(HealthDay News) — Breakfast consumption influences glucose regulation throughout the day in patients with diabetes, according to a small study published in Diabetes Care.
Daniela Jakubowicz, MD, from Tel Aviv University in Israel, and colleagues conducted a crossover study in which 22 patients with diabetes (mean age, 56.9 years; BMI, 28.2; and glycated hemoglobin, 7.7%) were randomly assigned to two test days: 1 day with breakfast, lunch and dinner (YesB) and another with lunch and dinner but no breakfast (NoB).
Lunch area under the curves for 0 to 180 minutes (AUC0-180) for plasma glucose, free fatty acids (FFA) and glucagon were 36.8%, 41.1% and 14.8% higher, respectively, while the AUC0-180 for insulin and intact glucagon-like peptide-1 (iGLP-1) were 17% and 19% lower, respectively, on the NoB day compared with YesB (P<.0001).
Dinner AUC0-180 for glucose, FFA and glucagon were 26.6%, 29.6% and 11.5% higher, respectively, while AUC0-180 for insulin and iGLP-1 were 7.9% and 16.5% lower, respectively, on the NoB day compared with the YesB day (P<.0001).
On the NoB day, insulin peak was delayed 30 minutes after lunch and dinner, compared with the YesB day.
“Breakfast consumption could be a successful strategy for reduction of postprandial hyperglycemia in type 2 diabetes,” the researchers wrote.