(HealthDay News) — Childhood obesity prevention programs are beneficial for LDL cholesterol and HDL cholesterol, according to a systematic review and meta-analysis published in Obesity Reviews.

Li Cai, from Sun Yat-sen University in China, and colleagues examined the effects of childhood obesity prevention programs on blood lipids in high-income countries. Data were obtained from 17 relevant randomized controlled trials, quasi-experimental studies and natural experiments that implemented diet and/or physical activity interventions in 2- to 18-year-olds.

The pooled intervention effect was −0.97 mg/dL−1 for total cholesterol (P=.408); −6.06 mg/dL−1 for LDL (P=.018); 1.87 mg/dL−1 for HDL (P=.013); and −1.95 mg/dL−1 for triglycerides (P=.202), the researchers found.

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In 70% of interventions, there were similar significant or no effects on adiposity and lipid outcomes: Adiposity and lipid outcomes were improved in 15% of interventions, while there were no significant effects on either in 55%.

“Childhood obesity prevention programs had a significant desirable effect on LDL-C and HDL-C,” the researchers wrote. “Assessing lipids outcomes provides additional useful information on obesity prevention program benefits.”


  1. Cai L et al. Obes Rev. 2014;doi:10.1111/obr.12227.