Metformin Improves Peripheral Insulin Sensitivity in Young Patients With Type 1 Diabetes
Metformin might improve whole-body and peripheral insulin sensitivity in overweight/obese adolescents with type 1 diabetes.
Type 1 Diabetes
TYPE 1 DIABETES
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C-Peptide Responsiveness During OGTT May Explain HbA1c Variation at T1D Diagnosis
The addition of timing measures of C-peptide responsiveness may partly explain the glycated hemoglobin variation at diagnosis of type 1 diabetes.
Home-Based Video Visits Useful for Pediatric Patients With Poorly Controlled Type 1 Diabetes
Pediatric patients with poorly controlled type 1 diabetes consider home-based video visits with healthcare providers to be feasible and satisfactory.
No Increased Risk for Diabetes After HPV Vaccination
There was no increased risk for development of diabetes mellitus type 1 after vaccination for human papilloma virus.
Wearable Device for Heart Rate Variability Can Detect Early Hypoglycemia
A wearable device that measures real-time heart rate variability can detect early signs of hypoglycemia in patients with type 1 diabetes.
Closed-Loop Insulin Delivery Associated With Lower Insulin Doses in Children With T1D
Closed-loop insulin administration appears to be better targeted and may be more effective in children with type 1 diabetes compared with sensor-augmented pump therapy.
Hypoglycemia Often Unrecognized by Older Adults With T1D
Blood sugar levels of older adults with type 1 diabetes are in the hypoglycemic range for more than an hour a day, and blood sugar levels of those with impaired hypoglycemia awareness may be in hypoglycemic range even longer.
FDA Rejects Zynquista NDA for Type 1 Diabetes Treatment
The FDA issued a Complete Response Letter rejecting the New Drug Application (NDA) for Zynquista (sotagliflozin; Sanofi and Lexicon) for the treatment of adults with type 1 diabetes, in combination with insulin.
Success of Insulin Pump Therapy Predicted by Pre-Pump Glycemic Control in T1D
Hemoglobin A1c levels before the initiation of insulin pump therapy predicted the extent to which insulin pump therapy improved glycemic control in children with type 1 diabetes.
Gluten Intake Does Not Increase Risk for Islet Autoimmunity, T1D in High-Risk Children
There is no significant association between gluten intake and development of islet autoimmunity or type 1 diabetes in children at increased risk for diabetes.
Basal Insulin Reduction 90 Minutes Before Exercise Beneficial for Glucose Control, Hypoglycemia Risk in T1D
A 50% to 80% basal rate reduction performed 90 minutes before beginning exercise will improve open-loop glucose control and decrease the risk for hypoglycemia during exercise in individuals with type 1 diabetes.
Increased Ankle-Brachial Index May Identify Patients With T1D at Risk for Cardiovascular Autonomic Dysfunction
High ankle-brachial index, a marker of arterial stiffness, may be used to assess the risk for cardiovascular autonomic neuropathy in type 1 diabetes.
Differences in Diabetes Technology Reimbursement for Children With T1D
Access to technologies for type 1 diabetes treatment such as insulins, insulin pumps, glucometers, and continuous glucose monitoring devices is varied because of reimbursement policies.
Is the Glucose Management Indicator a Useful Tool to Measure HbA1c?
Most patients with type 1 diabetes will experience clinically meaningful differences in glucose level results when comparing laboratory-measured HbA1c levels with HbA1c levels derived from a glucose management indicator.
Higher Insulin Doses Do Not Increase Adverse CV Outcomes in T1D
The use higher insulin doses in patients with type 1 diabetes can alter several cardiovascular risk factors without increasing cardiovascular outcomes.
Closed-Loop Insulin Delivery Safe for Use in Very Young Children With T1D
Unrestricted home use of day and night hybrid closed-loop insulin is safe and feasible for very young children.
Higher Levels of Vitamin D Binding Protein at Delivery Linked With Lower Risk for T1D in Offspring
Higher levels of vitamin D-binding protein at the time of delivery, but not during the middle of pregnancy, were associated with a lower risk for type 1 diabetes.
Standardized Test Scores of Children With vs Without T1D
No significant difference was found between the standardized reading and math test scores of children with type 1 diabetes and those without.
New Genetic Risk Score Better Differentiates Diabetes Types, May Be Useful in Newborn Screening
An improved genetic risk score for type 1 diabetes significantly improved identification of persons with type 1 diabetes from those with type 2 diabetes and was useful in identifying adult incident diabetes in newborn screening.
Poor Glycemic Control Increases Fracture Risk in T1D
Poor glycemic control in patients with newly diagnosed type 1 diabetes, but not type 2 diabetes, was associated with an increased risk for low-trauma fracture.
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