HealthDay News — Young adults with type 1 diabetes have altered neural responses during working memory processing, according to a study published in Diabetes.

Christine M. Embury, from the University of Nebraska Medical Center in Omaha, and colleagues examined the correlation between diabetes and cognitive impairment in a cohort of young adults with and without type 1 diabetes who were virtually free of comorbidities that have been independently linked to cognitive deficits (such as obesity and hypertension).

Participants completed a verbal working memory task during magnetoencephalographic brain imaging.

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The researchers found that, compared with controls, patients had significantly stronger neural responses in the superior parietal cortices during memory encoding, while during maintenance, activity was significantly weaker in parietal-occipital regions. There were significant correlations for disease duration and glycemic control with neural responses in various brain regions.

“Young healthy adults with type 1 diabetes already have aberrant neural processing relative to their nondiabetic peers, employing compensatory responses to perform the task, and glucose management and duration may play a central role,” the authors write.

One author disclosed financial ties to the pharmaceutical industry.

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