HealthDay News — Overall, low-carbohydrate diet and low-fat diet scores are not associated with total mortality, according to a study published online Jan. 21 in JAMA Internal Medicine.
Zhilei Shan, M.D., Ph.D., from the Harvard T.H. Chan School of Public Health in Boston, and colleagues used data from the U.S. National Health and Nutrition Examination Survey (1999 to 2014) to identify 37,233 adults (mean age, 49.7 years; 52.6 percent female) with 24-hour dietary recall data.
The researchers found that 4,866 total deaths occurred during follow-up. There was no overall association between low-carbohydrate diet and low-fat diet scores and total mortality. However, for total mortality per 20-percentile increase in dietary scores, associations were seen between diet and mortality (unhealthy low-carbohydrate diet score: adjusted hazard ratio [aHR], 1.07; healthy low-carbohydrate diet score: aHR, 0.91; unhealthy low-fat diet score: aHR, 1.06; healthy low-fat diet score: aHR, 0.89).
“These findings suggest that the associations of low-carbohydrate and low-fat diets with mortality may depend on the quality and food sources of macronutrients,” the authors write.