(HealthDay News) — Isolated systolic high blood pressure (BP) in young adulthood is a predictor of cardiovascular disease (CVD) mortality 30 years down the road, a new study suggests. The report was published in the Journal of the American College of Cardiology.

Donald Lloyd-Jones, MD, of the Northwestern University Feinberg School of Medicine in Chicago, and colleagues followed 27,081 adults, aged 18 to 49 years, enrolled in the Chicago Heart Association Detection Project in Industry Study.

Average follow-up was 31 years, during which 1,728 deaths from CVD, 1,168 deaths from coronary heart disease (CHD) and 223 from stroke occurred.


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Compared with men with optimal-normal BP, HRs for CVD and CHD mortality risk for those with isolated systolic hypertension were 1.23 (95% CI, 1.03-1.46) and 1.28 (95% CI, 1.04-1.58), respectively. Risks for women with systolic hypertension vs. optimal-normal BP were comparable, with HRs for CVD and CHD mortality risk being 1.55 (95% CI, 1.18-2.05) and 2.12 (95% CI, 1.49-3.01), respectively.

The readings to watch for: systolic pressure of 140 mm Hg or more and diastolic pressure of less than 90 mm Hg.

“Doctors should not ignore isolated systolic high blood pressure in younger adults, since it clearly has implications for their future health,” Lloyd-Jones told HealthDay.

Reference

  1. Yano Y et al. J Am Coll Cardiol. 2015;65(4):327-335.