(HealthDay News) — The effects of treatment of mild gestational diabetes on long-term child health are unclear, according to research published in Diabetes Care.
Mark B. Landon, MD, of The Ohio State University in Columbus, and colleagues conducted a follow-up study of 500 of 905 eligible children, aged 5 to 10 years, born to mothers who had participated in a randomized trial of treatment vs. no treatment for mild gestational diabetes.
The researchers found no significant difference in the frequencies of BMI ≥95th percentile and 85th percentile for treated vs. untreated offspring (20.8% vs. 22.9% and 32.6% vs. 38.6%, respectively).
No associations were found between treatment of gestational diabetes and other cardiometabolic factors such as blood pressure (BP), waist circumference, triglyceride levels and HDL cholesterol levels.
Significantly lower fasting blood glucose levels were observed in female offspring of women treated for gestational diabetes.
“Although treatment for mild [gestational diabetes] has been associated with neonatal benefits, no reduction in childhood obesity or metabolic dysfunction in the offspring of treated women was found,” the researchers wrote. “However, only female offspring of women treated for mild [gestational diabetes] had lower fasting glucose.”