(HealthDay News) — For postangiography patients, metabolic syndrome is associated with increased mortality, especially in patients with stable angina, according to a study published in The American Journal of Cardiology.

Yaron Arbel, MD, from Tel Aviv University in Israel, and colleagues examined the link between metabolic syndrome and risk for long-term mortality in a cohort of 3,525 patients undergoing coronary angiography for various clinical indications.

The researchers found that 30% of the cohort had metabolic syndrome, and these patients were more likely to have advanced coronary artery disease (CAD) and acute coronary syndrome. 

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Regardless of clinical presentation, patients with metabolic syndrome had more abnormalities in their metabolic and inflammatory biomarkers. 

During a mean follow-up period of 1,614 days, there were 495 deaths. In the general cohort, metabolic syndrome correlated with an increased risk for death (HR=1.27; 95% CI, 1.01-1.56). In stable patients, metabolic syndrome had a significant impact on mortality (HR=1.55; 95% CI, 1.1-2.18), while there was no significant effect on mortality for patients with acute coronary syndrome (HR=1.11; 95% CI, 0.86-1.44).

“In conclusion, metabolic syndrome is associated with increased mortality in postangiography patients,” the researchers wrote. “Its adverse outcome is mainly seen in patients with stable angina.”


  1. Arbel Y et al. Am J Cardiol. 2015;115(3):283-287.