woman presented to the emergency department with recurrent dizziness following her recent pregnancy.

Hypoglycemia Treatment Recalled Due to Presence of Particulate Matter

Hypoglycemia Treatment Recalled Due to Presence of Particulate Matter

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A voluntary recall was announced for one specific lot of 25% dextrose injection, USP (infant).

Mortality In Type 2 Diabetes Increased With Severe Hypoglycemia Episode

Mortality In Type 2 Diabetes Increased With Severe Hypoglycemia Episode

Researchers identified hypoglycemia as an "under-recognized" risk factor for death and CVD in people with type 2 diabetes.

New Recommendation on Reporting Hypoglycemia in Clinical Trials

New Recommendation on Reporting Hypoglycemia in Clinical Trials

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Two diabetes associations are calling for more standard definitions of hypoglycemia to improve information on risk garnered during clinical trials.

Incidence of Hospitalization for Hypoglycemia Decreased in Type 1 Diabetes

Incidence of Hospitalization for Hypoglycemia Decreased in Type 1 Diabetes

For patients with type 1 diabetes, the incidence of hospitalization for hypoglycemia decreased over time in Denmark, with an 8.4% annual decrease.

Hypoglycemia in Hospitalized Patients Hikes Mortality Risk

Hypoglycemia in Hospitalized Patients Hikes Mortality Risk

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Hospitalized patients who experience hypoglycemia are at an increased risk for short-term and long-term mortality.

Gastric Emptying in Type 1 Diabetes Unaffected by Liraglutide

Gastric Emptying in Type 1 Diabetes Unaffected by Liraglutide

For individuals with type 1 diabetes, liraglutide therapy does not affect the rate of gastric emptying during hypoglycemia.

Educational Intervention Helps Reduce Severe Hypoglycemic Episodes

Educational Intervention Helps Reduce Severe Hypoglycemic Episodes

A brief, partly web-based educational intervention, HypoAware, is beneficial for reducing severe hypoglycemic episodes and improving hypoglycemia awareness compared with usual care.

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