Type 1 Diabetes

Latest News

Study Compares Methods to Prevent Hypoglycemia During Exercise in Type 1 Diabetes

By

Rose Reeb

Carbohydrate supplementation is superior to bolus insulin reductions for the prevention of hypoglycemia during exercise in people with type 1 diabetes.

Better Glycemic Control Linked to Preserved Cognition After Lacunar Stroke in Diabetes

Among individuals with diabetes, hemoglobin A1c is associated with cognitive scores after a lacunar stroke.

Risk for Severe COVID-19 Increased With Existing Health Conditions

In the United States, individuals with underlying health conditions have an increased risk for severe coronavirus disease 2019.

Diabetes and COVID-19: Clinical Considerations and Recommendations

By

Amit Akirov, MD

In the COVID-19 pandemic, there are specific considerations that should be made for patients with diabetes, who are at greater risk for severe infection.

Importance of Temporal Glucose Profiles During Pregnancy in Type 1 Diabetes

By

Amit Akirov, MD

Applying functional data analysis to continuous glucose monitoring data can assist in identifying differences in maternal glucose control during pregnancy, which might go unnoticed using standard metrics.

FDA Denies Approval of Empagliflozin for Type 1 Diabetes

By

Brian Park, PharmD

The FDA is unable to approve the sNDA for empagliflozin 2.5mg as an adjunct to insulin for type 1 diabetes in its current form.

Rapid Corneal Nerve Fiber Loss Is a Potential Biomarker for Diabetic Polyneuropathy

By

Amit Akirov, MD

Abnormally rapid corneal nerve fiber loss may indicate increased risk for the development and progression of diabetic distal symmetric polyneuropathy.

FDA: Biologic Drugs, Including Insulin, Transitioned to New Regulatory Pathway

Insulin and other biologic drugs, have now transitioned to being regulated as biological products, providing a new pathway for approval of biosimilars and interchangeable versions of these products and introducing competition into the market.

Trends in Hyperglycemic Emergencies From 2006 to 2015 Show Increases in DKA, HHS

From 2009 to 2015, there were increases in diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) events among adults.

Antibiotics in First Year of Life May Increase Risk for T1D by Age 10

Antibiotic prescriptions in the first year of life are associated with an increased risk for type 1 diabetes in childhood.

CGM Use Improves Sleep of Children With T1D but May Disrupt Parents’ Sleep

By

Rose Reeb

Use of continuous glucose monitoring devices positively correlated with fewer sleep disturbances in children with type 1 diabetes but higher sleep disturbances in their parents.

Evidence of Familial Coaggregation of Asthma, Type 1 Diabetes in Children

There is evidence for co-occurrence and coaggregation of asthma and type 1 diabetes in children and their siblings.

Rotavirus Vaccination and Type 1 Diabetes: Is There a Link?

By

Cassandra Pardini, PharmD

Rotavirus vaccination does not appear to increase or decrease the risk of developing type 1 diabetes, according to the findings of a recently published retrospective cohort study.

Suboptimal Adherence to ACE Inhibitors, Statins in Adolescents With Type 1 Diabetes

By

Amit Akirov, MD

Although medication adherence to both angiotensin-converting enzyme inhibitors and statins is initially high in adolescents with type 1 diabetes, it frequently deteriorates over time.

Is There a Role for Short-Acting Exenatide in Type 1 Diabetes?

By

Amit Akirov, MD

Short-acting preprandial exenatide as an add-on to insulin treatment in patients with type 1 diabetes had no clinically relevant effects on glycemic control or other glycemic measures.

O3 Exposure in First Trimester Associated With Pediatric Diabetes

By

Rose Reeb

Exposure to ozone during the first trimester of pregnancy is associated with pediatric diabetes incidence.

Insulin Glargine Use Not Associated With Increased Breast Cancer Risk in Older Women

By

Morgan E. Meissner

Compared with other insulins, use of insulin glargine is not associated with increased risk for breast cancer in women over 65 years of age.

Unregulated Insulin, Among Other Medications, Is Readily Available on Craigslist

Prescription medications, especially analog insulin, can be found on Craigslist.

Insulin Pen With Bolus Calculator App Cleared by FDA for Fixed Dosing, Meal Estimation

By

Brian Park, PharmD

Companion Medical announced that it has received clearance from the Food and Drug Administration (FDA) for a new bolus calculator for fixed dosing and meal estimation to be used with the InPen system.

Prevention and Treatment of Diabetic Foot Ulcers May Benefit From Multimodal Approach

By

Brandon May

A number of recent adjunctive therapy trends in the management of diabetic foot ulcers show promise and may become the new standard of care.