Context:

Graves’ orbitopathy is a potentially sight-threatening disease for which available medical therapy is not uniformly successful. Multiple case series suggest that rituximab may be effective therapy for GO patients.

Objective:

To determine the efficacy of rituximab in Graves’ orbitopathy.

Patients:

Twenty five patients with active moderate to severe Graves’ orbitopathy were enrolled, and 21 completed the study to the primary endpoint.

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