Obesity rates are nearly 40% among US adults, but traditional treatment methods are found to contribute to weight stigma, creating a population that’s unhealthier than ever.
Topline data from the Phase 3 STELLAR-4 trial showed that selonsertib, an investigational treatment for patients with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH), was not associated with a significant improvement in fibrosis without worsening of NASH.
Most Americans are concerned about their weight and understand the connection between weight and cardiovascular health, but a substantial proportion of them are not doing much to lose excess weight.
Investigators examined a link between major cardiovascular risk factors, such as older age and smoking, and venous thromboembolism, consisting of deep vein thrombosis or pulmonary embolism.
Self-reported weight history by ethnically diverse middle-aged to older patients is independently provides prognostic information about future heart failure risk.
Children with normal timing of BMI peak who experienced an early adiposity rebound or without any BMI decline after infancy appear to have the highest risk of developing an adverse cardiometabolic profile in adolescence.
Intermittent fasting with restricted energy intake may provide better outcomes than daily continuous diet restriction for health and weight loss in obese women.
