The Handoff is a weekly roundup of endocrinology and general medicine news covering various developments in subspecialties, as well as pharmaceutical industry, association, and society news.
–Despite the current popularity of testosterone therapy — possibly spurred by direct-to-consumer TV ads for “low T” — clinical trial results remain mixed on the efficacy of the therapy.
–After a brief break, the Affordable Care Act (ACA) repeal effort is back on the table, according to US Republican legislators.
–In related news, JAMA has published an infographic to illustrate US public opinion on health care reform. According to the data, the top priority among both political parties is to lower individual health care costs.
–A recent study out of Human Molecular Genetics suggests that the rarely-studied USF3 gene may predispose certain individuals to developing differentiated thyroid cancer (DTC). Researchers from the Cleveland Clinic also found a potential therapeutic strategy to target the gene.
–The Endocrine Society has released a clinical practice guideline for the treatment of functional hypothalamic amenorrhea. According to the guideline, women with this condition should receive “multidisciplinary treatment approach” that includes medical, dietary, and mental health support.
–The US Preventive Services Task Force (USPSTF) has not found enough evidence to recommend that patients without symptoms be routinely screened for celiac disease. However, in a corresponding JAMA editorial, 2 clinicians note that due to atypical or nonspecific symptoms, celiac disease can be difficult to diagnose and widespread screening would “shorten the duration of symptoms.”
–According study published in Obesity Reviews, Canadian researchers have identified 79 genetic syndromes for which obesity is the primary symptom, suggesting that while some genetic forms of obesity are rare, they are also numerous.
–A team of genomic scientists at the Icahn School of Medicine at Mount Sinai, New York and UConn School of Medicine have successfully sequenced a genome for parathyroid carcinoma, a rare cancer with numerous metabolic complications and no current effective treatment.
— In a video for Business Insider, Robert Lustig, MD, professor of pediatric endocrinology the UC San Francisco, explains one surprising result of excess sugar consumption in children: more pediatric patients are developing nonalcoholic fatty liver disease.
—ENDO 2017, the annual meeting of The Endocrine Society, kicks off on Saturday, April 1. Check out our preview article and follow Endocrinology Advisor for the latest meeting coverage.