The benefits of treating overt hypothyroidism in women who are pregnant or planning pregnancy are clear, but there is less clarity regarding the maternofetal and neonatal effects of subclinical hypothyroidism.
In healthy patients with papillary thyroid microcarcinomas, active surveillance may be a feasible and safe alternative to immediate surgery, according to study results published in The Journal of Clinical Endocrinology & Metabolism. There is controversy regarding optimal management of low-risk thyroid carcinomas, with active surveillance emerging as a potential alternative to surgery. However, there is…
Integrated, pooled efficacy data from the phase 2 and phase 3 OPTIC trials of teprotumumab (Horizon Therapeutics) found that the treatment led to significant reductions in inflammation, proptosis (eye bulging) and diplopia (double vision) in patients with active thyroid eye disease (TED).
Investigators abstracted data from the Avon Longitudinal Study of Parents and Children, a longitudinal birth cohort study of pregnant women, to assess the trajectory of emotional and behavioral problems in offspring.
A model developed through automated machine learning uses ultrasonographic images to classify indeterminate thyroid nodules as having low or high genetic risk.
In patients with overweight or obesity who undergo total thyroidectomy, choosing the thyroid hormone replacement dose based on body weight is frequently inaccurate and could be responsible for prolongation of the titration period.
The FDA has accepted for priority review the Biologics License Application (BLA) for teprotumumab (Horizon Therapeutics) for the treatment of active thyroid eye disease.
Patients with Graves disease in association with other autoimmune diseases had a 4-fold higher rate of transition from initial hypothyroidism to hyperthyroidism compared with patients who had isolated Graves disease.
