(HealthDay News) — The U.S. Preventive Services Task Force recommends low-dose aspirin for preeclampsia prevention in high-risk pregnant women. The findings are presented in a final recommendation statement published in the Annals of Internal Medicine.

Researchers from the U.S. Preventive Services Task Force (USPSTF) reviewed the evidence relating to the effectiveness of low-dose aspirin for preventing preeclampsia in women at increased risk. In addition, they examined the maternal and fetal harms of low-dose aspirin use during pregnancy.

Based on the evidence, the USPSTF recommends the use of low-dose aspirin (81 mg per day) as a preventive measure after 12 weeks of gestation for women at high risk for preeclampsia (Grade B recommendation). 

Continue Reading

The recommendation applies to asymptomatic pregnant women with increased preeclampsia risk, who have no contraindications or prior adverse reactions to low-dose aspirin.

“Most women are not at high risk for preeclampsia,” Michael L. LeFevre, MD, MSPH, chair of the USPSTF, said in a statement. “Before taking aspirin, pregnant women should talk to their doctor or nurse to determine their risk level and discuss if taking aspirin is right for them.”


  1. LeFevre ML et al. Ann Intern Med. 2014;doi:10.7326/M14-1884.