(HealthDay News) — For adults with diabetes, inadequately controlled risk factors account for a considerable proportion of cardiovascular (CV) events and death, according to a study published online in Diabetes Care.

Gabriela Vazquez-Benitez, PhD, from the HealthPartners Institute for Education and Research in Minneapolis, Minnesota, and colleagues examined the incidence of major CV hospitalization events and all-cause death among 859,617 adults with diabetes and with or without cardiovascular disease (CVD; 31% had CVD). 

The authors assessed the correlation between inadequately controlled risk factors (glycated hemoglobin, high LDL cholesterol, high blood pressure [BP], current smoking) and the incidence of major CV events.

The researchers found that per 100 person-years, event rates for adults with diabetes with CVD vs. without CVD were 6.0 vs. 1.7 for myocardial infarction (MI)/acute coronary syndrome, 5.3 vs.1.5 for stroke, 8.4 vs. 1.2 for heart failure, 18.1 vs. 4.0 for all CV events, and 23.5 vs. 5.0 for all-cause mortality. 

Inadequate risk factor control was associated with 11% and 3% of CV events and deaths, respectively, among those with CVD, and with 34% and 7%, respectively, among those without CVD.

“Additional attention to traditional cardiovascular risk factors could yield further substantive reductions in cardiovascular events and mortality in adults with diabetes,” the researchers wrote.


  1. Vazquez-Benitez G et al. Diabetes Care. 2015;doi:10.2337/dc14-1877.