(HealthDay News) — Patients with type 1 diabetes and type 2 diabetes have increased long-term risk for death after coronary artery bypass grafting (CABG), with higher risk among those with type 1 diabetes, according to a study published in the Journal of the American College of Cardiology.

Martin J. Holzmann, MD, PhD, from the Karolinska University Hospital in Stockholm, and colleagues examined long-term survival in patients with type 1 diabetes and type 2 diabetes who underwent primary isolated CABG. 

Data were included for 39,235 patients who underwent primary isolated CABG in Sweden, of whom 1.8% had type 1 diabetes and 21% had type 2 diabetes.

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The researchers found that patients with type 1 diabetes were younger, had reduced kidney function and had more often had peripheral vascular disease compared with those with type 2 diabetes or no diabetes

Seventeen percent of patients died during a mean follow-up of 5.9 years. Among patients with type 1 diabetes and type 2 diabetes, 21% and 19% died, respectively. Compared with patients without diabetes, the adjusted hazard ratios for death in patients with type 1 diabetes and type 2 diabetes were 2.04 (95% CI, 1.72-2.42) and 1.11 (95% CI, 1.05-1.18), respectively.

“Patients with [type 1 diabetes] had more than double the long-term risk of death after CABG compared with patients without diabetes,” the researchers wrote. “The long-term risk of death in patients with [type 2 diabetes] was only slightly increased.”


  1. Holzmann MJ et al. J Am Coll Cardiol. 2015;65(16):1644-1652.