HealthDay News — For patients with type 1 diabetes, the incidence of hospitalization for hypoglycemia decreased over time in Denmark, with an 8.4% annual decrease, according to a study published in Diabetes Care.

Kazi Ishtiak-Ahmed, from the Steno Diabetes Center in Gentofte, Denmark, and colleagues used data for 17,230 patients with type 1 diabetes registered in the Danish Adult Diabetes Database from 2006 to examine nationwide incidence trends and predictors of hospitalization for hypoglycemia. Patients were followed to 2012 (mean follow-up: 3.7 years).

The researchers found that there were 2369 hospitalization for hypoglycemia events among 1735 patients with type 1 diabetes during 70,002 patient-years. With calendar time, there was a decrease in incidence rate, with an 8.4% annual decrease. Previous hospitalization for hypoglycemia, age, diabetes duration, albuminuria, and glycated hemoglobin were predictors of hospitalization for hypoglycemia.

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“This study revealed a decreasing trend in incidence of [hospitalization for hypoglycemia] in patients with type 1 diabetes,” the researchers wrote. “Previous hospitalization for hypoglycemia, longer diabetes duration, macro-albuminuria, and HbA1c were associated with increased risk of [hospitalization for hypoglycemia] in type 1 diabetes, and attention to those factors is warranted in both clinical and public health aspects.”

Disclosures: Steno Diabetes Center is a hospital owned by Novo Nordisk; several authors disclosed financial ties to Novo Nordisk and other pharmaceutical companies.

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  1. Ishtiak-Ahmed K, Carstensen B, Pedersen-Bjergaard U, Jørgensen ME. Incidence trends and predictors of hospitalization for hypoglycemia in 17,230 adult patients with type 1 diabetes: a Danish register linkage cohort study. Diabetes Care. 2016 Nov 29. doi:10.2337/dc16-0862.