Thyroid

Latest News

Thyroid Peroxidase Antibody Positivity Linked to Reduced Live Birth Rate in Recurrent Pregnancy Loss

By

Hannah Dellabella

In women with unexplained recurrent pregnancy loss, thyroid peroxidase antibody positivity is associated with a reduced live birth rate.

The Different Pathways to Diagnosis and Treatment of Thyroid Microcarcinomas

By

Amit Akirov, MD

The diagnostic pathway leading to diagnosis of thyroid microcarcinoma (tumor size ≤1 cm) is very different than that of larger thyroid tumors.

Inaccuracies of Weight-Based Levothyroxine Dosing After Total Thyroidectomy

By

Amit Akirov, MD

In patients with overweight or obesity who undergo total thyroidectomy, choosing the thyroid hormone replacement dose based on body weight is frequently inaccurate and could be responsible for prolongation of the titration period.

Teprotumumab Granted Priority Review From FDA for Active Thyroid Eye Disease

By

Diana Ernst, RPh

The FDA has accepted for priority review the Biologics License Application (BLA) for teprotumumab (Horizon Therapeutics) for the treatment of active thyroid eye disease.

Clinical Presentation of Graves Disease in Isolation vs With Other Autoimmune Disorders

By

Hannah Dellabella

Patients with Graves disease in association with other autoimmune diseases had a 4-fold higher rate of transition from initial hypothyroidism to hyperthyroidism compared with patients who had isolated Graves disease.

Annual Postoperative Ultrasound May Not Be Necessary in Low-Risk Thyroid Cancer

By

Hannah Dellabella

Serum tumor markers alone can provide reliable surveillance of patients who undergo total thyroidectomy for low- and intermediate-risk papillary thyroid carcinoma.

Entractinib, a Tumor Agnostic Therapy, Receives FDA Approval

By

Brian Park, PharmD

Rozlytrek is a kinase inhibitor that selectively targets ROS1 and NTRK fusions.

Estimates of Abnormal TSH Levels in Youth Hospitalized for Psychiatric Care

About 6 percent of psychiatrically hospitalized youth have abnormal thyroid-stimulating hormone measures.

No Difference in Levothyroxine Dose in Patients With vs Without Heart Failure

By

Amit Akirov, MD

Maintenance dose of levothyroxine does not differ in patients with hypothyroidism with vs without heart failure.

Thyroid Dysfunction Common in Children Treated With Amiodarone

By

Hannah Dellabella

Children and young adults treated with amiodarone have a significant likelihood for thyroid dysfunction soon after treatment initiation.

Case Report: Severe Proximal Myopathy Can Be Secondary to Hypothyroidism, Hashimoto Thyroiditis

By

Emily Pond

This case study illustrates that severe proximal myopathy can be secondary to hypothyroidism. It also emphasizes the importance of measuring thyroid function in patients with proximal weakness, myalgia, and a significantly raised creatine kinase.